FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016118439> ?p ?o ?g. }

• W2016118439 endingPage "188" @default.
• W2016118439 startingPage "181" @default.
• W2016118439 abstract "Objective Oral estrogens reduce asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, and an independent risk factor for cardiovascular disease. This study was conducted to compare the effect on ADMA between intranasal and oral 17β-estradiol (E2) combined with norethisterone (acetate) (NET(A)) administration in postmenopausal women. Methods In a two-center, randomized, double-blind, comparative study 90 healthy postmenopausal women (age 56.6 ± 4.7 years) received daily continuous combined intranasal E2/NET 175 μg/275 μg (n = 47) or oral E2/NETA 1 mg/0.5 mg (n = 43) for one year. At baseline, week 12 and 52, plasma concentrations of ADMA, arginine and symmetric dimethylarginine (SDMA) were measured by high-performance liquid chromatography. Results Oral E2/NETA reduced ADMA concentrations (−7.4%; 95% confidence interval (CI) −10.4 to −4.4%), while intranasal E2/NET had no effect (−0.8%; 95% CI −3.7 to 2.1%) after 52 weeks. In both groups, arginine was transiently decreased compared to baseline at week 12 (intranasal: −6.1%; 95% CI −9.1 to −3.0%; oral: −6.5%; 95% CI −10.9 to −2.1%). Only oral E2/NETA reduced SDMA concentrations. Conclusions Oral administration of E2/NETA reduced ADMA and SDMA concentrations, whereas intranasal administration did not. Both treatments transiently reduced arginine. The decrease in ADMA by oral estrogens could be a key phenomenon in the modulation of nitric oxide synthesis by postmenopausal hormone therapy." @default.
• W2016118439 created "2016-06-24" @default.
• W2016118439 creator A5027467733 @default.
• W2016118439 creator A5045835727 @default.
• W2016118439 creator A5051093536 @default.
• W2016118439 creator A5051560890 @default.
• W2016118439 creator A5086090905 @default.
• W2016118439 date "2007-11-01" @default.
• W2016118439 modified "2023-09-27" @default.
• W2016118439 title "Effects of intranasal versus oral hormone therapy on asymmetric dimethylarginine in healthy postmenopausal women: A randomized study" @default.
• W2016118439 cites W1968141837 @default.
• W2016118439 cites W1974041941 @default.
• W2016118439 cites W1976879422 @default.
• W2016118439 cites W1981922048 @default.
• W2016118439 cites W1987609221 @default.
• W2016118439 cites W1991875255 @default.
• W2016118439 cites W1996891236 @default.
• W2016118439 cites W1997640957 @default.
• W2016118439 cites W2001038193 @default.
• W2016118439 cites W2017891821 @default.
• W2016118439 cites W2024480273 @default.
• W2016118439 cites W2036975691 @default.
• W2016118439 cites W2041493084 @default.
• W2016118439 cites W2042053234 @default.
• W2016118439 cites W2045866397 @default.
• W2016118439 cites W2050369644 @default.
• W2016118439 cites W2068090109 @default.
• W2016118439 cites W2077402657 @default.
• W2016118439 cites W2084669626 @default.
• W2016118439 cites W2113264115 @default.
• W2016118439 cites W2113657333 @default.
• W2016118439 cites W2119177204 @default.
• W2016118439 cites W2124925925 @default.
• W2016118439 cites W2142544745 @default.
• W2016118439 cites W2142559019 @default.
• W2016118439 cites W2148531805 @default.
• W2016118439 cites W2165481492 @default.
• W2016118439 cites W2166937516 @default.
• W2016118439 cites W2166969544 @default.
• W2016118439 cites W2169513794 @default.
• W2016118439 cites W2170563960 @default.
• W2016118439 cites W2328664855 @default.
• W2016118439 cites W2762603006 @default.
• W2016118439 doi "https://doi.org/10.1016/j.atherosclerosis.2006.09.018" @default.
• W2016118439 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17084844" @default.
• W2016118439 hasPublicationYear "2007" @default.
• W2016118439 type Work @default.
• W2016118439 sameAs 2016118439 @default.
• W2016118439 citedByCount "11" @default.
• W2016118439 countsByYear W20161184392013 @default.
• W2016118439 countsByYear W20161184392016 @default.
• W2016118439 countsByYear W20161184392018 @default.
• W2016118439 countsByYear W20161184392020 @default.
• W2016118439 crossrefType "journal-article" @default.
• W2016118439 hasAuthorship W2016118439A5027467733 @default.
• W2016118439 hasAuthorship W2016118439A5045835727 @default.
• W2016118439 hasAuthorship W2016118439A5051093536 @default.
• W2016118439 hasAuthorship W2016118439A5051560890 @default.
• W2016118439 hasAuthorship W2016118439A5086090905 @default.
• W2016118439 hasConcept C126322002 @default.
• W2016118439 hasConcept C134018914 @default.
• W2016118439 hasConcept C185592680 @default.
• W2016118439 hasConcept C2777056448 @default.
• W2016118439 hasConcept C2777468819 @default.
• W2016118439 hasConcept C2779279991 @default.
• W2016118439 hasConcept C2779877776 @default.
• W2016118439 hasConcept C2780159708 @default.
• W2016118439 hasConcept C2780835420 @default.
• W2016118439 hasConcept C2781039349 @default.
• W2016118439 hasConcept C2908647359 @default.
• W2016118439 hasConcept C2986817661 @default.
• W2016118439 hasConcept C44249647 @default.
• W2016118439 hasConcept C515207424 @default.
• W2016118439 hasConcept C519581460 @default.
• W2016118439 hasConcept C55493867 @default.
• W2016118439 hasConcept C71315377 @default.
• W2016118439 hasConcept C71924100 @default.
• W2016118439 hasConcept C85663871 @default.
• W2016118439 hasConcept C98274493 @default.
• W2016118439 hasConcept C99454951 @default.
• W2016118439 hasConceptScore W2016118439C126322002 @default.
• W2016118439 hasConceptScore W2016118439C134018914 @default.
• W2016118439 hasConceptScore W2016118439C185592680 @default.
• W2016118439 hasConceptScore W2016118439C2777056448 @default.
• W2016118439 hasConceptScore W2016118439C2777468819 @default.
• W2016118439 hasConceptScore W2016118439C2779279991 @default.
• W2016118439 hasConceptScore W2016118439C2779877776 @default.
• W2016118439 hasConceptScore W2016118439C2780159708 @default.
• W2016118439 hasConceptScore W2016118439C2780835420 @default.
• W2016118439 hasConceptScore W2016118439C2781039349 @default.
• W2016118439 hasConceptScore W2016118439C2908647359 @default.
• W2016118439 hasConceptScore W2016118439C2986817661 @default.
• W2016118439 hasConceptScore W2016118439C44249647 @default.
• W2016118439 hasConceptScore W2016118439C515207424 @default.
• W2016118439 hasConceptScore W2016118439C519581460 @default.
• W2016118439 hasConceptScore W2016118439C55493867 @default.
• W2016118439 hasConceptScore W2016118439C71315377 @default.
• W2016118439 hasConceptScore W2016118439C71924100 @default.

• next