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• W2016115765 abstract "Understanding the psychological mechanisms and underlying neurobiology of relapse behavior is essential for improving the treatment of addiction. Because the neurobiology of relapse behavior cannot be well studied in patients, we must rely on appropriate animal models. The alcohol deprivation effect (ADE) is a phenomenon in laboratory animals that models a relapse-like drinking situation, providing excellent face and predictive validity. In rodents, relapse-like behavior is largely influenced by the genetic make-up of an animal. It is not clear which other factors are responsible for variability of this behavior, but there seems to be no correlation between levels of baseline alcohol intake and the occurrence, duration, and robustness of the ADE. Rats that undergo long-term alcohol drinking for several months with repeated deprivation phases develop a compulsive drinking behavior during a relapse situation, characterized by insensitivity to taste adulteration with quinine, a loss of circadian drinking patterns during relapse-like drinking, and a shift toward drinking highly concentrated alcohol solutions to rapidly increase blood alcohol concentrations and achieve intoxication. Some mouse strains also exhibit an ADE, but this is usually of shorter duration than in rats. However, compulsive drinking in mice during a relapse situation has yet to be demonstrated. We extend our review section with original data showing that during long-term alcohol consumption, mice show a decline in alcohol intake, and the ADE fades with repeated deprivation phases. Furthermore, anti-relapse compounds that produce reliable effects on the ADE in rats produce paradoxical effects in mice. We conclude that the rat provides a better model system to study alcohol relapse and putative anti-relapse compounds." @default.
• W2016115765 created "2016-06-24" @default.
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• W2016115765 date "2014-05-01" @default.
• W2016115765 modified "2023-09-25" @default.
• W2016115765 title "The alcohol deprivation effect model for studying relapse behavior: A comparison between rats and mice" @default.
• W2016115765 cites W1526855917 @default.
• W2016115765 cites W1526856376 @default.
• W2016115765 cites W1571794072 @default.
• W2016115765 cites W1596152985 @default.
• W2016115765 cites W1875232603 @default.
• W2016115765 cites W1925405421 @default.
• W2016115765 cites W1934252933 @default.
• W2016115765 cites W1941761998 @default.
• W2016115765 cites W1964022477 @default.
• W2016115765 cites W1965406846 @default.
• W2016115765 cites W1967780293 @default.
• W2016115765 cites W1969636746 @default.
• W2016115765 cites W1969874126 @default.
• W2016115765 cites W1970137362 @default.
• W2016115765 cites W1971253434 @default.
• W2016115765 cites W1971690120 @default.
• W2016115765 cites W1972687616 @default.
• W2016115765 cites W1976804981 @default.
• W2016115765 cites W1989822821 @default.
• W2016115765 cites W1992208327 @default.
• W2016115765 cites W2000275624 @default.
• W2016115765 cites W2000347039 @default.
• W2016115765 cites W2004019101 @default.
• W2016115765 cites W2006511742 @default.
• W2016115765 cites W2009731041 @default.
• W2016115765 cites W2013536737 @default.
• W2016115765 cites W2018284650 @default.
• W2016115765 cites W2021136584 @default.
• W2016115765 cites W2024485135 @default.
• W2016115765 cites W2028528911 @default.
• W2016115765 cites W2028537662 @default.
• W2016115765 cites W2030182465 @default.
• W2016115765 cites W2030725063 @default.
• W2016115765 cites W2034205729 @default.
• W2016115765 cites W2037163473 @default.
• W2016115765 cites W2038064315 @default.
• W2016115765 cites W2040410932 @default.
• W2016115765 cites W2042119083 @default.
• W2016115765 cites W2043701877 @default.
• W2016115765 cites W2045683693 @default.
• W2016115765 cites W2046964321 @default.
• W2016115765 cites W2060922794 @default.
• W2016115765 cites W2069544353 @default.
• W2016115765 cites W2078538386 @default.
• W2016115765 cites W2090924863 @default.
• W2016115765 cites W2091474137 @default.
• W2016115765 cites W2092297027 @default.
• W2016115765 cites W2093046117 @default.
• W2016115765 cites W2094614798 @default.
• W2016115765 cites W2103133893 @default.
• W2016115765 cites W2109064970 @default.
• W2016115765 cites W2109366273 @default.
• W2016115765 cites W2112323466 @default.
• W2016115765 cites W2112606475 @default.
• W2016115765 cites W2113262711 @default.
• W2016115765 cites W2117461455 @default.
• W2016115765 cites W2119197510 @default.
• W2016115765 cites W2122807925 @default.
• W2016115765 cites W2137899470 @default.
• W2016115765 cites W2153773787 @default.
• W2016115765 cites W2158282570 @default.
• W2016115765 cites W2159077908 @default.
• W2016115765 cites W2161798290 @default.
• W2016115765 cites W2227734542 @default.
• W2016115765 cites W2279564409 @default.
• W2016115765 cites W247003012 @default.
• W2016115765 cites W3019801591 @default.
• W2016115765 cites W4213265599 @default.
• W2016115765 cites W4233780223 @default.
• W2016115765 cites W4236260884 @default.
• W2016115765 cites W4246621913 @default.
• W2016115765 cites W4375213111 @default.
• W2016115765 doi "https://doi.org/10.1016/j.alcohol.2014.03.002" @default.
• W2016115765 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24811155" @default.
• W2016115765 hasPublicationYear "2014" @default.
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