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- W2016113567 abstract "A variety of mechanisms have been demonstrated or suggested to explain the neutropenia that accompanies Felty's syndrome. This case report presents with Felty's syndrome with recurrent infections with initially had a clinical response to splenectomy. Eleven years later profound neutropenia recurred. In-vitro evidence for cell mediated autosensitisation of peripheral blood lymphocytes to autologous bone marrow cells was found. The cellular abnormalities improved after high-dose corticosteroids but not lithium. However, there did not appear to be a reduction in the incidence of clinical infections. The finding suggests that granulocytopenia in some patients with Felty's syndrome may be an autoimmune phenomenon." @default.
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- W2016113567 modified "2023-10-14" @default.
- W2016113567 title "Cell mediated autoimmune granulocytopenia in a case of Felty's syndrome." @default.
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- W2016113567 doi "https://doi.org/10.1136/ard.39.4.399" @default.
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