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- W2016156790 abstract "The purpose of this study was to ascertain the effects of the skull on the location, shape and power of the acoustic field produced by a 150 mm radius hemispherical array operating at 220 kHz. We wanted to determine whether phase aberrations were significant at this frequency, the amount of attenuation, and whether CT data could be predictive of the trans-skull field. The effects of five calvaria were evaluated. Acoustic field data and CT scans for each skull specimen were imported into MATLAB® for measurements and visualization in two and three dimensions. We examined the effects of skull density, porosity, thickness, and sonication incident angles, and estimated the relative contributions of longitudinal and shear transmission to the total transmitted power. Power transmission through the skulls varied between 4% and 23% (mean: 12%). The range of focal position shifts was from 0.50 mm to 4.32 mm (mean: 1.95 mm). The 3 dB dimensions of the focused ultrasound (FUS) intensity focal volume increased on average by 39% (low: 4%, high: 122%). The 6 dB pressure focal volume increased by an average of 130 ± 75%. In general, the main effects of the skulls were power reduction, field dispersion and slight shift of focal peak location." @default.
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- W2016156790 date "2012-01-01" @default.
- W2016156790 modified "2023-09-23" @default.
- W2016156790 title "Transcranial measurements of the acoustic field produced by a low frequency focused ultrasound system" @default.
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- W2016156790 doi "https://doi.org/10.1063/1.4769954" @default.
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