Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016198719> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2016198719 endingPage "357" @default.
- W2016198719 startingPage "350" @default.
- W2016198719 abstract "Using surface fluorescence and reflectance measurements from the exposed cerebral cortex, several potential-sensitive molecular probes, primarily oxonol V, have been evaluated as indicators of electrical activity changes developing during seizure activity in the mongolian gerbil. Intraventricular injection of bicuculline, picrotoxin, or KCl produced characteristic cyclic molecular probe fluorescence intensity descreases that could be abolished by the uncoupler CCCP or the mitochondrial electron transport inhibitor rotenone. Smaller fluorophore signals were observed when KCl was applied topically to the exposed cortex. In some cases, as the animals were recovering from anoxia induced by nitrogen inhalation, oscillations similar to those due to spreading depression were observed in both the oxonol V and pyridine nucleotide signals. In all experiments, the molecular probe signals closely followed those of the intrinsic pyridine nucleotides. The drug-induced oxonol V signal alterations have been provisionally interpreted as due to at least in part of the reduction of the mitochondrial membrane potential that accompanies a state 4 to state 3 transition. Measurements at the oxonol V fluorescence excitation wavelength indicated that only small changes in the reflectance signal occurred during seizure activity suggesting minimal blood volume change contributions to the extrinsic probe signal." @default.
- W2016198719 created "2016-06-24" @default.
- W2016198719 creator A5013036455 @default.
- W2016198719 creator A5081026696 @default.
- W2016198719 date "1987-04-01" @default.
- W2016198719 modified "2023-10-15" @default.
- W2016198719 title "Seizure activity and cortical spreading depression monitored by an extrinsic potential-sensitive molecular probe" @default.
- W2016198719 cites W1479976296 @default.
- W2016198719 cites W1497174676 @default.
- W2016198719 cites W1605717451 @default.
- W2016198719 cites W1608114920 @default.
- W2016198719 cites W1967660855 @default.
- W2016198719 cites W1980040556 @default.
- W2016198719 cites W1988278189 @default.
- W2016198719 cites W2005772083 @default.
- W2016198719 cites W2016951447 @default.
- W2016198719 cites W2033256212 @default.
- W2016198719 cites W2034219019 @default.
- W2016198719 cites W2057617446 @default.
- W2016198719 cites W2072227605 @default.
- W2016198719 cites W2077782033 @default.
- W2016198719 cites W2078736801 @default.
- W2016198719 cites W2100673847 @default.
- W2016198719 cites W2105979237 @default.
- W2016198719 cites W2145612182 @default.
- W2016198719 cites W2217637761 @default.
- W2016198719 cites W2295353816 @default.
- W2016198719 cites W2336435135 @default.
- W2016198719 cites W2596847243 @default.
- W2016198719 doi "https://doi.org/10.1016/0006-8993(87)90721-9" @default.
- W2016198719 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3580882" @default.
- W2016198719 hasPublicationYear "1987" @default.
- W2016198719 type Work @default.
- W2016198719 sameAs 2016198719 @default.
- W2016198719 citedByCount "5" @default.
- W2016198719 crossrefType "journal-article" @default.
- W2016198719 hasAuthorship W2016198719A5013036455 @default.
- W2016198719 hasAuthorship W2016198719A5081026696 @default.
- W2016198719 hasConcept C121332964 @default.
- W2016198719 hasConcept C122356138 @default.
- W2016198719 hasConcept C12554922 @default.
- W2016198719 hasConcept C126322002 @default.
- W2016198719 hasConcept C168258287 @default.
- W2016198719 hasConcept C169760540 @default.
- W2016198719 hasConcept C170493617 @default.
- W2016198719 hasConcept C181911157 @default.
- W2016198719 hasConcept C185592680 @default.
- W2016198719 hasConcept C2777348757 @default.
- W2016198719 hasConcept C2778541695 @default.
- W2016198719 hasConcept C2778617687 @default.
- W2016198719 hasConcept C2780763569 @default.
- W2016198719 hasConcept C55493867 @default.
- W2016198719 hasConcept C62520636 @default.
- W2016198719 hasConcept C71924100 @default.
- W2016198719 hasConcept C86803240 @default.
- W2016198719 hasConcept C91881484 @default.
- W2016198719 hasConceptScore W2016198719C121332964 @default.
- W2016198719 hasConceptScore W2016198719C122356138 @default.
- W2016198719 hasConceptScore W2016198719C12554922 @default.
- W2016198719 hasConceptScore W2016198719C126322002 @default.
- W2016198719 hasConceptScore W2016198719C168258287 @default.
- W2016198719 hasConceptScore W2016198719C169760540 @default.
- W2016198719 hasConceptScore W2016198719C170493617 @default.
- W2016198719 hasConceptScore W2016198719C181911157 @default.
- W2016198719 hasConceptScore W2016198719C185592680 @default.
- W2016198719 hasConceptScore W2016198719C2777348757 @default.
- W2016198719 hasConceptScore W2016198719C2778541695 @default.
- W2016198719 hasConceptScore W2016198719C2778617687 @default.
- W2016198719 hasConceptScore W2016198719C2780763569 @default.
- W2016198719 hasConceptScore W2016198719C55493867 @default.
- W2016198719 hasConceptScore W2016198719C62520636 @default.
- W2016198719 hasConceptScore W2016198719C71924100 @default.
- W2016198719 hasConceptScore W2016198719C86803240 @default.
- W2016198719 hasConceptScore W2016198719C91881484 @default.
- W2016198719 hasIssue "2" @default.
- W2016198719 hasLocation W20161987191 @default.
- W2016198719 hasLocation W20161987192 @default.
- W2016198719 hasOpenAccess W2016198719 @default.
- W2016198719 hasPrimaryLocation W20161987191 @default.
- W2016198719 hasRelatedWork W1942598677 @default.
- W2016198719 hasRelatedWork W1989921092 @default.
- W2016198719 hasRelatedWork W2005353190 @default.
- W2016198719 hasRelatedWork W2028210835 @default.
- W2016198719 hasRelatedWork W2036797720 @default.
- W2016198719 hasRelatedWork W2039987293 @default.
- W2016198719 hasRelatedWork W2087930239 @default.
- W2016198719 hasRelatedWork W2104532925 @default.
- W2016198719 hasRelatedWork W2330712598 @default.
- W2016198719 hasRelatedWork W71363804 @default.
- W2016198719 hasVolume "409" @default.
- W2016198719 isParatext "false" @default.
- W2016198719 isRetracted "false" @default.
- W2016198719 magId "2016198719" @default.
- W2016198719 workType "article" @default.