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- W2016118895 abstract "Attack upon an anesthetized rat was induced in cats by electrical stimulation of the perifornical region of the midlateral hypothalamus. Attack thresholds and current-latency relationships were determined before and after imipramine, iprindole. Lu 3010 {;3,3-dimethyl-l-[3-methyl-amino) propyl]-l-phenyl-phthalan HC1};, chlorpromazine and atropine. Imipramine produced suppression of attack behavior at a calculated ED50 of 8.5 mg/kg. Hiss response to stimulation, though not obtained in all cats, was not suppressed by imipramine. The other agents failed to block stimulus-bound attack. Blockade of attack by imipramine may be due to its limbic system depressant effects." @default.
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- W2016118895 title "The effect of imipramine and selected drugs on attack elicited by hypothalamic stimulation in the cat" @default.
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- W2016118895 doi "https://doi.org/10.1016/0028-3908(71)90019-0" @default.
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