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- W2016098591 abstract "NITROFURANTOIN has been found to be useful in the treatment of genitourinary-tract infections caused by a variety of bacterial organisms, including those resistant to many other antimicrobial agents. Continuous prophylactic treatment with nitrofurantoin has even been recommended for patients with chronic infections of the urinary tract.<sup>1</sup>Occasional reports have been published about allergies and other toxic reactions to nitrofurantoin: transient alopecia,<sup>1</sup>bilirubinuria,<sup>2</sup>jaundice, drowsiness, dizziness,<sup>2, 3</sup>and slight to moderate arrest of spermatogenesis. More frequently reported untoward reactions include dermatological abnormalities,<sup>1-4</sup>hematological manifestations,<sup>3,5,6</sup>peripheral neuritis,<sup>3,7</sup>and nausea and vomiting.<sup>2,4</sup>Sensitivity to nitrofurantoin was described by Israel and Diamond<sup>8</sup>in a patient with recurrent pulmonary infiltration and pleural effusion. The most dramatic, as well as the most serious, toxic manifestation of treatment with nitrofurantoin is an anaphylactoid reaction. Fisk<sup>9</sup>reported a patient who suffered from headache, epigastric pain radiating to the" @default.
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- W2016098591 date "1963-05-11" @default.
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- W2016098591 title "Anaphylactic Reaction Caused by Treatment with Nitrofurantoin" @default.
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- W2016098591 doi "https://doi.org/10.1001/jama.1963.73700190016021a" @default.
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