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• W2016129299 abstract "Numerous studies have identified clinically important predictors of early mortality and prognosis. Scoring systems have been devised, including the Norris score, 1 Norris R.M. Brandt P.W.T. Caughey D.E. Lee A.J. Scott P.J. A new coronary prognostic index. Lancet. 1969; 1: 274-278 Abstract PubMed Google Scholar Killip class, 2 Killip T. Kimball J.T. Treatment of myocardial infarction in a coronary care unit a two year experience with 250 patients. Am J Cardiol. 1967; 20: 457-464 Abstract Full Text PDF PubMed Scopus (1667) Google Scholar Chapman index, 3 Chapman B.L. Gray C.H. Prognostic index for myocardial infarction treated in a coronary care unit. Br Heart J. 1973; 35: 135-141 Crossref PubMed Scopus (30) Google Scholar and Dubois index. 4 Dubois C. Pierard L.A. Albert A. Smeets J.-P. Demoulin J.-C. Boland J. Kulbertus H.E. Short-term risk stratification at admission based on simple clinical data in acute myocardial infarction. Am J Cardiol. 1988; 61: 216-219 Abstract Full Text PDF PubMed Scopus (50) Google Scholar Patient age and evidence of left ventricular (LV) dysfunction have been consistently associated with mortality. The latter has been assessed clinically, by chest x-ray, and by echocardiography or angiography. The Norris score was published in 1969 as “a new coronary prognostic index” 1 Norris R.M. Brandt P.W.T. Caughey D.E. Lee A.J. Scott P.J. A new coronary prognostic index. Lancet. 1969; 1: 274-278 Abstract PubMed Google Scholar and was constructed from data gathered during an earlier study of in-hospital mortality from acute myocardial infarction (AMI). 5 Norris R.M. Bensley K.E. Caughey D.E. Scott P.J. Hospital mortality in acute myocardial infarction. Br Med J. 1968; 3: 143-146 Crossref PubMed Scopus (23) Google Scholar Using discriminant analysis, the authors created an index based on 6 factors associated with in-hospital mortality. These were age, electrocardiographic site of AMI, admission systolic blood pressure, radiographic heart size, appearance of the lung fields, and previous ischemia. The mortality predicted by the index was derived from the mortality observed by Norris and coworkers. 1 Norris R.M. Brandt P.W.T. Caughey D.E. Lee A.J. Scott P.J. A new coronary prognostic index. Lancet. 1969; 1: 274-278 Abstract PubMed Google Scholar The score was used and validated in a subsequent investigation of the impact of the coronary care unit on mortality 6 Norris R.M. Lee A.J. Brandt P.W.T. Mortality in a coronary care unit analysed by a new coronary prognostic index. Lancet. 1969; 1: 278-281 Abstract PubMed Google Scholar and has remained probably the best-known prognostic index. The data used are available in almost all patients, but the score has proved overly complex for routine use. We postulated that previous scoring systems for predicting in-hospital mortality, particularly the Norris score, no longer are applicable in an era of emergency coronary reperfusion and declining mortality. We also postulated that the single measure of LV ejection fraction (EF) would contain significant prognostic information, and that this might replace the other indirect measures of LV dysfunction in the Norris score. If the EF, as we expected, was predictive of early mortality, then a simplified scoring system could be developed. This retrospective study reappraises the Norris score and assesses the relative prognostic value of key clinical variables, including EF, in patients with AMI." @default.
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• W2016129299 title "Reappraisal of the Norris score and the prognostic value of left ventricular ejection fraction measurement for in-hospital mortality after acute myocardial infarction" @default.
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• W2016129299 doi "https://doi.org/10.1016/s0002-9149(98)00919-9" @default.
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