FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016127775> ?p ?o ?g. }

• W2016127775 endingPage "628" @default.
• W2016127775 startingPage "624" @default.
• W2016127775 abstract "Several in vitro and in vivo studies have emphasized the importance of generating a high inspiratory flow when using a dry powder inhaler. Little attention has been paid to the influence of the inspiratory flow profile on the particle size distribution contained in aerosols generated by these devices. The internal volume of a device such as the Turbuhaler is small compared with a vital capacity breath and it is possible that all the powder has been drawn from the device before peak inspiratory flow has been achieved, particularly if the time to peak inspiratory flow is prolonged. A series of experiments were performed to assess the effect of different flow profiles through the Turbuhaler, each with a peak flow of 60 1 min-1. A 400 microgram budesonide Turbuhaler was enclosed in a chamber allowing air to pass unimpeded through the dosing channels and entrainment ports. A large three-way tap was used to blow powder from the device across a Malvern Mastersizer laser particle sizer which produced a profile of the particle size distribution within the aerosol. The rate of increase in flow through the Turbuhaler was determined by the rate at which the three-way tap was turned, and recorded by means of a pneumotachograph. The rate of increase in flow was found to significantly affect the particle size-distribution within the aerosol. Failure to attain a flow of 30 1 min-1 before 150 ml of air had passed through the device resulted in the aerosol volume median diameter increasing from less than 6.6 microns to greater than 45.3 microns. These results indicate that flow during the initial part of the inspiratory effort may be important in determining the characteristics of the aerosol generated by a dry powder inhaler. With more sophisticated equipment, it might be possible to explore the relationship between flow profile and particle size distribution generated by dry powder devices in more detail." @default.
• W2016127775 created "2016-06-24" @default.
• W2016127775 creator A5035094674 @default.
• W2016127775 creator A5041041126 @default.
• W2016127775 creator A5076450145 @default.
• W2016127775 date "1997-11-01" @default.
• W2016127775 modified "2023-10-03" @default.
• W2016127775 title "Flow early in the inspiratory manoeuvre affects the aerosol particle size distribution from a Turbuhaler" @default.
• W2016127775 cites W1998433520 @default.
• W2016127775 cites W2019943332 @default.
• W2016127775 cites W2026766056 @default.
• W2016127775 cites W2029054288 @default.
• W2016127775 cites W2083436179 @default.
• W2016127775 cites W2087887687 @default.
• W2016127775 cites W2097470033 @default.
• W2016127775 cites W2115309284 @default.
• W2016127775 cites W2177542949 @default.
• W2016127775 doi "https://doi.org/10.1016/s0954-6111(97)90009-3" @default.
• W2016127775 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9488896" @default.
• W2016127775 hasPublicationYear "1997" @default.
• W2016127775 type Work @default.
• W2016127775 sameAs 2016127775 @default.
• W2016127775 citedByCount "122" @default.
• W2016127775 countsByYear W20161277752012 @default.
• W2016127775 countsByYear W20161277752013 @default.
• W2016127775 countsByYear W20161277752014 @default.
• W2016127775 countsByYear W20161277752015 @default.
• W2016127775 countsByYear W20161277752016 @default.
• W2016127775 countsByYear W20161277752017 @default.
• W2016127775 countsByYear W20161277752018 @default.
• W2016127775 countsByYear W20161277752019 @default.
• W2016127775 countsByYear W20161277752020 @default.
• W2016127775 countsByYear W20161277752021 @default.
• W2016127775 countsByYear W20161277752022 @default.
• W2016127775 countsByYear W20161277752023 @default.
• W2016127775 crossrefType "journal-article" @default.
• W2016127775 hasAuthorship W2016127775A5035094674 @default.
• W2016127775 hasAuthorship W2016127775A5041041126 @default.
• W2016127775 hasAuthorship W2016127775A5076450145 @default.
• W2016127775 hasBestOaLocation W20161277751 @default.
• W2016127775 hasConcept C111368507 @default.
• W2016127775 hasConcept C121332964 @default.
• W2016127775 hasConcept C126322002 @default.
• W2016127775 hasConcept C127313418 @default.
• W2016127775 hasConcept C136229726 @default.
• W2016127775 hasConcept C147789679 @default.
• W2016127775 hasConcept C153294291 @default.
• W2016127775 hasConcept C172120300 @default.
• W2016127775 hasConcept C185592680 @default.
• W2016127775 hasConcept C187530423 @default.
• W2016127775 hasConcept C192562407 @default.
• W2016127775 hasConcept C27101514 @default.
• W2016127775 hasConcept C2776042228 @default.
• W2016127775 hasConcept C2777419714 @default.
• W2016127775 hasConcept C2777714996 @default.
• W2016127775 hasConcept C2778517922 @default.
• W2016127775 hasConcept C2779345167 @default.
• W2016127775 hasConcept C2780261241 @default.
• W2016127775 hasConcept C2908933175 @default.
• W2016127775 hasConcept C42219234 @default.
• W2016127775 hasConcept C57879066 @default.
• W2016127775 hasConcept C60448018 @default.
• W2016127775 hasConcept C71924100 @default.
• W2016127775 hasConceptScore W2016127775C111368507 @default.
• W2016127775 hasConceptScore W2016127775C121332964 @default.
• W2016127775 hasConceptScore W2016127775C126322002 @default.
• W2016127775 hasConceptScore W2016127775C127313418 @default.
• W2016127775 hasConceptScore W2016127775C136229726 @default.
• W2016127775 hasConceptScore W2016127775C147789679 @default.
• W2016127775 hasConceptScore W2016127775C153294291 @default.
• W2016127775 hasConceptScore W2016127775C172120300 @default.
• W2016127775 hasConceptScore W2016127775C185592680 @default.
• W2016127775 hasConceptScore W2016127775C187530423 @default.
• W2016127775 hasConceptScore W2016127775C192562407 @default.
• W2016127775 hasConceptScore W2016127775C27101514 @default.
• W2016127775 hasConceptScore W2016127775C2776042228 @default.
• W2016127775 hasConceptScore W2016127775C2777419714 @default.
• W2016127775 hasConceptScore W2016127775C2777714996 @default.
• W2016127775 hasConceptScore W2016127775C2778517922 @default.
• W2016127775 hasConceptScore W2016127775C2779345167 @default.
• W2016127775 hasConceptScore W2016127775C2780261241 @default.
• W2016127775 hasConceptScore W2016127775C2908933175 @default.
• W2016127775 hasConceptScore W2016127775C42219234 @default.
• W2016127775 hasConceptScore W2016127775C57879066 @default.
• W2016127775 hasConceptScore W2016127775C60448018 @default.
• W2016127775 hasConceptScore W2016127775C71924100 @default.
• W2016127775 hasIssue "10" @default.
• W2016127775 hasLocation W20161277751 @default.
• W2016127775 hasLocation W20161277752 @default.
• W2016127775 hasOpenAccess W2016127775 @default.
• W2016127775 hasPrimaryLocation W20161277751 @default.
• W2016127775 hasRelatedWork W1673769914 @default.
• W2016127775 hasRelatedWork W1999944868 @default.
• W2016127775 hasRelatedWork W2038742552 @default.
• W2016127775 hasRelatedWork W2064180869 @default.
• W2016127775 hasRelatedWork W2107498419 @default.
• W2016127775 hasRelatedWork W2107675676 @default.
• W2016127775 hasRelatedWork W2155687527 @default.

• next