Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016163945> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2016163945 endingPage "315" @default.
- W2016163945 startingPage "310" @default.
- W2016163945 abstract "<h2>Abstract</h2> Postmenopausal women in the Western world are highly burdened by osteoporotic fractures. The aim of this study is to investigate risk factors at baseline for fracture in 6416 postmenopausal women during long-term follow-up. At baseline, all women completed a questionnaire regarding background factors, diseases, current use of medications and reproductive and contraceptive history, a physical examination and laboratory analyses. Fracture occurrence after inclusion in the study was recorded with the help of official registries. All significant variables in univariate logistic regression with a decreased or increased risk for fracture were analysed in a multivariate logistic regression. Increased fracture risk was observed in women currently using proton pump inhibitors (PPI), odds ratio (OR) 2.53 (95% confidence interval (CI)) 1.28–4.99, and women having had a fracture after the age of 40, but before inclusion in the study, OR 1.70 (95% CI 1.24–2.32). A protective effect against fractures was observed in women with a positive family history of diabetes OR 0.66 (95% CI 0.44–0.98). A significant interaction was observed between fracture risk, use of PPI and HT status (<i>p</i>=0.014) and women with HT had an increased fracture risk with use of PPI (OR 3.37 (95% CI 1.96–5.80)) compared to women without HT (OR 1.13 (95% CI 0.57–2.24)). In conclusion, usage of PPIs was associated with a doubled risk for fracture in postmenopausal women. Women with previous fractures using PPI should be considered for prophylactic treatment reducing fracture risk." @default.
- W2016163945 created "2016-06-24" @default.
- W2016163945 creator A5020047304 @default.
- W2016163945 creator A5042623113 @default.
- W2016163945 creator A5054579436 @default.
- W2016163945 creator A5087556944 @default.
- W2016163945 date "2014-08-01" @default.
- W2016163945 modified "2023-09-25" @default.
- W2016163945 title "Use of proton pump inhibitors (PPI) and history of earlier fracture are independent risk factors for fracture in postmenopausal women. The WHILA study" @default.
- W2016163945 cites W1972328688 @default.
- W2016163945 cites W1976384386 @default.
- W2016163945 cites W1982503478 @default.
- W2016163945 cites W1983541513 @default.
- W2016163945 cites W1988521247 @default.
- W2016163945 cites W1991261783 @default.
- W2016163945 cites W2020732194 @default.
- W2016163945 cites W2030092052 @default.
- W2016163945 cites W2034934192 @default.
- W2016163945 cites W2049041037 @default.
- W2016163945 cites W2050587934 @default.
- W2016163945 cites W2067061442 @default.
- W2016163945 cites W2076075059 @default.
- W2016163945 cites W2085777428 @default.
- W2016163945 cites W2123564870 @default.
- W2016163945 cites W2136598250 @default.
- W2016163945 cites W2142913110 @default.
- W2016163945 cites W2254476945 @default.
- W2016163945 cites W4240851819 @default.
- W2016163945 cites W989545575 @default.
- W2016163945 doi "https://doi.org/10.1016/j.maturitas.2014.05.019" @default.
- W2016163945 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24958166" @default.
- W2016163945 hasPublicationYear "2014" @default.
- W2016163945 type Work @default.
- W2016163945 sameAs 2016163945 @default.
- W2016163945 citedByCount "42" @default.
- W2016163945 countsByYear W20161639452014 @default.
- W2016163945 countsByYear W20161639452015 @default.
- W2016163945 countsByYear W20161639452016 @default.
- W2016163945 countsByYear W20161639452017 @default.
- W2016163945 countsByYear W20161639452018 @default.
- W2016163945 countsByYear W20161639452019 @default.
- W2016163945 countsByYear W20161639452020 @default.
- W2016163945 countsByYear W20161639452021 @default.
- W2016163945 countsByYear W20161639452022 @default.
- W2016163945 countsByYear W20161639452023 @default.
- W2016163945 crossrefType "journal-article" @default.
- W2016163945 hasAuthorship W2016163945A5020047304 @default.
- W2016163945 hasAuthorship W2016163945A5042623113 @default.
- W2016163945 hasAuthorship W2016163945A5054579436 @default.
- W2016163945 hasAuthorship W2016163945A5087556944 @default.
- W2016163945 hasConcept C126322002 @default.
- W2016163945 hasConcept C131872663 @default.
- W2016163945 hasConcept C144301174 @default.
- W2016163945 hasConcept C151956035 @default.
- W2016163945 hasConcept C156957248 @default.
- W2016163945 hasConcept C2781025758 @default.
- W2016163945 hasConcept C3018603563 @default.
- W2016163945 hasConcept C38180746 @default.
- W2016163945 hasConcept C44249647 @default.
- W2016163945 hasConcept C50440223 @default.
- W2016163945 hasConcept C71924100 @default.
- W2016163945 hasConceptScore W2016163945C126322002 @default.
- W2016163945 hasConceptScore W2016163945C131872663 @default.
- W2016163945 hasConceptScore W2016163945C144301174 @default.
- W2016163945 hasConceptScore W2016163945C151956035 @default.
- W2016163945 hasConceptScore W2016163945C156957248 @default.
- W2016163945 hasConceptScore W2016163945C2781025758 @default.
- W2016163945 hasConceptScore W2016163945C3018603563 @default.
- W2016163945 hasConceptScore W2016163945C38180746 @default.
- W2016163945 hasConceptScore W2016163945C44249647 @default.
- W2016163945 hasConceptScore W2016163945C50440223 @default.
- W2016163945 hasConceptScore W2016163945C71924100 @default.
- W2016163945 hasIssue "4" @default.
- W2016163945 hasLocation W20161639451 @default.
- W2016163945 hasLocation W20161639452 @default.
- W2016163945 hasOpenAccess W2016163945 @default.
- W2016163945 hasPrimaryLocation W20161639451 @default.
- W2016163945 hasRelatedWork W2069785877 @default.
- W2016163945 hasRelatedWork W2119000026 @default.
- W2016163945 hasRelatedWork W2133897615 @default.
- W2016163945 hasRelatedWork W2171251595 @default.
- W2016163945 hasRelatedWork W2520493033 @default.
- W2016163945 hasRelatedWork W2767445481 @default.
- W2016163945 hasRelatedWork W2972751454 @default.
- W2016163945 hasRelatedWork W3021932827 @default.
- W2016163945 hasRelatedWork W3031421533 @default.
- W2016163945 hasRelatedWork W4293569637 @default.
- W2016163945 hasVolume "78" @default.
- W2016163945 isParatext "false" @default.
- W2016163945 isRetracted "false" @default.
- W2016163945 magId "2016163945" @default.
- W2016163945 workType "article" @default.