FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016165381> ?p ?o ?g. }

• W2016165381 endingPage "222" @default.
• W2016165381 startingPage "216" @default.
• W2016165381 abstract "Endocannabinoids (eCBs) are endogenous lipids that bind principally type-1 and type-2 cannabinoid (CB1 and CB2) receptors. N-Arachidonoylethanolamine (AEA, anandamide) and 2-arachidonoylglycerol (2-AG) are the best characterized eCBs that are released from membrane phospholipid precursors through multiple biosynthetic pathways. Together with their receptors and metabolic enzymes, eCBs form the so-called “eCB system”. The later has been involved in a wide variety of actions, including modulation of basal ganglia function. Consistently, both eCB levels and CB1 receptor expression are high in several basal ganglia regions, and more specifically in the striatum and in its target projection areas. In these regions, the eCB system establishes a close functional interaction with dopaminergic neurotransmission, supporting a relevant role for eCBs in the control of voluntary movements. Accordingly, compelling experimental and clinical evidence suggests that a profound rearrangement of the eCB system in the basal ganglia follows dopamine depletion, as it occurs in Parkinson's disease (PD). In this article, we provide a brief survey of the evidence that the eCB system changes in both animal models of, and patients suffering from, PD. A striking convergence of findings is observed between both rodent and primate models and PD patients, indicating that the eCB system undergoes dynamic, adaptive changes, aimed at restoring an apparent homeostasis within the basal ganglia network. © 2010 Movement Disorder Society" @default.
• W2016165381 created "2016-06-24" @default.
• W2016165381 creator A5022210828 @default.
• W2016165381 creator A5054609820 @default.
• W2016165381 creator A5063063427 @default.
• W2016165381 creator A5079527374 @default.
• W2016165381 creator A5084489352 @default.
• W2016165381 creator A5087471580 @default.
• W2016165381 creator A5087976071 @default.
• W2016165381 date "2010-12-13" @default.
• W2016165381 modified "2023-09-29" @default.
• W2016165381 title "Homeostatic changes of the endocannabinoid system in Parkinson's disease" @default.
• W2016165381 cites W1507839329 @default.
• W2016165381 cites W1513230591 @default.
• W2016165381 cites W1568165441 @default.
• W2016165381 cites W1971797700 @default.
• W2016165381 cites W1982827121 @default.
• W2016165381 cites W1992854762 @default.
• W2016165381 cites W1993109240 @default.
• W2016165381 cites W1997563619 @default.
• W2016165381 cites W1998482526 @default.
• W2016165381 cites W1998937162 @default.
• W2016165381 cites W2003314029 @default.
• W2016165381 cites W2011142394 @default.
• W2016165381 cites W2020978550 @default.
• W2016165381 cites W2025077832 @default.
• W2016165381 cites W2025422724 @default.
• W2016165381 cites W2026506478 @default.
• W2016165381 cites W2027336116 @default.
• W2016165381 cites W2031897813 @default.
• W2016165381 cites W2035926968 @default.
• W2016165381 cites W2038487696 @default.
• W2016165381 cites W2041366408 @default.
• W2016165381 cites W2042587343 @default.
• W2016165381 cites W2044361156 @default.
• W2016165381 cites W2060277249 @default.
• W2016165381 cites W2073116630 @default.
• W2016165381 cites W2077225716 @default.
• W2016165381 cites W2077648124 @default.
• W2016165381 cites W2086614467 @default.
• W2016165381 cites W2096003899 @default.
• W2016165381 cites W2098783607 @default.
• W2016165381 cites W2099570835 @default.
• W2016165381 cites W2104513822 @default.
• W2016165381 cites W2108710772 @default.
• W2016165381 cites W2116754069 @default.
• W2016165381 cites W2124429694 @default.
• W2016165381 cites W2125004892 @default.
• W2016165381 cites W2150496269 @default.
• W2016165381 cites W2151413914 @default.
• W2016165381 cites W2152316935 @default.
• W2016165381 cites W2158248179 @default.
• W2016165381 cites W2161344628 @default.
• W2016165381 cites W2165151662 @default.
• W2016165381 cites W2171260594 @default.
• W2016165381 cites W2171494808 @default.
• W2016165381 cites W2740143460 @default.
• W2016165381 cites W315237111 @default.
• W2016165381 cites W4247729308 @default.
• W2016165381 doi "https://doi.org/10.1002/mds.23457" @default.
• W2016165381 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21412829" @default.
• W2016165381 hasPublicationYear "2010" @default.
• W2016165381 type Work @default.
• W2016165381 sameAs 2016165381 @default.
• W2016165381 citedByCount "45" @default.
• W2016165381 countsByYear W20161653812012 @default.
• W2016165381 countsByYear W20161653812013 @default.
• W2016165381 countsByYear W20161653812014 @default.
• W2016165381 countsByYear W20161653812015 @default.
• W2016165381 countsByYear W20161653812016 @default.
• W2016165381 countsByYear W20161653812017 @default.
• W2016165381 countsByYear W20161653812018 @default.
• W2016165381 countsByYear W20161653812019 @default.
• W2016165381 countsByYear W20161653812020 @default.
• W2016165381 countsByYear W20161653812021 @default.
• W2016165381 countsByYear W20161653812022 @default.
• W2016165381 countsByYear W20161653812023 @default.
• W2016165381 crossrefType "journal-article" @default.
• W2016165381 hasAuthorship W2016165381A5022210828 @default.
• W2016165381 hasAuthorship W2016165381A5054609820 @default.
• W2016165381 hasAuthorship W2016165381A5063063427 @default.
• W2016165381 hasAuthorship W2016165381A5079527374 @default.
• W2016165381 hasAuthorship W2016165381A5084489352 @default.
• W2016165381 hasAuthorship W2016165381A5087471580 @default.
• W2016165381 hasAuthorship W2016165381A5087976071 @default.
• W2016165381 hasConcept C126322002 @default.
• W2016165381 hasConcept C137183658 @default.
• W2016165381 hasConcept C148001335 @default.
• W2016165381 hasConcept C169760540 @default.
• W2016165381 hasConcept C170493617 @default.
• W2016165381 hasConcept C2778187257 @default.
• W2016165381 hasConcept C2778938600 @default.
• W2016165381 hasConcept C2779134260 @default.
• W2016165381 hasConcept C2779734285 @default.
• W2016165381 hasConcept C2780062018 @default.
• W2016165381 hasConcept C2780871563 @default.
• W2016165381 hasConcept C46721173 @default.
• W2016165381 hasConcept C513476851 @default.

• next