FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016194182> ?p ?o ?g. }

• W2016194182 endingPage "408" @default.
• W2016194182 startingPage "405" @default.
• W2016194182 abstract "There exist studies indicating that bipolar disorder (BD) associates with changes in brain blood flow. Human brain with its high demand to oxygen constitutes 2% of the total body weight, while it receives 20% of cardiac output. α and β globin chains of hemoglobin were recently found in neural tissues, yet no study has questioned blood hemoglobins in BD. A total of 120 euthymic BD patients (40 males and 80 females) were analyzed via high performance liquid chromatography (HPLC) to measure minor hemoglobin levels, which were statistically compared with disease characteristics. Minor hemoglobins HbA2 and HbF associated positively with episode density as a measure of disease severity in BD. An increased level of HbA2 meant significantly less postpartum episodes in child bearing women. HbF levels were higher in patients with a positive family history of any psychotic disorder. Sum of HbA2 and HbF correlated with episode density with a stronger significance (p<0.001) supporting intermittent hypoxia hypothesis in BD. The study was conducted only on euthymic patients to avoid likely bigger exogenous effects such as electro-convulsive therapy and diverse drug regimes, yet larger comparative studies are needed to support our current findings. Higher HbA2 and HbF in more severe bipolar disorder may be compensations against intermittent hypoxias in BD. HbA2 increases following myocardial angina and in mountain dwellers, which may indicate protective roles in extreme conditions. HbF increase may act more as a maladaptation or emerge via haplotypal associations of BD genes and gamma-globin locus at 11p15.5." @default.
• W2016194182 created "2016-06-24" @default.
• W2016194182 creator A5009962431 @default.
• W2016194182 creator A5036606532 @default.
• W2016194182 creator A5043535644 @default.
• W2016194182 creator A5051785987 @default.
• W2016194182 creator A5056395597 @default.
• W2016194182 creator A5086948625 @default.
• W2016194182 date "2013-10-01" @default.
• W2016194182 modified "2023-09-30" @default.
• W2016194182 title "Minor hemoglobins HbA2 and HbF associate with disease severity in bipolar disorder with a likely protective role of HbA2 against post-partum episodes" @default.
• W2016194182 cites W1509196591 @default.
• W2016194182 cites W1513387180 @default.
• W2016194182 cites W1960924050 @default.
• W2016194182 cites W1970019957 @default.
• W2016194182 cites W1974077867 @default.
• W2016194182 cites W1978480599 @default.
• W2016194182 cites W1994991085 @default.
• W2016194182 cites W1996225549 @default.
• W2016194182 cites W1998711749 @default.
• W2016194182 cites W2003115630 @default.
• W2016194182 cites W2007786273 @default.
• W2016194182 cites W2019268044 @default.
• W2016194182 cites W2027254934 @default.
• W2016194182 cites W2030162700 @default.
• W2016194182 cites W2040673110 @default.
• W2016194182 cites W2042285371 @default.
• W2016194182 cites W2048490730 @default.
• W2016194182 cites W2050254094 @default.
• W2016194182 cites W2050751712 @default.
• W2016194182 cites W2052355822 @default.
• W2016194182 cites W2069562922 @default.
• W2016194182 cites W2081802461 @default.
• W2016194182 cites W2089889230 @default.
• W2016194182 cites W2090408420 @default.
• W2016194182 cites W2092574926 @default.
• W2016194182 cites W2099680004 @default.
• W2016194182 cites W2119524641 @default.
• W2016194182 cites W2124748968 @default.
• W2016194182 cites W21555123 @default.
• W2016194182 cites W2293741471 @default.
• W2016194182 cites W2408833185 @default.
• W2016194182 doi "https://doi.org/10.1016/j.jad.2013.06.042" @default.
• W2016194182 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23856286" @default.
• W2016194182 hasPublicationYear "2013" @default.
• W2016194182 type Work @default.
• W2016194182 sameAs 2016194182 @default.
• W2016194182 citedByCount "11" @default.
• W2016194182 countsByYear W20161941822014 @default.
• W2016194182 countsByYear W20161941822016 @default.
• W2016194182 countsByYear W20161941822017 @default.
• W2016194182 countsByYear W20161941822018 @default.
• W2016194182 countsByYear W20161941822019 @default.
• W2016194182 countsByYear W20161941822020 @default.
• W2016194182 countsByYear W20161941822022 @default.
• W2016194182 countsByYear W20161941822023 @default.
• W2016194182 crossrefType "journal-article" @default.
• W2016194182 hasAuthorship W2016194182A5009962431 @default.
• W2016194182 hasAuthorship W2016194182A5036606532 @default.
• W2016194182 hasAuthorship W2016194182A5043535644 @default.
• W2016194182 hasAuthorship W2016194182A5051785987 @default.
• W2016194182 hasAuthorship W2016194182A5056395597 @default.
• W2016194182 hasAuthorship W2016194182A5086948625 @default.
• W2016194182 hasConcept C118552586 @default.
• W2016194182 hasConcept C126322002 @default.
• W2016194182 hasConcept C15744967 @default.
• W2016194182 hasConcept C157767197 @default.
• W2016194182 hasConcept C169900460 @default.
• W2016194182 hasConcept C172680121 @default.
• W2016194182 hasConcept C182025440 @default.
• W2016194182 hasConcept C2776174506 @default.
• W2016194182 hasConcept C2776317666 @default.
• W2016194182 hasConcept C2777216359 @default.
• W2016194182 hasConcept C2778917026 @default.
• W2016194182 hasConcept C2779134260 @default.
• W2016194182 hasConcept C2779234561 @default.
• W2016194182 hasConcept C42407357 @default.
• W2016194182 hasConcept C54355233 @default.
• W2016194182 hasConcept C71924100 @default.
• W2016194182 hasConcept C86803240 @default.
• W2016194182 hasConceptScore W2016194182C118552586 @default.
• W2016194182 hasConceptScore W2016194182C126322002 @default.
• W2016194182 hasConceptScore W2016194182C15744967 @default.
• W2016194182 hasConceptScore W2016194182C157767197 @default.
• W2016194182 hasConceptScore W2016194182C169900460 @default.
• W2016194182 hasConceptScore W2016194182C172680121 @default.
• W2016194182 hasConceptScore W2016194182C182025440 @default.
• W2016194182 hasConceptScore W2016194182C2776174506 @default.
• W2016194182 hasConceptScore W2016194182C2776317666 @default.
• W2016194182 hasConceptScore W2016194182C2777216359 @default.
• W2016194182 hasConceptScore W2016194182C2778917026 @default.
• W2016194182 hasConceptScore W2016194182C2779134260 @default.
• W2016194182 hasConceptScore W2016194182C2779234561 @default.
• W2016194182 hasConceptScore W2016194182C42407357 @default.
• W2016194182 hasConceptScore W2016194182C54355233 @default.
• W2016194182 hasConceptScore W2016194182C71924100 @default.
• W2016194182 hasConceptScore W2016194182C86803240 @default.
• W2016194182 hasIssue "1" @default.

• next