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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016123744> ?p ?o ?g. }

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• W2016123744 abstract "Yang et al. have isolated from bovine brain an octapeptide, FLFQPQRF-NH2 (F-8-F-NH2), with certain antiopiate properties. Malin et al. previously found that ICV injection of this peptide could precipitate an opiate abstinence syndrome in dependent rats. RIA revealed significantly higher levels of F-8-F-NH2 immunoreactivity in CSF withdrawn from the cisterna magna of morphine-dependent rats as opposed to CSF withdrawn from sham-implanted controls. ICV infusion of IgG from antiserum against F-8-F-NH2 significantly reduced the number of abstinence signs subsequently precipitated by naloxone in morphine-dependent rats." @default.
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• W2016123744 date "1990-09-01" @default.
• W2016123744 modified "2023-10-02" @default.
• W2016123744 title "FMRF-NH2-like mammalian octapeptide: Possible role in opiate dependence and abstinence" @default.
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• W2016123744 doi "https://doi.org/10.1016/0196-9781(90)90018-z" @default.
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