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- W2016112382 abstract "Human placenta estradiol dehydrogenase (17β-hydroxysteroid:NAD(P)-oxidoreductase; EC 1.1.1.51) prepared with precautions to prevent subtle denaturation exhibits a concentration-dependent monomer-trimer transition. The kinetic properties of the enzyme show that the monomeric form of the protein can catalyze both net steroid dehydrogenation and substrate-mediated transhydrogenation. In contrast, the trimer catalyzes only substrate-mediated transhydrogenation. The trimerization is demonstrable by analysis of the kinetics, by gel permeation chromatography, and by density gradient ultracentrifugation." @default.
- W2016112382 created "2016-06-24" @default.
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- W2016112382 modified "2023-09-23" @default.
- W2016112382 title "Monomer-trimer transition of human placenta estradiol dehydrogenase" @default.
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- W2016112382 doi "https://doi.org/10.1016/0003-9861(69)90266-5" @default.
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