Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016114522> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2016114522 endingPage "5968" @default.
- W2016114522 startingPage "5962" @default.
- W2016114522 abstract "11α-Hydroxy-16α,17α-epoxyprogesterone (HEP) and 16α,17α-epoxy-progesterone (EP) are two isomorphic steroid pharmaceutical intermediates and form substitutional solid solution when crystallized from solution. In this paper, the crystallization process of HEP from different solution systems that comprise small amounts of EP was studied. The distribution coefficients of EP between crystal phase and solution phase were determined. The distribution of EP in two phases depends on the relative solubility of two steroids in the same solvent to a large extent. The crystal purity significantly increases with the increase of the relative solubility of the impurity (EP) to the primary solute (HEP) in the same solvent. The mixed solvent of toluene+chloroform was found to afford great purity enhancement for the studied steroid system. A simple linear relationship was observed between the distribution coefficients and the relative solubilities in the toluene+chloroform system." @default.
- W2016114522 created "2016-06-24" @default.
- W2016114522 creator A5017345150 @default.
- W2016114522 creator A5026746739 @default.
- W2016114522 creator A5085182130 @default.
- W2016114522 date "2006-09-01" @default.
- W2016114522 modified "2023-09-26" @default.
- W2016114522 title "Effect of solution thermodynamics on the purification of two isomorphic steroids by solution crystallization" @default.
- W2016114522 cites W1990692389 @default.
- W2016114522 cites W2005660304 @default.
- W2016114522 cites W2008333373 @default.
- W2016114522 cites W2032113135 @default.
- W2016114522 cites W2040006530 @default.
- W2016114522 cites W2059530451 @default.
- W2016114522 cites W2073285841 @default.
- W2016114522 cites W2123390993 @default.
- W2016114522 cites W2125337813 @default.
- W2016114522 cites W2328232244 @default.
- W2016114522 cites W2485560134 @default.
- W2016114522 cites W3020870217 @default.
- W2016114522 cites W4211068520 @default.
- W2016114522 doi "https://doi.org/10.1016/j.ces.2006.05.018" @default.
- W2016114522 hasPublicationYear "2006" @default.
- W2016114522 type Work @default.
- W2016114522 sameAs 2016114522 @default.
- W2016114522 citedByCount "13" @default.
- W2016114522 countsByYear W20161145222012 @default.
- W2016114522 countsByYear W20161145222018 @default.
- W2016114522 countsByYear W20161145222019 @default.
- W2016114522 countsByYear W20161145222021 @default.
- W2016114522 countsByYear W20161145222022 @default.
- W2016114522 countsByYear W20161145222023 @default.
- W2016114522 crossrefType "journal-article" @default.
- W2016114522 hasAuthorship W2016114522A5017345150 @default.
- W2016114522 hasAuthorship W2016114522A5026746739 @default.
- W2016114522 hasAuthorship W2016114522A5085182130 @default.
- W2016114522 hasConcept C121332964 @default.
- W2016114522 hasConcept C138999460 @default.
- W2016114522 hasConcept C155574463 @default.
- W2016114522 hasConcept C178790620 @default.
- W2016114522 hasConcept C185592680 @default.
- W2016114522 hasConcept C199360897 @default.
- W2016114522 hasConcept C203036418 @default.
- W2016114522 hasConcept C2778142098 @default.
- W2016114522 hasConcept C2780471494 @default.
- W2016114522 hasConcept C2781144210 @default.
- W2016114522 hasConcept C2781285689 @default.
- W2016114522 hasConcept C41008148 @default.
- W2016114522 hasConcept C43617362 @default.
- W2016114522 hasConcept C44280652 @default.
- W2016114522 hasConcept C71987851 @default.
- W2016114522 hasConcept C97355855 @default.
- W2016114522 hasConceptScore W2016114522C121332964 @default.
- W2016114522 hasConceptScore W2016114522C138999460 @default.
- W2016114522 hasConceptScore W2016114522C155574463 @default.
- W2016114522 hasConceptScore W2016114522C178790620 @default.
- W2016114522 hasConceptScore W2016114522C185592680 @default.
- W2016114522 hasConceptScore W2016114522C199360897 @default.
- W2016114522 hasConceptScore W2016114522C203036418 @default.
- W2016114522 hasConceptScore W2016114522C2778142098 @default.
- W2016114522 hasConceptScore W2016114522C2780471494 @default.
- W2016114522 hasConceptScore W2016114522C2781144210 @default.
- W2016114522 hasConceptScore W2016114522C2781285689 @default.
- W2016114522 hasConceptScore W2016114522C41008148 @default.
- W2016114522 hasConceptScore W2016114522C43617362 @default.
- W2016114522 hasConceptScore W2016114522C44280652 @default.
- W2016114522 hasConceptScore W2016114522C71987851 @default.
- W2016114522 hasConceptScore W2016114522C97355855 @default.
- W2016114522 hasIssue "18" @default.
- W2016114522 hasLocation W20161145221 @default.
- W2016114522 hasOpenAccess W2016114522 @default.
- W2016114522 hasPrimaryLocation W20161145221 @default.
- W2016114522 hasRelatedWork W150554982 @default.
- W2016114522 hasRelatedWork W1985695300 @default.
- W2016114522 hasRelatedWork W2013226422 @default.
- W2016114522 hasRelatedWork W2043405290 @default.
- W2016114522 hasRelatedWork W2094639770 @default.
- W2016114522 hasRelatedWork W2184210113 @default.
- W2016114522 hasRelatedWork W2332981743 @default.
- W2016114522 hasRelatedWork W2370117919 @default.
- W2016114522 hasRelatedWork W2613391298 @default.
- W2016114522 hasRelatedWork W3154247802 @default.
- W2016114522 hasVolume "61" @default.
- W2016114522 isParatext "false" @default.
- W2016114522 isRetracted "false" @default.
- W2016114522 magId "2016114522" @default.
- W2016114522 workType "article" @default.