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- W2016169787 abstract "Percutaneous coronary intervention (PCI) with BMS has been reported to be associated with poor outcome in heart transplant recipient. We aimed to assess the outcome of successful PCI with bare-metal stents (BMS) or drug-eluting stents (DES) in heart transplant recipients. Ninety-four consecutive heart transplant recipients with successful PCI of de novo lesions with BMS (n=53) or DES (n=60) were prospectively followed-up for 41.8±31.5 months after the PCI. The lesion-based analysis within 12 months after PCI showed a marked reduction of target lesion revascularization (TLR) and restenosis rates by the use of DES (6.9% versus 26.4%, p=0.005 and 7.1% versus 32.1%, p=0.001 respectively). The patient-based multivariable analysis identified transplantation to PCI time (HR 1.1 per month), absence of antihypertensive therapy (HR 4.53) and left ventricular ejection fraction (HR 0.95 per percent) but not stent type as independent correlates of death. BMS (HR 3.79) and tacrolimus use (HR 8.32) were independent correlates of TLR. Compared to BMS, DES are associated with a marked reduction in rates of restenosis and TLR in heart transplant recipients and may be recommended despite the absence of a relationship between the stent type and survival. Early treatment of allograft vasculopathy, extensive antihypertensive therapy and left ventricular function preservation, appear as major goals of treatment to improve long-term survival in such patients." @default.
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- W2016169787 date "2010-01-01" @default.
- W2016169787 modified "2023-09-23" @default.
- W2016169787 title "326 Long-term Outcome after Bare-Metal or Drug-Eluting Stenting for Allograft Coronary Artery Disease" @default.
- W2016169787 doi "https://doi.org/10.1016/s1878-6480(10)70328-1" @default.
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