Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016203598> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2016203598 endingPage "360" @default.
- W2016203598 startingPage "354" @default.
- W2016203598 abstract "A genetically homogeneous population of Plasmodium falciparum prepared by a single erythrocyte micromanipulation technique was used to produce lines of P. falciparum resistant to mefloquine hydrochloride in vitro. Parasites were maintained in a culture medium containing gradually increased concentrations of mefloquine hydrochloride (CMP-mef) starting with 2 ng/ml. One of the mefloquine-resistant culture lines (W2-mef) was obtained after 96 weeks of continuous culture in CMP-mef, the last 4 weeks in medium containing 40 ng/ml of mefloquine hydrochloride. The W2-mef was four to six times more resistant to mefloquine than was the parent clone W2. Means of multiple determinations of 50% inhibitory concentrations (IC-50) of mefloquine hydrochloride against W2-mef and clone W2 were 20.39 +/- 5.08 ng/ml and 4.50 +/- 1.94 ng/ml, respectively." @default.
- W2016203598 created "2016-06-24" @default.
- W2016203598 creator A5024543549 @default.
- W2016203598 creator A5048592207 @default.
- W2016203598 creator A5049350014 @default.
- W2016203598 creator A5059125807 @default.
- W2016203598 creator A5077273005 @default.
- W2016203598 date "1988-12-01" @default.
- W2016203598 modified "2023-10-15" @default.
- W2016203598 title "Plasmodium falciparum: Induction of resistance to mefloquine in cloned strains by continuous drug exposure in vitro" @default.
- W2016203598 cites W1969503178 @default.
- W2016203598 cites W1974720373 @default.
- W2016203598 cites W1984709389 @default.
- W2016203598 cites W1984979458 @default.
- W2016203598 cites W1987276135 @default.
- W2016203598 cites W1994995194 @default.
- W2016203598 cites W2009943836 @default.
- W2016203598 cites W2042135186 @default.
- W2016203598 cites W2105668259 @default.
- W2016203598 cites W2258226205 @default.
- W2016203598 cites W2410011955 @default.
- W2016203598 cites W2474562609 @default.
- W2016203598 doi "https://doi.org/10.1016/0014-4894(88)90082-3" @default.
- W2016203598 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3056740" @default.
- W2016203598 hasPublicationYear "1988" @default.
- W2016203598 type Work @default.
- W2016203598 sameAs 2016203598 @default.
- W2016203598 citedByCount "134" @default.
- W2016203598 countsByYear W20162035982012 @default.
- W2016203598 countsByYear W20162035982013 @default.
- W2016203598 countsByYear W20162035982014 @default.
- W2016203598 countsByYear W20162035982015 @default.
- W2016203598 countsByYear W20162035982016 @default.
- W2016203598 countsByYear W20162035982017 @default.
- W2016203598 countsByYear W20162035982018 @default.
- W2016203598 countsByYear W20162035982019 @default.
- W2016203598 countsByYear W20162035982020 @default.
- W2016203598 countsByYear W20162035982021 @default.
- W2016203598 countsByYear W20162035982022 @default.
- W2016203598 countsByYear W20162035982023 @default.
- W2016203598 crossrefType "journal-article" @default.
- W2016203598 hasAuthorship W2016203598A5024543549 @default.
- W2016203598 hasAuthorship W2016203598A5048592207 @default.
- W2016203598 hasAuthorship W2016203598A5049350014 @default.
- W2016203598 hasAuthorship W2016203598A5059125807 @default.
- W2016203598 hasAuthorship W2016203598A5077273005 @default.
- W2016203598 hasConcept C104317684 @default.
- W2016203598 hasConcept C114851261 @default.
- W2016203598 hasConcept C159047783 @default.
- W2016203598 hasConcept C202751555 @default.
- W2016203598 hasConcept C203014093 @default.
- W2016203598 hasConcept C2777199930 @default.
- W2016203598 hasConcept C2778048844 @default.
- W2016203598 hasConcept C2778371730 @default.
- W2016203598 hasConcept C2908647359 @default.
- W2016203598 hasConcept C55493867 @default.
- W2016203598 hasConcept C71924100 @default.
- W2016203598 hasConcept C81089528 @default.
- W2016203598 hasConcept C86803240 @default.
- W2016203598 hasConcept C89423630 @default.
- W2016203598 hasConcept C98274493 @default.
- W2016203598 hasConcept C99454951 @default.
- W2016203598 hasConceptScore W2016203598C104317684 @default.
- W2016203598 hasConceptScore W2016203598C114851261 @default.
- W2016203598 hasConceptScore W2016203598C159047783 @default.
- W2016203598 hasConceptScore W2016203598C202751555 @default.
- W2016203598 hasConceptScore W2016203598C203014093 @default.
- W2016203598 hasConceptScore W2016203598C2777199930 @default.
- W2016203598 hasConceptScore W2016203598C2778048844 @default.
- W2016203598 hasConceptScore W2016203598C2778371730 @default.
- W2016203598 hasConceptScore W2016203598C2908647359 @default.
- W2016203598 hasConceptScore W2016203598C55493867 @default.
- W2016203598 hasConceptScore W2016203598C71924100 @default.
- W2016203598 hasConceptScore W2016203598C81089528 @default.
- W2016203598 hasConceptScore W2016203598C86803240 @default.
- W2016203598 hasConceptScore W2016203598C89423630 @default.
- W2016203598 hasConceptScore W2016203598C98274493 @default.
- W2016203598 hasConceptScore W2016203598C99454951 @default.
- W2016203598 hasIssue "2" @default.
- W2016203598 hasLocation W20162035981 @default.
- W2016203598 hasLocation W20162035982 @default.
- W2016203598 hasOpenAccess W2016203598 @default.
- W2016203598 hasPrimaryLocation W20162035981 @default.
- W2016203598 hasRelatedWork W1986444812 @default.
- W2016203598 hasRelatedWork W2058046012 @default.
- W2016203598 hasRelatedWork W2144038468 @default.
- W2016203598 hasRelatedWork W2295855342 @default.
- W2016203598 hasRelatedWork W2398893669 @default.
- W2016203598 hasRelatedWork W2402403221 @default.
- W2016203598 hasRelatedWork W2409312553 @default.
- W2016203598 hasRelatedWork W2419858624 @default.
- W2016203598 hasRelatedWork W2472861103 @default.
- W2016203598 hasRelatedWork W7239210 @default.
- W2016203598 hasVolume "67" @default.
- W2016203598 isParatext "false" @default.
- W2016203598 isRetracted "false" @default.
- W2016203598 magId "2016203598" @default.
- W2016203598 workType "article" @default.