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• W2016096699 abstract "To provide a general descriptive account of the end-organ effects of dexmedetomidine and to provide an evidence-based review of the literature regarding its use in infants and children.A computerized bibliographic search of the literature regarding dexmedetomidine.The end-organ effects of dexmedetomidine have been well studied in animal and adult human models. Adverse cardiovascular effects include occasional episodes of bradycardia with rare reports of sinus pause or cardiac arrest. Hypotension has also been reported as well as hypertension, the latter thought to be due to peripheral alpha2B agonism with peripheral vasoconstriction. Although dexmedetomidine has no direct effects on myocardial function, decreased cardiac output may result from changes in heart rate or increases in afterload. There are somewhat conflicting reports in the literature regarding its effects on ventilatory function, with some studies (both human and animal) suggesting a mild degree of respiratory depression, decreased minute ventilation, and decreased response to CO2 challenge whereas others demonstrate no effect. The central nervous system effects include sedation and analgesia with prevention of recall and memory at higher doses. Dexmedetomidine may also provide some neuroprotective activity during periods of ischemia. Applications in infants and children have included sedation during mechanical ventilation, prevention of emergence agitation following general anesthesia, provision of procedural sedation, and the prevention of withdrawal following the prolonged administration of opioids and benzodiazepines.The literature contains reports of the use of dexmedetomidine in approximately 800 pediatric patients. Given its favorable sedative and anxiolytic properties combined with its limited effects on hemodynamic and respiratory function, there is growing interest in and reports of its use in the pediatric population in various clinical scenarios." @default.
• W2016096699 created "2016-06-24" @default.
• W2016096699 creator A5048394709 @default.
• W2016096699 date "2007-03-01" @default.
• W2016096699 modified "2023-10-05" @default.
• W2016096699 title "Dexmedetomidine: Applications in pediatric critical care and pediatric anesthesiology" @default.
• W2016096699 cites W1543542120 @default.
• W2016096699 cites W1566969599 @default.
• W2016096699 cites W1576970722 @default.
• W2016096699 cites W1582968414 @default.
• W2016096699 cites W1963510932 @default.
• W2016096699 cites W1968965608 @default.
• W2016096699 cites W1969509347 @default.
• W2016096699 cites W1971101248 @default.
• W2016096699 cites W1971252491 @default.
• W2016096699 cites W1971839085 @default.
• W2016096699 cites W1972657897 @default.
• W2016096699 cites W1976031572 @default.
• W2016096699 cites W1976504313 @default.
• W2016096699 cites W1976653029 @default.
• W2016096699 cites W1981052344 @default.
• W2016096699 cites W1982139505 @default.
• W2016096699 cites W1986899046 @default.
• W2016096699 cites W1987498060 @default.
• W2016096699 cites W1987982424 @default.
• W2016096699 cites W1988207947 @default.
• W2016096699 cites W1989001129 @default.
• W2016096699 cites W1991037983 @default.
• W2016096699 cites W1991525120 @default.
• W2016096699 cites W1991941521 @default.
• W2016096699 cites W1993579218 @default.
• W2016096699 cites W1997254682 @default.
• W2016096699 cites W1997386700 @default.
• W2016096699 cites W2000505496 @default.
• W2016096699 cites W2001004783 @default.
• W2016096699 cites W2002083186 @default.
• W2016096699 cites W2002516971 @default.
• W2016096699 cites W2003775890 @default.
• W2016096699 cites W2004386171 @default.
• W2016096699 cites W2006741513 @default.
• W2016096699 cites W2012494982 @default.
• W2016096699 cites W2013604612 @default.
• W2016096699 cites W2013864444 @default.
• W2016096699 cites W2016151184 @default.
• W2016096699 cites W2017573472 @default.
• W2016096699 cites W2025378055 @default.
• W2016096699 cites W2026528961 @default.
• W2016096699 cites W2027020622 @default.
• W2016096699 cites W2027869866 @default.
• W2016096699 cites W2032022636 @default.
• W2016096699 cites W2033017054 @default.
• W2016096699 cites W2034327661 @default.
• W2016096699 cites W2037666157 @default.
• W2016096699 cites W2039215208 @default.
• W2016096699 cites W2041254147 @default.
• W2016096699 cites W2041322579 @default.
• W2016096699 cites W2041791214 @default.
• W2016096699 cites W2043508800 @default.
• W2016096699 cites W2045278770 @default.
• W2016096699 cites W2051807281 @default.
• W2016096699 cites W2052345686 @default.
• W2016096699 cites W2052783300 @default.
• W2016096699 cites W2052847819 @default.
• W2016096699 cites W2055612603 @default.
• W2016096699 cites W2055930558 @default.
• W2016096699 cites W2056888476 @default.
• W2016096699 cites W2057126625 @default.
• W2016096699 cites W2059069143 @default.
• W2016096699 cites W2060910799 @default.
• W2016096699 cites W2062483942 @default.
• W2016096699 cites W2067978100 @default.
• W2016096699 cites W2068348024 @default.
• W2016096699 cites W2070620172 @default.
• W2016096699 cites W2072675982 @default.
• W2016096699 cites W2073279176 @default.
• W2016096699 cites W2075296319 @default.
• W2016096699 cites W2075929817 @default.
• W2016096699 cites W2078833576 @default.
• W2016096699 cites W2081839248 @default.
• W2016096699 cites W2081871122 @default.
• W2016096699 cites W2088781889 @default.
• W2016096699 cites W2090061605 @default.
• W2016096699 cites W2091241231 @default.
• W2016096699 cites W2096459483 @default.
• W2016096699 cites W2099444420 @default.
• W2016096699 cites W2102945855 @default.
• W2016096699 cites W2109201402 @default.
• W2016096699 cites W2110222116 @default.
• W2016096699 cites W2113057544 @default.
• W2016096699 cites W2114804420 @default.
• W2016096699 cites W2115497603 @default.
• W2016096699 cites W2117219797 @default.
• W2016096699 cites W2118182236 @default.
• W2016096699 cites W2124190195 @default.
• W2016096699 cites W2125134115 @default.
• W2016096699 cites W2125839482 @default.
• W2016096699 cites W2129608232 @default.
• W2016096699 cites W2132842237 @default.

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