FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016161775> ?p ?o ?g. }

• W2016161775 endingPage "iv90" @default.
• W2016161775 startingPage "iv86" @default.
• W2016161775 abstract "Dendritic cells (DCs) are often referred to as the body’s sentinels, constantly guarding against pathogens.1–3 In this role they are the antigen presenting cell that primes naive T cells in vivo.4 DCs also help maintain tolerance to “self” substances through multiple mechanisms that include T cell deletion and anergy as well as the generation of regulatory T cells.5–7 This dual role in regulating both immune responses and immune tolerance suggests that DCs are likely to have a role in autoimmune diseases such as lupus. The possibilities include presentation of “self” antigens as immunogens, a failure to delete autoreactive T cells, overproduction of inflammatory cytokines, and inadequate induction of regulatory T cells. As noted below, insights into these pathogenetic mechanisms in lupus are beginning to emerge. It is also clear that at least some of these activities of DCs can be manipulated through pharmacological agents.8,9It has been thought for a long time that regulatory T cells are related to the pathogenesis of lupus.10,11 Now, at the forefront of this consideration is the possibility that DCs play a critical role in balancing the array of autoreactive T cells with a corresponding set of regulatory T cells.12 It is clear that immature DCs induce deletional tolerance of autoreactive T cells in the periphery.13–15 However, the original concept that immature DCs are responsible for tolerance and mature DCs induce immune responses has given way to a more complex scenario in which DCs in different states of maturation are able to induce CD4+CD25+ regulatory T cells.16,17 In this paper, my aim is to consider the possibility that the maturation of DCs might be manipulated in such a way as to either enhance regulatory T cell generation or diminish priming of …" @default.
• W2016161775 created "2016-06-24" @default.
• W2016161775 creator A5089847238 @default.
• W2016161775 date "2005-11-01" @default.
• W2016161775 modified "2023-09-27" @default.
• W2016161775 title "Dendritic cells: potential triggers of autoimmunity and targets for therapy" @default.
• W2016161775 cites W1494759368 @default.
• W2016161775 cites W1510116615 @default.
• W2016161775 cites W152268165 @default.
• W2016161775 cites W1552925034 @default.
• W2016161775 cites W1577990808 @default.
• W2016161775 cites W1602287756 @default.
• W2016161775 cites W1713856372 @default.
• W2016161775 cites W1911894412 @default.
• W2016161775 cites W1918895486 @default.
• W2016161775 cites W1935519700 @default.
• W2016161775 cites W1955379330 @default.
• W2016161775 cites W1967113804 @default.
• W2016161775 cites W1968959595 @default.
• W2016161775 cites W1973431560 @default.
• W2016161775 cites W1975825759 @default.
• W2016161775 cites W1976521369 @default.
• W2016161775 cites W1977020088 @default.
• W2016161775 cites W1977609189 @default.
• W2016161775 cites W1985702891 @default.
• W2016161775 cites W1988262854 @default.
• W2016161775 cites W1997708871 @default.
• W2016161775 cites W2006083207 @default.
• W2016161775 cites W2006772331 @default.
• W2016161775 cites W2007751085 @default.
• W2016161775 cites W2009449806 @default.
• W2016161775 cites W2010724251 @default.
• W2016161775 cites W2014018213 @default.
• W2016161775 cites W2015697566 @default.
• W2016161775 cites W2017231245 @default.
• W2016161775 cites W2018790294 @default.
• W2016161775 cites W2020220487 @default.
• W2016161775 cites W2022952275 @default.
• W2016161775 cites W2024351056 @default.
• W2016161775 cites W2025739341 @default.
• W2016161775 cites W2031536528 @default.
• W2016161775 cites W2033874457 @default.
• W2016161775 cites W2041361352 @default.
• W2016161775 cites W2045109595 @default.
• W2016161775 cites W2048143404 @default.
• W2016161775 cites W2051907403 @default.
• W2016161775 cites W2053583666 @default.
• W2016161775 cites W2062512887 @default.
• W2016161775 cites W2065661920 @default.
• W2016161775 cites W2074292775 @default.
• W2016161775 cites W2078781814 @default.
• W2016161775 cites W2086438038 @default.
• W2016161775 cites W2090469992 @default.
• W2016161775 cites W2092492601 @default.
• W2016161775 cites W2099149994 @default.
• W2016161775 cites W2104904748 @default.
• W2016161775 cites W2105772115 @default.
• W2016161775 cites W2116372484 @default.
• W2016161775 cites W2116763454 @default.
• W2016161775 cites W2118437105 @default.
• W2016161775 cites W2118463883 @default.
• W2016161775 cites W2131761283 @default.
• W2016161775 cites W2132929600 @default.
• W2016161775 cites W2136394997 @default.
• W2016161775 cites W2139507768 @default.
• W2016161775 cites W2146577280 @default.
• W2016161775 cites W2148647317 @default.
• W2016161775 cites W2153288972 @default.
• W2016161775 cites W2154320943 @default.
• W2016161775 cites W2154463442 @default.
• W2016161775 cites W2161354474 @default.
• W2016161775 cites W2161503027 @default.
• W2016161775 cites W2163435594 @default.
• W2016161775 cites W2165575918 @default.
• W2016161775 cites W2167414668 @default.
• W2016161775 cites W2168888135 @default.
• W2016161775 cites W2171722021 @default.
• W2016161775 cites W2395767945 @default.
• W2016161775 cites W2404437346 @default.
• W2016161775 cites W3008175734 @default.
• W2016161775 cites W35413080 @default.
• W2016161775 doi "https://doi.org/10.1136/ard.2005.044560" @default.
• W2016161775 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1766899" @default.
• W2016161775 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16239396" @default.
• W2016161775 hasPublicationYear "2005" @default.
• W2016161775 type Work @default.
• W2016161775 sameAs 2016161775 @default.
• W2016161775 citedByCount "31" @default.
• W2016161775 countsByYear W20161617752012 @default.
• W2016161775 countsByYear W20161617752013 @default.
• W2016161775 countsByYear W20161617752014 @default.
• W2016161775 countsByYear W20161617752016 @default.
• W2016161775 countsByYear W20161617752017 @default.
• W2016161775 countsByYear W20161617752019 @default.
• W2016161775 countsByYear W20161617752022 @default.
• W2016161775 crossrefType "journal-article" @default.
• W2016161775 hasAuthorship W2016161775A5089847238 @default.
• W2016161775 hasBestOaLocation W20161617751 @default.

• next