FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016239123> ?p ?o ?g. }

• W2016239123 endingPage "1582" @default.
• W2016239123 startingPage "1576" @default.
• W2016239123 abstract "PET (pre-eclamptic toxaemia), characterized by pregnancy-related hypertension and proteinuria, due to widespread endothelial dysfunction, is a primary cause of maternal morbidity. Altered circulating factors, particularly the VEGF (vascular endothelial growth factor) family of proteins and their receptors, are thought to be key contributors to this disease. Plasma from patients with PET induces numerous cellular and physiological changes in endothelial cells, indicating the presence of a circulating imbalance of the normal plasma constituents. These have been narrowed down to macromolecules of the VEGF family of proteins and receptors. It has been shown that responses of endothelial cells in intact vessels to plasma from patients with pre-eclampsia is VEGF-dependent. It has recently been shown that this may be specific to the VEGF165b isoform, and blocked by addition of recombinant human PlGF (placental growth factor). Taken together with results that show that sVEGFR1 (soluble VEGF receptor 1) levels are insufficient to bind VEGF-A in human plasma from patients with pre-eclampsia, and that other circulating macromolecules bind, but do not inactivate, VEGF-A, this suggests that novel hypotheses involving altered bioavailability of VEGF isoforms resulting from reduced or bound PlGF, or increased sVEGFR1 increasing biological activity of circulating plasma, could be tested. This suggests that knowing how to alter the balance of VEGF family members could prevent endothelial activation, and potentially some symptoms, of pre-eclampsia." @default.
• W2016239123 created "2016-06-24" @default.
• W2016239123 creator A5023058464 @default.
• W2016239123 date "2011-11-21" @default.
• W2016239123 modified "2023-09-23" @default.
• W2016239123 title "An unexpected tail of VEGF and PlGF in pre-eclampsia" @default.
• W2016239123 cites W1479731182 @default.
• W2016239123 cites W1527703884 @default.
• W2016239123 cites W1554964268 @default.
• W2016239123 cites W1969892023 @default.
• W2016239123 cites W1971681123 @default.
• W2016239123 cites W1972588276 @default.
• W2016239123 cites W1980916601 @default.
• W2016239123 cites W1981670613 @default.
• W2016239123 cites W1983186128 @default.
• W2016239123 cites W1983337962 @default.
• W2016239123 cites W1984922128 @default.
• W2016239123 cites W1986469266 @default.
• W2016239123 cites W1988272840 @default.
• W2016239123 cites W1991959440 @default.
• W2016239123 cites W1995016085 @default.
• W2016239123 cites W2002049222 @default.
• W2016239123 cites W2003398004 @default.
• W2016239123 cites W2008908858 @default.
• W2016239123 cites W2010086960 @default.
• W2016239123 cites W2011390136 @default.
• W2016239123 cites W2016906744 @default.
• W2016239123 cites W2017041417 @default.
• W2016239123 cites W2018768026 @default.
• W2016239123 cites W2022114118 @default.
• W2016239123 cites W2022964075 @default.
• W2016239123 cites W2029521699 @default.
• W2016239123 cites W2031525727 @default.
• W2016239123 cites W2033710219 @default.
• W2016239123 cites W2037626596 @default.
• W2016239123 cites W2042702375 @default.
• W2016239123 cites W2044795229 @default.
• W2016239123 cites W2046713495 @default.
• W2016239123 cites W2049746210 @default.
• W2016239123 cites W2055921658 @default.
• W2016239123 cites W2057585528 @default.
• W2016239123 cites W2062052652 @default.
• W2016239123 cites W2062594120 @default.
• W2016239123 cites W2064373198 @default.
• W2016239123 cites W2067020920 @default.
• W2016239123 cites W2067195863 @default.
• W2016239123 cites W2077129920 @default.
• W2016239123 cites W2081734842 @default.
• W2016239123 cites W2085451074 @default.
• W2016239123 cites W2086234009 @default.
• W2016239123 cites W2091512372 @default.
• W2016239123 cites W2093049135 @default.
• W2016239123 cites W2100602740 @default.
• W2016239123 cites W2105311106 @default.
• W2016239123 cites W2114878646 @default.
• W2016239123 cites W2120555366 @default.
• W2016239123 cites W2121247112 @default.
• W2016239123 cites W2123266930 @default.
• W2016239123 cites W2129897241 @default.
• W2016239123 cites W2134648032 @default.
• W2016239123 cites W2135066206 @default.
• W2016239123 cites W2136222990 @default.
• W2016239123 cites W2138657723 @default.
• W2016239123 cites W2142935918 @default.
• W2016239123 cites W2143180984 @default.
• W2016239123 cites W2149309119 @default.
• W2016239123 cites W2149962573 @default.
• W2016239123 cites W2159918536 @default.
• W2016239123 cites W2164971856 @default.
• W2016239123 cites W2166775413 @default.
• W2016239123 cites W2238040093 @default.
• W2016239123 cites W3120856923 @default.
• W2016239123 cites W4235958085 @default.
• W2016239123 cites W4238471969 @default.
• W2016239123 cites W4251118184 @default.
• W2016239123 cites W4251892926 @default.
• W2016239123 doi "https://doi.org/10.1042/bst20110671" @default.
• W2016239123 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3399770" @default.
• W2016239123 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22103490" @default.
• W2016239123 hasPublicationYear "2011" @default.
• W2016239123 type Work @default.
• W2016239123 sameAs 2016239123 @default.
• W2016239123 citedByCount "32" @default.
• W2016239123 countsByYear W20162391232013 @default.
• W2016239123 countsByYear W20162391232014 @default.
• W2016239123 countsByYear W20162391232015 @default.
• W2016239123 countsByYear W20162391232016 @default.
• W2016239123 countsByYear W20162391232017 @default.
• W2016239123 countsByYear W20162391232018 @default.
• W2016239123 countsByYear W20162391232019 @default.
• W2016239123 countsByYear W20162391232021 @default.
• W2016239123 countsByYear W20162391232022 @default.
• W2016239123 crossrefType "journal-article" @default.
• W2016239123 hasAuthorship W2016239123A5023058464 @default.
• W2016239123 hasBestOaLocation W20162391232 @default.
• W2016239123 hasConcept C103041312 @default.
• W2016239123 hasConcept C104317684 @default.
• W2016239123 hasConcept C126322002 @default.

• next