FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016154138> ?p ?o ?g. }

• W2016154138 endingPage "59" @default.
• W2016154138 startingPage "53" @default.
• W2016154138 abstract "Ethylenethiourea (ETU) is of major toxicological concern, since in experimental animal studies, ETU has shown a large spectrum of adverse effects. High occupational exposure can be found among agricultural workers or during manufacturing of ethylenbisdithiocarbamates (EBDC). For the general public, sources of environmental exposure may be residues of ETU in commercial products, food and beverages. For the determination of ETU in human urine we present a high-throughput online on-column extraction liquid chromatography triple quadrupole mass spectrometry method using direct injection of hydrolysed urine samples. This method is simple, user- and environmentally friendly and all sample preparation is performed in 96-well plates. A labelled ETU internal standard was used for quantification. The method showed a good sensitivity with a limit of quantification (LOQ) of 0.5ng ETU/mL urine and the calibration curve was linear in the range 0.25-200ng ETU/mL urine. The within-run, between-run and between-batch precision was between 6% and 13%. Alkaline hydrolysis considerably increased the levels of ETU indicating a potential conjugate. The method was applied in an experimental dermal exposure study in humans, with sample concentrations ranging from 0.4 to 5.0ng ETU/mL urine. The excretion in urine was 10% of the applied dose. The elimination profile seemed to differ between the two individuals. The results show an estimated half-life of ETU between 34 and 72h. Although the experiment is limited to two individuals, the data provide valuable and new information regarding the toxicokinetics of ETU after dermal exposure." @default.
• W2016154138 created "2016-06-24" @default.
• W2016154138 creator A5004251967 @default.
• W2016154138 creator A5015463243 @default.
• W2016154138 creator A5071384333 @default.
• W2016154138 creator A5077053822 @default.
• W2016154138 creator A5084946593 @default.
• W2016154138 date "2013-09-01" @default.
• W2016154138 modified "2023-10-16" @default.
• W2016154138 title "High-throughput method for the analysis of ethylenethiourea with direct injection of hydrolysed urine using online on-column extraction liquid chromatography and triple quadrupole mass spectrometry" @default.
• W2016154138 cites W1819047058 @default.
• W2016154138 cites W1964102223 @default.
• W2016154138 cites W1964922020 @default.
• W2016154138 cites W1965060487 @default.
• W2016154138 cites W1974149498 @default.
• W2016154138 cites W1980852410 @default.
• W2016154138 cites W1980950470 @default.
• W2016154138 cites W1984028352 @default.
• W2016154138 cites W1986423905 @default.
• W2016154138 cites W1992612177 @default.
• W2016154138 cites W1995820416 @default.
• W2016154138 cites W2008088030 @default.
• W2016154138 cites W2014897596 @default.
• W2016154138 cites W2018561123 @default.
• W2016154138 cites W2019212855 @default.
• W2016154138 cites W2029329498 @default.
• W2016154138 cites W2040237777 @default.
• W2016154138 cites W2050737382 @default.
• W2016154138 cites W2055877588 @default.
• W2016154138 cites W2059069686 @default.
• W2016154138 cites W2068684751 @default.
• W2016154138 cites W2083308115 @default.
• W2016154138 cites W2089601744 @default.
• W2016154138 cites W2093394303 @default.
• W2016154138 cites W2118385936 @default.
• W2016154138 cites W2128254781 @default.
• W2016154138 cites W2133302351 @default.
• W2016154138 cites W2133512508 @default.
• W2016154138 cites W2168150747 @default.
• W2016154138 cites W4211086477 @default.
• W2016154138 doi "https://doi.org/10.1016/j.jchromb.2013.06.035" @default.
• W2016154138 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23896430" @default.
• W2016154138 hasPublicationYear "2013" @default.
• W2016154138 type Work @default.
• W2016154138 sameAs 2016154138 @default.
• W2016154138 citedByCount "23" @default.
• W2016154138 countsByYear W20161541382013 @default.
• W2016154138 countsByYear W20161541382014 @default.
• W2016154138 countsByYear W20161541382016 @default.
• W2016154138 countsByYear W20161541382018 @default.
• W2016154138 countsByYear W20161541382019 @default.
• W2016154138 countsByYear W20161541382020 @default.
• W2016154138 countsByYear W20161541382021 @default.
• W2016154138 countsByYear W20161541382022 @default.
• W2016154138 countsByYear W20161541382023 @default.
• W2016154138 crossrefType "journal-article" @default.
• W2016154138 hasAuthorship W2016154138A5004251967 @default.
• W2016154138 hasAuthorship W2016154138A5015463243 @default.
• W2016154138 hasAuthorship W2016154138A5071384333 @default.
• W2016154138 hasAuthorship W2016154138A5077053822 @default.
• W2016154138 hasAuthorship W2016154138A5084946593 @default.
• W2016154138 hasBestOaLocation W20161541381 @default.
• W2016154138 hasConcept C119128265 @default.
• W2016154138 hasConcept C162356407 @default.
• W2016154138 hasConcept C172493649 @default.
• W2016154138 hasConcept C185592680 @default.
• W2016154138 hasConcept C23531484 @default.
• W2016154138 hasConcept C2778576202 @default.
• W2016154138 hasConcept C2780026642 @default.
• W2016154138 hasConcept C31827203 @default.
• W2016154138 hasConcept C43617362 @default.
• W2016154138 hasConcept C4725764 @default.
• W2016154138 hasConcept C55493867 @default.
• W2016154138 hasConcept C64489805 @default.
• W2016154138 hasConcept C71043704 @default.
• W2016154138 hasConceptScore W2016154138C119128265 @default.
• W2016154138 hasConceptScore W2016154138C162356407 @default.
• W2016154138 hasConceptScore W2016154138C172493649 @default.
• W2016154138 hasConceptScore W2016154138C185592680 @default.
• W2016154138 hasConceptScore W2016154138C23531484 @default.
• W2016154138 hasConceptScore W2016154138C2778576202 @default.
• W2016154138 hasConceptScore W2016154138C2780026642 @default.
• W2016154138 hasConceptScore W2016154138C31827203 @default.
• W2016154138 hasConceptScore W2016154138C43617362 @default.
• W2016154138 hasConceptScore W2016154138C4725764 @default.
• W2016154138 hasConceptScore W2016154138C55493867 @default.
• W2016154138 hasConceptScore W2016154138C64489805 @default.
• W2016154138 hasConceptScore W2016154138C71043704 @default.
• W2016154138 hasFunder F4320321032 @default.
• W2016154138 hasFunder F4320321033 @default.
• W2016154138 hasFunder F4320322579 @default.
• W2016154138 hasFunder F4320326012 @default.
• W2016154138 hasLocation W20161541381 @default.
• W2016154138 hasLocation W20161541382 @default.
• W2016154138 hasOpenAccess W2016154138 @default.
• W2016154138 hasPrimaryLocation W20161541381 @default.
• W2016154138 hasRelatedWork W1950305724 @default.
• W2016154138 hasRelatedWork W1973261120 @default.

• next