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- W2016209502 abstract "The prognostic value of parameters as determined by DNA flow cytometry, in combinationwith other parameters, was assessed in 75 patients with ovarian carcinomas (20% in stage I and II). DNA- index of the tumours appeared to predict mainly the degree of differentiation, since the DNA-index only tended to affect prognosis and low grade tumours were mainly diploid. However, with ascites a non-diploid DNA-index was associated with a significantly lower survival in short-term follow-up. Subgroups with a favourable prognosis were defined by an age of patients ⪯ 40 years, grade 1 tumours, and tumours in stage I or II. Particularly favou rable was the combination of a grade 1 tumour, or a tumour in stage I or II, with percentage of cells in G1 > 85%. Prognostically poor subgroups were defined by an age > 60 years, by grade 2 or 3 tumours and by a clinically advanced stage. The combination of grade 2 or 3., or a clinically advanced stage, with G1-phase fraction ⪯ 85% identified subgroups with a particularly poor prognosis." @default.
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- W2016209502 date "1987-04-01" @default.
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- W2016209502 title "DNA Flow Cytometry, Histological Grade, Stage, and Age as Prognostic Factors in Human Epithelial Ovarian Carcinomas" @default.
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- W2016209502 doi "https://doi.org/10.1016/s0344-0338(87)80106-1" @default.
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