Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016210020> ?p ?o ?g. }
- W2016210020 endingPage "373" @default.
- W2016210020 startingPage "370" @default.
- W2016210020 abstract "A dual-signal amplification method based on two molecular beacons was designed for human hemochromatosis (HFE) gene detection. The two probes, P1 and P2, could resist the exonuclease III (Exo III) digestion due to the 3′-termini protrusion, and could coexist stably with Exo III. In the presence of HFE targets, P1 hybridized with a HFE target to form a duplex DNA with a recessed 3′-hydroxyl termini and then partially digested by Exo III, releasing the HFE target and a residual sequence (X). This X sequence could trigger the digestion of P2 probes with 6-carboxy-fluoresceins and Black Hole Quenchers and then result in the increase of fluorescence intensity. The X sequences were more stable than HFE targets and could cyclically trigger the P2 digestion for a long time even though the HFE targets were digested by Exo III. This method improved the sensitivity and reached 4 orders of magnitude in detection limit, and showed excellent selectivity to discriminate single base mismatched targets well." @default.
- W2016210020 created "2016-06-24" @default.
- W2016210020 creator A5000981879 @default.
- W2016210020 creator A5008171524 @default.
- W2016210020 creator A5046527044 @default.
- W2016210020 creator A5073050892 @default.
- W2016210020 creator A5076946685 @default.
- W2016210020 creator A5082176988 @default.
- W2016210020 creator A5084574203 @default.
- W2016210020 date "2014-11-01" @default.
- W2016210020 modified "2023-10-15" @default.
- W2016210020 title "A dual-signal amplification method for the DNA detection based on exonuclease III" @default.
- W2016210020 cites W1924651386 @default.
- W2016210020 cites W1970900951 @default.
- W2016210020 cites W1973072715 @default.
- W2016210020 cites W1984772187 @default.
- W2016210020 cites W1987565198 @default.
- W2016210020 cites W1991453437 @default.
- W2016210020 cites W2001325691 @default.
- W2016210020 cites W2016494157 @default.
- W2016210020 cites W2022708016 @default.
- W2016210020 cites W2033281624 @default.
- W2016210020 cites W2034171245 @default.
- W2016210020 cites W2034979878 @default.
- W2016210020 cites W2036663746 @default.
- W2016210020 cites W2038436935 @default.
- W2016210020 cites W2062619438 @default.
- W2016210020 cites W2072938372 @default.
- W2016210020 cites W2075567794 @default.
- W2016210020 cites W2096300978 @default.
- W2016210020 cites W2101846762 @default.
- W2016210020 cites W2108013644 @default.
- W2016210020 cites W2131897655 @default.
- W2016210020 cites W2170195185 @default.
- W2016210020 cites W2171892735 @default.
- W2016210020 cites W2313356495 @default.
- W2016210020 cites W2318673848 @default.
- W2016210020 cites W2319343049 @default.
- W2016210020 cites W2325669821 @default.
- W2016210020 doi "https://doi.org/10.1016/j.bios.2014.05.046" @default.
- W2016210020 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24912037" @default.
- W2016210020 hasPublicationYear "2014" @default.
- W2016210020 type Work @default.
- W2016210020 sameAs 2016210020 @default.
- W2016210020 citedByCount "24" @default.
- W2016210020 countsByYear W20162100202014 @default.
- W2016210020 countsByYear W20162100202015 @default.
- W2016210020 countsByYear W20162100202016 @default.
- W2016210020 countsByYear W20162100202017 @default.
- W2016210020 countsByYear W20162100202018 @default.
- W2016210020 countsByYear W20162100202019 @default.
- W2016210020 countsByYear W20162100202020 @default.
- W2016210020 countsByYear W20162100202021 @default.
- W2016210020 countsByYear W20162100202022 @default.
- W2016210020 crossrefType "journal-article" @default.
- W2016210020 hasAuthorship W2016210020A5000981879 @default.
- W2016210020 hasAuthorship W2016210020A5008171524 @default.
- W2016210020 hasAuthorship W2016210020A5046527044 @default.
- W2016210020 hasAuthorship W2016210020A5073050892 @default.
- W2016210020 hasAuthorship W2016210020A5076946685 @default.
- W2016210020 hasAuthorship W2016210020A5082176988 @default.
- W2016210020 hasAuthorship W2016210020A5084574203 @default.
- W2016210020 hasConcept C104317684 @default.
- W2016210020 hasConcept C119128265 @default.
- W2016210020 hasConcept C119203544 @default.
- W2016210020 hasConcept C121332964 @default.
- W2016210020 hasConcept C12554922 @default.
- W2016210020 hasConcept C129312508 @default.
- W2016210020 hasConcept C153911025 @default.
- W2016210020 hasConcept C185581394 @default.
- W2016210020 hasConcept C185592680 @default.
- W2016210020 hasConcept C2777501222 @default.
- W2016210020 hasConcept C2781243718 @default.
- W2016210020 hasConcept C2781357212 @default.
- W2016210020 hasConcept C43617362 @default.
- W2016210020 hasConcept C547475151 @default.
- W2016210020 hasConcept C552990157 @default.
- W2016210020 hasConcept C55493867 @default.
- W2016210020 hasConcept C62520636 @default.
- W2016210020 hasConcept C82381507 @default.
- W2016210020 hasConcept C86803240 @default.
- W2016210020 hasConcept C91881484 @default.
- W2016210020 hasConcept C99611785 @default.
- W2016210020 hasConceptScore W2016210020C104317684 @default.
- W2016210020 hasConceptScore W2016210020C119128265 @default.
- W2016210020 hasConceptScore W2016210020C119203544 @default.
- W2016210020 hasConceptScore W2016210020C121332964 @default.
- W2016210020 hasConceptScore W2016210020C12554922 @default.
- W2016210020 hasConceptScore W2016210020C129312508 @default.
- W2016210020 hasConceptScore W2016210020C153911025 @default.
- W2016210020 hasConceptScore W2016210020C185581394 @default.
- W2016210020 hasConceptScore W2016210020C185592680 @default.
- W2016210020 hasConceptScore W2016210020C2777501222 @default.
- W2016210020 hasConceptScore W2016210020C2781243718 @default.
- W2016210020 hasConceptScore W2016210020C2781357212 @default.
- W2016210020 hasConceptScore W2016210020C43617362 @default.
- W2016210020 hasConceptScore W2016210020C547475151 @default.
- W2016210020 hasConceptScore W2016210020C552990157 @default.