FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016136675> ?p ?o ?g. }

• W2016136675 endingPage "308" @default.
• W2016136675 startingPage "304" @default.
• W2016136675 abstract "Human blood neutrophils (PMN) rapidly release arachidonic acid (AA) from cellular phospholipids when stimulatedin vitrowith a variety of inflammatory agonists. Free AA is then metabolized via 5′-lipoxygenase to produce bioactive mediators such as leukotriene B4and 5-hydroxyeicosatetraenoate. Arachidonic acid can also be metabolized via the cyclooxygenase or prostaglandin G/H synthase (PGHS) pathway to form prostaglandins and thromboxane. We show here that human blood PMN express the PGHS 2 gene when stimulated with bacterial lipopolysaccharide (LPS). PGHS 2 mRNA increases within 30 min after LPS stimulation and PGHS 2 immunoreactive protein is detectable by 5 h. Although PGHS 1 mRNA is detectable in PMN, no immunoreactive protein is observed in either resting or LPS-stimulated cells. Following stimulation with LPS and expression of PGHS 2, PMN increase secretion of prostaglandin E2. This phenotypic change in PMN could be an important mechanism for regulating inflammation." @default.
• W2016136675 created "2016-06-24" @default.
• W2016136675 creator A5039239605 @default.
• W2016136675 creator A5047444154 @default.
• W2016136675 creator A5051164039 @default.
• W2016136675 date "1998-06-01" @default.
• W2016136675 modified "2023-09-27" @default.
• W2016136675 title "Human Neutrophils Express the Prostaglandin G/H Synthase 2 Gene When Stimulated with Bacterial Lipopolysaccharide" @default.
• W2016136675 cites W1540849804 @default.
• W2016136675 cites W1542295311 @default.
• W2016136675 cites W1574290496 @default.
• W2016136675 cites W1579134710 @default.
• W2016136675 cites W1587123510 @default.
• W2016136675 cites W1881438746 @default.
• W2016136675 cites W1997861448 @default.
• W2016136675 cites W2020711329 @default.
• W2016136675 cites W2026457555 @default.
• W2016136675 cites W2026732117 @default.
• W2016136675 cites W2054917172 @default.
• W2016136675 cites W2065248129 @default.
• W2016136675 cites W2075836508 @default.
• W2016136675 cites W2081822067 @default.
• W2016136675 cites W2108661128 @default.
• W2016136675 cites W2128285805 @default.
• W2016136675 cites W2146954585 @default.
• W2016136675 cites W2158686638 @default.
• W2016136675 cites W2161033554 @default.
• W2016136675 cites W4254962641 @default.
• W2016136675 doi "https://doi.org/10.1006/clin.1998.4545" @default.
• W2016136675 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9646841" @default.
• W2016136675 hasPublicationYear "1998" @default.
• W2016136675 type Work @default.
• W2016136675 sameAs 2016136675 @default.
• W2016136675 citedByCount "23" @default.
• W2016136675 countsByYear W20161366752012 @default.
• W2016136675 countsByYear W20161366752016 @default.
• W2016136675 countsByYear W20161366752018 @default.
• W2016136675 countsByYear W20161366752022 @default.
• W2016136675 countsByYear W20161366752023 @default.
• W2016136675 crossrefType "journal-article" @default.
• W2016136675 hasAuthorship W2016136675A5039239605 @default.
• W2016136675 hasAuthorship W2016136675A5047444154 @default.
• W2016136675 hasAuthorship W2016136675A5051164039 @default.
• W2016136675 hasConcept C126322002 @default.
• W2016136675 hasConcept C134018914 @default.
• W2016136675 hasConcept C170493617 @default.
• W2016136675 hasConcept C181199279 @default.
• W2016136675 hasConcept C185592680 @default.
• W2016136675 hasConcept C203014093 @default.
• W2016136675 hasConcept C24998067 @default.
• W2016136675 hasConcept C2776042228 @default.
• W2016136675 hasConcept C2776352991 @default.
• W2016136675 hasConcept C2776452501 @default.
• W2016136675 hasConcept C2776914184 @default.
• W2016136675 hasConcept C2777956040 @default.
• W2016136675 hasConcept C2778078955 @default.
• W2016136675 hasConcept C2778754761 @default.
• W2016136675 hasConcept C2779689624 @default.
• W2016136675 hasConcept C2780664492 @default.
• W2016136675 hasConcept C2780857362 @default.
• W2016136675 hasConcept C2781024287 @default.
• W2016136675 hasConcept C2781080829 @default.
• W2016136675 hasConcept C49039625 @default.
• W2016136675 hasConcept C55493867 @default.
• W2016136675 hasConcept C71924100 @default.
• W2016136675 hasConcept C86803240 @default.
• W2016136675 hasConcept C89560881 @default.
• W2016136675 hasConceptScore W2016136675C126322002 @default.
• W2016136675 hasConceptScore W2016136675C134018914 @default.
• W2016136675 hasConceptScore W2016136675C170493617 @default.
• W2016136675 hasConceptScore W2016136675C181199279 @default.
• W2016136675 hasConceptScore W2016136675C185592680 @default.
• W2016136675 hasConceptScore W2016136675C203014093 @default.
• W2016136675 hasConceptScore W2016136675C24998067 @default.
• W2016136675 hasConceptScore W2016136675C2776042228 @default.
• W2016136675 hasConceptScore W2016136675C2776352991 @default.
• W2016136675 hasConceptScore W2016136675C2776452501 @default.
• W2016136675 hasConceptScore W2016136675C2776914184 @default.
• W2016136675 hasConceptScore W2016136675C2777956040 @default.
• W2016136675 hasConceptScore W2016136675C2778078955 @default.
• W2016136675 hasConceptScore W2016136675C2778754761 @default.
• W2016136675 hasConceptScore W2016136675C2779689624 @default.
• W2016136675 hasConceptScore W2016136675C2780664492 @default.
• W2016136675 hasConceptScore W2016136675C2780857362 @default.
• W2016136675 hasConceptScore W2016136675C2781024287 @default.
• W2016136675 hasConceptScore W2016136675C2781080829 @default.
• W2016136675 hasConceptScore W2016136675C49039625 @default.
• W2016136675 hasConceptScore W2016136675C55493867 @default.
• W2016136675 hasConceptScore W2016136675C71924100 @default.
• W2016136675 hasConceptScore W2016136675C86803240 @default.
• W2016136675 hasConceptScore W2016136675C89560881 @default.
• W2016136675 hasIssue "3" @default.
• W2016136675 hasLocation W20161366751 @default.
• W2016136675 hasLocation W20161366752 @default.
• W2016136675 hasOpenAccess W2016136675 @default.
• W2016136675 hasPrimaryLocation W20161366751 @default.
• W2016136675 hasRelatedWork W1992865522 @default.
• W2016136675 hasRelatedWork W1996051072 @default.

• next