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- W2016113808 abstract "A 30–32S cytoplasmic iron-binding material has been detected in all fresh tissue and almost every malignant cell line in culture. It is absent from all diploid cell lines in culture and also from several non-diploid but contact inhibited lines. There is a good correlation between its absence and the accumulation of cytoplasmic autophagic vacuoles although no direct relationship between the two phenomena has been established. The cytoplasmic iron binding material labels with 55Fe both in vivo and in vitro. 65Zn and 45Ca either do not bind or they do not remain bound on sucrose gradients. The cIBM contains glucose as the only reducing sugar but neither isotopic glucose nor any other precursor thus far tried is incorporated. Various environmental perturbations markedly affect the levels of cytoplasmic iron binding material and the possible implications of these are discussed." @default.
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- W2016113808 title "An unusual cytoplasmic iron-binding material that disappears from diploid cells placed in culture" @default.
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- W2016113808 doi "https://doi.org/10.1016/0014-4827(74)90375-9" @default.
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