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• W2016176507 abstract "Free radical-mediated oxidative stress has been implicated in the pathogenesis of numerous chronic diseases. Vitamin E is known to play an important role in the free-radical quenching process. However, clinical trials with vitamin E have yielded contrasting results in the prevention of several diseases related to oxidative stress. This study was undertaken to investigate the antioxidative and humoral immunologic effects of vitamin E supplementation in three different age groups: young (mean age 32.7±5.7 y), middle-aged (mean age 47.0±5.0 y) and elderly (67.6±4.7 y) women. Volunteer subjects were given a supplement of 400 IU dl-α-tocopherol acetate for 6 wk. Thiobarbituric acid reacting substances (TBARS) in the plasma significantly decreased with vitamin E supplementation. In addition, the radical scavenger activities (RSA) of red blood cells significantly increased with vitamin E supplementation in all age groups. However, humoral immune response modulation was not observed following vitamin E supplementation. Even though there is no clear indication that vitamin E supplementation is necessary to improve the humoral immune functions, vitamin E supplementation may be beneficial to all adult age groups as a preventive measure for complications related to oxidative damage." @default.
• W2016176507 created "2016-06-24" @default.
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• W2016176507 date "2003-01-01" @default.
• W2016176507 modified "2023-09-27" @default.
• W2016176507 title "Effect of Vitamin E Supplementation on Antioxidant Defense Systems and Humoral Immune Responses in Young, Middle-Aged and Elderly Korean Women" @default.
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• W2016176507 doi "https://doi.org/10.3177/jnsv.49.94" @default.
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