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• W2016255773 abstract "Antigens that do not normally access the cytoplasm of antigen-presenting cells, such as certain tumor and viral antigens, become targets of cytotoxic T lymphocytes (CTLs). Over the past 25 years, substantial evidence has emerged for an 'exogenous' pathway for loading MHC class I molecules. Dendritic cells are potent stimulators of T-cell responses and can induce CD8(+) CTLs by phagocytosis of dead tumor or virus-infected cells. Here, Marie Larsson and colleagues discuss the role of dendritic cells in stimulating MHC class I-restricted T-cell responses by exogenous routes." @default.
• W2016255773 created "2016-06-24" @default.
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• W2016255773 date "2001-03-01" @default.
• W2016255773 modified "2023-10-18" @default.
• W2016255773 title "Dendritic cells resurrect antigens from dead cells" @default.
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• W2016255773 doi "https://doi.org/10.1016/s1471-4906(01)01860-9" @default.
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