FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016099267> ?p ?o ?g. }

• W2016099267 endingPage "2986" @default.
• W2016099267 startingPage "2976" @default.
• W2016099267 abstract "Antimicrobial activity of secondary and tertiary poly(diallylammonium) salts (PDAAs) had not been reported before. Due to difficulties with preparation of polymers from the monomers of the diallylamine (DAA) series in the nonquaternary form, up to recently it was not possible to obtain PDAAs with a sufficiently high molecular mass. Here, we describe the investigations of antimicrobial activity of novel water-soluble cationic polyelectrolytes of the PDAA series, namely secondary poly(diallylammonium trifluoroacetate) (PDAATFA) and tertiary poly(diallylmethylammonium trifluoroacetate) (PDAMATFA), in synthesis of which we have recently succeeded, against gram-positive and gram-negative bacteria, and fungi. We have studied the effect of molecular weight (polymeric chain length) and ionic strength of solution on the biocidal efficiency of those polymers; in addition, the concentration dependences of PDAATFA reduced viscosity in salt-free and KCl aqueous solutions have been investigated. The antimicrobial properties of polybase polydiallylamine (BPDAA), which was obtained in an aqueous solution of PDAATFA in presence of alkali, have been also studied as well as biocidal activity of commercial open-chain polybase branched PEI. Those PDAATFA, BPDAA and PEI polymers served as the systems to study the structure-activity relationships. Transmission electronic microscopy study was carried out to characterize the mode of antimicrobial action of PDAATFA using E. coli . It was shown that the synthesized PDAATFA and PDAMATFA exhibit, unlike the quaternary polymers of this series, a rather high biocidal efficiency that is comparable with the activity of known effective cationic polymer biocides or exceeds it. Novel polyelectrolytes exhibit quite strong biocidal properties at different conditions including aqueous solutions of moderate ionic strength (serum, 0.01 M/0.1 M) and aqueous-alkaline solutions (pH 10.5) until the macrochain retains some positive charge, but complete neutralization of the polyelectrolyte in a 1 M salt solution results in the loss of its biocidal activity. The obtained results evidence that the structure of links, which combine the hydrophobic pyrrolidinium rings with the hydrophilic secondary/tertiary ammonium groups, is responsible for the high biocidal activity of the PDAAs. Polymeric nature of the synthesized compounds is one of the most significant factors of their bactericidal efficiency, unlike their high fungicidal activity, which is evidently related to the secondary/tertiary pyrrolidinium cycle." @default.
• W2016099267 created "2016-06-24" @default.
• W2016099267 creator A5014915479 @default.
• W2016099267 creator A5026226353 @default.
• W2016099267 creator A5067908771 @default.
• W2016099267 creator A5090508228 @default.
• W2016099267 date "2009-10-01" @default.
• W2016099267 modified "2023-09-29" @default.
• W2016099267 title "Secondary and Tertiary Polydiallylammonium Salts: Novel Polymers with High Antimicrobial Activity" @default.
• W2016099267 cites W1789957917 @default.
• W2016099267 cites W1903533054 @default.
• W2016099267 cites W1985045541 @default.
• W2016099267 cites W1986506708 @default.
• W2016099267 cites W1988150820 @default.
• W2016099267 cites W1991256942 @default.
• W2016099267 cites W1996275832 @default.
• W2016099267 cites W1998585307 @default.
• W2016099267 cites W1999672814 @default.
• W2016099267 cites W2004759340 @default.
• W2016099267 cites W2009358391 @default.
• W2016099267 cites W2012866835 @default.
• W2016099267 cites W2015532922 @default.
• W2016099267 cites W2017126611 @default.
• W2016099267 cites W2019436305 @default.
• W2016099267 cites W2021320429 @default.
• W2016099267 cites W2022391656 @default.
• W2016099267 cites W2024156929 @default.
• W2016099267 cites W2031953722 @default.
• W2016099267 cites W2036796557 @default.
• W2016099267 cites W2038968326 @default.
• W2016099267 cites W2041474155 @default.
• W2016099267 cites W2054373686 @default.
• W2016099267 cites W2062672574 @default.
• W2016099267 cites W2063739164 @default.
• W2016099267 cites W2065738977 @default.
• W2016099267 cites W2066975133 @default.
• W2016099267 cites W2073699216 @default.
• W2016099267 cites W2074693164 @default.
• W2016099267 cites W2081172182 @default.
• W2016099267 cites W2081716332 @default.
• W2016099267 cites W2088165413 @default.
• W2016099267 cites W2114684886 @default.
• W2016099267 cites W2124879496 @default.
• W2016099267 cites W2127911529 @default.
• W2016099267 cites W2130829765 @default.
• W2016099267 cites W2131380952 @default.
• W2016099267 cites W2135465392 @default.
• W2016099267 cites W2142665028 @default.
• W2016099267 cites W2144149632 @default.
• W2016099267 cites W2149102577 @default.
• W2016099267 cites W2153842659 @default.
• W2016099267 cites W2156845416 @default.
• W2016099267 cites W2162963173 @default.
• W2016099267 cites W2164679906 @default.
• W2016099267 cites W2317506667 @default.
• W2016099267 cites W2328461087 @default.
• W2016099267 cites W2331172244 @default.
• W2016099267 cites W2332750764 @default.
• W2016099267 cites W4295749830 @default.
• W2016099267 cites W4301010607 @default.
• W2016099267 doi "https://doi.org/10.1021/bm900435v" @default.
• W2016099267 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19795886" @default.
• W2016099267 hasPublicationYear "2009" @default.
• W2016099267 type Work @default.
• W2016099267 sameAs 2016099267 @default.
• W2016099267 citedByCount "74" @default.
• W2016099267 countsByYear W20160992672012 @default.
• W2016099267 countsByYear W20160992672013 @default.
• W2016099267 countsByYear W20160992672014 @default.
• W2016099267 countsByYear W20160992672015 @default.
• W2016099267 countsByYear W20160992672016 @default.
• W2016099267 countsByYear W20160992672017 @default.
• W2016099267 countsByYear W20160992672018 @default.
• W2016099267 countsByYear W20160992672019 @default.
• W2016099267 countsByYear W20160992672020 @default.
• W2016099267 countsByYear W20160992672021 @default.
• W2016099267 countsByYear W20160992672022 @default.
• W2016099267 countsByYear W20160992672023 @default.
• W2016099267 crossrefType "journal-article" @default.
• W2016099267 hasAuthorship W2016099267A5014915479 @default.
• W2016099267 hasAuthorship W2016099267A5026226353 @default.
• W2016099267 hasAuthorship W2016099267A5067908771 @default.
• W2016099267 hasAuthorship W2016099267A5090508228 @default.
• W2016099267 hasConcept C153356533 @default.
• W2016099267 hasConcept C166940927 @default.
• W2016099267 hasConcept C178790620 @default.
• W2016099267 hasConcept C183882617 @default.
• W2016099267 hasConcept C184651966 @default.
• W2016099267 hasConcept C185592680 @default.
• W2016099267 hasConcept C187428577 @default.
• W2016099267 hasConcept C188027245 @default.
• W2016099267 hasConcept C197471484 @default.
• W2016099267 hasConcept C2776371256 @default.
• W2016099267 hasConcept C3018358672 @default.
• W2016099267 hasConcept C4937899 @default.
• W2016099267 hasConcept C521977710 @default.
• W2016099267 hasConceptScore W2016099267C153356533 @default.
• W2016099267 hasConceptScore W2016099267C166940927 @default.

• next