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- W2016098664 abstract "The relative biological effectiveness (RBE) and oxygen enhancement ratio (OER) were determined for fast neutron beams produced by both 16-MeV and 50-MeV $sup 2$H on Be at the Texas A and M Variable Energy Cyclotron (TAMVEC). These beams have average neutron energies of 7 and 21 MeV, respectively. The biological system used in these experiments was Chinese hamster ovary cells in tissue culture. The results indicated that although the RBE of the 21-MeV beam was about 15 percent lower than that for the 7-MeV beam at 0.1 percent survival there was no change in RBE for either beam with depth in a tissue-equivalent phantom. The OER of the 7-MeV beam was found to be 1.5 +- 0.3 and the 21-MeV beam had an OER of 1.2 +- 0.2, which resulted in gain factors of 1.7 and 2.1, respectively, when compared to $sup 60$Co gamma rays (OER = 2.5). No variation in OER with depth was detected. It was concluded that the 21-MeV TAMVEC beam should be as applicable to radiotherapy from the radiobiological point of view as a 7-MeV beam. (auth)" @default.
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- W2016098664 title "The Response of Chinese Hamster Ovary Cells to Fast Neutron Radiotherapy Beams: I. Relative Biological Effectiveness and Oxygen Enhancement Ratio" @default.
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- W2016098664 doi "https://doi.org/10.2307/3574288" @default.
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