Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016233496> ?p ?o ?g. }
- W2016233496 endingPage "74" @default.
- W2016233496 startingPage "69" @default.
- W2016233496 abstract "An increase in creatinine > 3 μmol/L/h has been suggested to predict death in patients with paraquat self-poisoning and the value of other plasma biomarkers of acute kidney injury has not been assessed. The aim of this study was to validate the predictive value of serial creatinine concentrations and to study the utility of cystatin C and neutrophil gelatinase-associated lipocalin (NGAL) as predictors of outcome in patients with acute paraquat poisoning. The rate of change of creatinine (dCr/dt) and cystatin C (dCyC/dt) concentrations were compared between survivors and deaths. Receiver-operating characteristic (ROC) curves were constructed to determine the best threshold for predicting death. Paraquat was detected in 20 patients and 7 of these died between 18 h and 20 days post-ingestion. The dCr/dt ROC curve had an area of 0.93 and the cut-off was > 4.3 μmol/L/h (sensitivity 100%, specificity 85%, likelihood ratio 7). The dCyC/dt ROC curve had an area of 0.97 and the cutoff was > 0.009 mg/L/h (sensitivity 100%, specificity 91%, likelihood ratio 11). NGAL did not separate survivors from deaths. Death due to acute paraquat poisoning is associated with changes in creatinine and cystatin concentrations. Further validation of these measurements is needed before they can be adopted in guiding intensive treatments." @default.
- W2016233496 created "2016-06-24" @default.
- W2016233496 creator A5018841472 @default.
- W2016233496 creator A5029961929 @default.
- W2016233496 creator A5037239474 @default.
- W2016233496 creator A5040371388 @default.
- W2016233496 creator A5053337156 @default.
- W2016233496 creator A5064284123 @default.
- W2016233496 creator A5073775352 @default.
- W2016233496 date "2011-04-01" @default.
- W2016233496 modified "2023-10-16" @default.
- W2016233496 title "Changes in the concentrations of creatinine, cystatin C and NGAL in patients with acute paraquat self-poisoning" @default.
- W2016233496 cites W1983439718 @default.
- W2016233496 cites W1985126222 @default.
- W2016233496 cites W1987031039 @default.
- W2016233496 cites W1988624801 @default.
- W2016233496 cites W2001469753 @default.
- W2016233496 cites W2016525161 @default.
- W2016233496 cites W2020973044 @default.
- W2016233496 cites W2022271052 @default.
- W2016233496 cites W2034759370 @default.
- W2016233496 cites W2034964131 @default.
- W2016233496 cites W2038473923 @default.
- W2016233496 cites W2071487339 @default.
- W2016233496 cites W2084606456 @default.
- W2016233496 cites W2105958292 @default.
- W2016233496 cites W2107159605 @default.
- W2016233496 cites W2107993105 @default.
- W2016233496 cites W2113705184 @default.
- W2016233496 cites W2124517304 @default.
- W2016233496 cites W2136265986 @default.
- W2016233496 cites W2140736715 @default.
- W2016233496 cites W2143262001 @default.
- W2016233496 cites W2143569590 @default.
- W2016233496 cites W2145713198 @default.
- W2016233496 cites W2146942628 @default.
- W2016233496 cites W2149111967 @default.
- W2016233496 cites W2152575748 @default.
- W2016233496 cites W2163996249 @default.
- W2016233496 cites W2314108031 @default.
- W2016233496 doi "https://doi.org/10.1016/j.toxlet.2011.01.024" @default.
- W2016233496 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3060345" @default.
- W2016233496 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21291964" @default.
- W2016233496 hasPublicationYear "2011" @default.
- W2016233496 type Work @default.
- W2016233496 sameAs 2016233496 @default.
- W2016233496 citedByCount "50" @default.
- W2016233496 countsByYear W20162334962012 @default.
- W2016233496 countsByYear W20162334962013 @default.
- W2016233496 countsByYear W20162334962014 @default.
- W2016233496 countsByYear W20162334962015 @default.
- W2016233496 countsByYear W20162334962017 @default.
- W2016233496 countsByYear W20162334962018 @default.
- W2016233496 countsByYear W20162334962019 @default.
- W2016233496 countsByYear W20162334962020 @default.
- W2016233496 countsByYear W20162334962021 @default.
- W2016233496 countsByYear W20162334962022 @default.
- W2016233496 countsByYear W20162334962023 @default.
- W2016233496 crossrefType "journal-article" @default.
- W2016233496 hasAuthorship W2016233496A5018841472 @default.
- W2016233496 hasAuthorship W2016233496A5029961929 @default.
- W2016233496 hasAuthorship W2016233496A5037239474 @default.
- W2016233496 hasAuthorship W2016233496A5040371388 @default.
- W2016233496 hasAuthorship W2016233496A5053337156 @default.
- W2016233496 hasAuthorship W2016233496A5064284123 @default.
- W2016233496 hasAuthorship W2016233496A5073775352 @default.
- W2016233496 hasBestOaLocation W20162334961 @default.
- W2016233496 hasConcept C126322002 @default.
- W2016233496 hasConcept C126894567 @default.
- W2016233496 hasConcept C159641895 @default.
- W2016233496 hasConcept C185592680 @default.
- W2016233496 hasConcept C2776527163 @default.
- W2016233496 hasConcept C2779548226 @default.
- W2016233496 hasConcept C2780306776 @default.
- W2016233496 hasConcept C2780472472 @default.
- W2016233496 hasConcept C55493867 @default.
- W2016233496 hasConcept C58471807 @default.
- W2016233496 hasConcept C71924100 @default.
- W2016233496 hasConcept C76318530 @default.
- W2016233496 hasConcept C90924648 @default.
- W2016233496 hasConceptScore W2016233496C126322002 @default.
- W2016233496 hasConceptScore W2016233496C126894567 @default.
- W2016233496 hasConceptScore W2016233496C159641895 @default.
- W2016233496 hasConceptScore W2016233496C185592680 @default.
- W2016233496 hasConceptScore W2016233496C2776527163 @default.
- W2016233496 hasConceptScore W2016233496C2779548226 @default.
- W2016233496 hasConceptScore W2016233496C2780306776 @default.
- W2016233496 hasConceptScore W2016233496C2780472472 @default.
- W2016233496 hasConceptScore W2016233496C55493867 @default.
- W2016233496 hasConceptScore W2016233496C58471807 @default.
- W2016233496 hasConceptScore W2016233496C71924100 @default.
- W2016233496 hasConceptScore W2016233496C76318530 @default.
- W2016233496 hasConceptScore W2016233496C90924648 @default.
- W2016233496 hasIssue "1" @default.
- W2016233496 hasLocation W20162334961 @default.
- W2016233496 hasLocation W20162334962 @default.
- W2016233496 hasLocation W20162334963 @default.
- W2016233496 hasOpenAccess W2016233496 @default.