FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016174313> ?p ?o ?g. }

• W2016174313 endingPage "86" @default.
• W2016174313 startingPage "80" @default.
• W2016174313 abstract "Diet may induce colon carcinogenesis through oxidative or alkylating DNA damage. However, diet may also contain anticarcinogenic compounds that contribute to cancer prevention. DNA damage prevention and/or induction of repair are two important mechanisms involved in cancer chemoprevention by dietary compounds. Hypericum sps. are widely used in traditional medicine to prepare infusions due to their beneficial digestive and neurologic effects. In this study, we investigated the potential of water extracts from three Hypericum sps. and some of their main phenolic compounds to prevent and repair oxidative and alkylating DNA damage in colon cells. The results showed that water extracts of Hypericum perforatum, Hypericum androsaemum, Hypericum undulatum, quercetin and rutin have protective effect against oxidative DNA damage in HT29 cells. Protective effect was also observed against alkylating DNA damage induced by methyl-methanesulfonate, except for H. androsaemum. With regard to alkylating damage repair H. perforatum, H. androsaemum and chlorogenic acid increased repair of alkylating DNA damage by base excision repair pathway. No effect was observed on nucleotide excision repair pathway. Antigenotoxic effects of Hypericum sps. may contribute to colon cancer prevention and the high amount of phenolic compounds present in Hypericum sps. play an important role in DNA protective effects." @default.
• W2016174313 created "2016-06-24" @default.
• W2016174313 creator A5020843117 @default.
• W2016174313 creator A5056268235 @default.
• W2016174313 creator A5056729297 @default.
• W2016174313 creator A5075919237 @default.
• W2016174313 date "2013-01-01" @default.
• W2016174313 modified "2023-09-23" @default.
• W2016174313 title "Water extracts of tree Hypericum sps. protect DNA from oxidative and alkylating damage and enhance DNA repair in colon cells" @default.
• W2016174313 cites W1973675016 @default.
• W2016174313 cites W1974137987 @default.
• W2016174313 cites W1991690086 @default.
• W2016174313 cites W1996501478 @default.
• W2016174313 cites W2005206848 @default.
• W2016174313 cites W2010276640 @default.
• W2016174313 cites W2014411704 @default.
• W2016174313 cites W2015450783 @default.
• W2016174313 cites W2017626786 @default.
• W2016174313 cites W2019432352 @default.
• W2016174313 cites W2021133687 @default.
• W2016174313 cites W2025546384 @default.
• W2016174313 cites W2025999634 @default.
• W2016174313 cites W2034720034 @default.
• W2016174313 cites W2036386212 @default.
• W2016174313 cites W2056512550 @default.
• W2016174313 cites W2059153272 @default.
• W2016174313 cites W2059221492 @default.
• W2016174313 cites W2062464534 @default.
• W2016174313 cites W2065606021 @default.
• W2016174313 cites W2069936677 @default.
• W2016174313 cites W2071964246 @default.
• W2016174313 cites W2080032638 @default.
• W2016174313 cites W2089350722 @default.
• W2016174313 cites W2112013559 @default.
• W2016174313 cites W2122673427 @default.
• W2016174313 cites W2130092087 @default.
• W2016174313 cites W2134891788 @default.
• W2016174313 cites W2135729013 @default.
• W2016174313 cites W2147696493 @default.
• W2016174313 cites W2148083325 @default.
• W2016174313 cites W2152276102 @default.
• W2016174313 cites W4210989642 @default.
• W2016174313 doi "https://doi.org/10.1016/j.fct.2012.09.014" @default.
• W2016174313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23000446" @default.
• W2016174313 hasPublicationYear "2013" @default.
• W2016174313 type Work @default.
• W2016174313 sameAs 2016174313 @default.
• W2016174313 citedByCount "17" @default.
• W2016174313 countsByYear W20161743132013 @default.
• W2016174313 countsByYear W20161743132016 @default.
• W2016174313 countsByYear W20161743132017 @default.
• W2016174313 countsByYear W20161743132019 @default.
• W2016174313 countsByYear W20161743132020 @default.
• W2016174313 countsByYear W20161743132021 @default.
• W2016174313 countsByYear W20161743132022 @default.
• W2016174313 crossrefType "journal-article" @default.
• W2016174313 hasAuthorship W2016174313A5020843117 @default.
• W2016174313 hasAuthorship W2016174313A5056268235 @default.
• W2016174313 hasAuthorship W2016174313A5056729297 @default.
• W2016174313 hasAuthorship W2016174313A5075919237 @default.
• W2016174313 hasConcept C104317684 @default.
• W2016174313 hasConcept C134935766 @default.
• W2016174313 hasConcept C143425029 @default.
• W2016174313 hasConcept C185592680 @default.
• W2016174313 hasConcept C2776151105 @default.
• W2016174313 hasConcept C2776651039 @default.
• W2016174313 hasConcept C2778215561 @default.
• W2016174313 hasConcept C552990157 @default.
• W2016174313 hasConcept C55493867 @default.
• W2016174313 hasConcept C555283112 @default.
• W2016174313 hasConcept C59822182 @default.
• W2016174313 hasConcept C86803240 @default.
• W2016174313 hasConcept C98274493 @default.
• W2016174313 hasConceptScore W2016174313C104317684 @default.
• W2016174313 hasConceptScore W2016174313C134935766 @default.
• W2016174313 hasConceptScore W2016174313C143425029 @default.
• W2016174313 hasConceptScore W2016174313C185592680 @default.
• W2016174313 hasConceptScore W2016174313C2776151105 @default.
• W2016174313 hasConceptScore W2016174313C2776651039 @default.
• W2016174313 hasConceptScore W2016174313C2778215561 @default.
• W2016174313 hasConceptScore W2016174313C552990157 @default.
• W2016174313 hasConceptScore W2016174313C55493867 @default.
• W2016174313 hasConceptScore W2016174313C555283112 @default.
• W2016174313 hasConceptScore W2016174313C59822182 @default.
• W2016174313 hasConceptScore W2016174313C86803240 @default.
• W2016174313 hasConceptScore W2016174313C98274493 @default.
• W2016174313 hasLocation W20161743131 @default.
• W2016174313 hasLocation W20161743132 @default.
• W2016174313 hasOpenAccess W2016174313 @default.
• W2016174313 hasPrimaryLocation W20161743131 @default.
• W2016174313 hasRelatedWork W143687651 @default.
• W2016174313 hasRelatedWork W2000904856 @default.
• W2016174313 hasRelatedWork W2002637963 @default.
• W2016174313 hasRelatedWork W2015612551 @default.
• W2016174313 hasRelatedWork W2016174313 @default.
• W2016174313 hasRelatedWork W2062551448 @default.
• W2016174313 hasRelatedWork W2320615665 @default.
• W2016174313 hasRelatedWork W2328839710 @default.

• next