FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016260089> ?p ?o ?g. }

• W2016260089 endingPage "441" @default.
• W2016260089 startingPage "411" @default.
• W2016260089 abstract "Symbiosis is found throughout nature, but perhaps nowhere is it more fundamental than mitochondria in all eukaryotes. Since mitochondria were discovered and mechanisms of oxygen reduction characterized, an understanding gradually emerged that these organelles were involved not just in the combustion of oxygen, but also in the sensing of oxygen. While multiple hypotheses exist to explain the mitochondrial involvement in oxygen sensing, key elements are developing that include potassium channels and reactive oxygen species. To understand how mitochondria contribute to oxygen sensing, it is informative to study a model system which is naturally adapted to survive extended periods without oxygen. Amongst air-breathing vertebrates, the most highly adapted are western painted turtles (Chrysemys picta bellii), which overwinter in ice-covered and anoxic water bodies. Through research of this animal, it was postulated that metabolic rate depression is key to anoxic survival and that mitochondrial regulation is a key aspect. When faced with anoxia, excitatory neurotransmitter receptors in turtle brain are inhibited through mitochondrial calcium release, termed “channel arrest”. Simultaneously, inhibitory GABAergic signalling contributes to the “synaptic arrest” of excitatory action potential firing through a pathway dependent on mitochondrial depression of ROS generation. While many pathways are implicated in mitochondrial oxygen sensing in turtles, such as those of adenosine, ATP turnover, and gaseous transmitters, an apparent point of intersection is the mitochondria. In this review we will explore how an organelle that was critical for organismal complexity in an oxygenated world has also become a potentially important oxygen sensor." @default.
• W2016260089 created "2016-06-24" @default.
• W2016260089 creator A5068479553 @default.
• W2016260089 date "1993-08-01" @default.
• W2016260089 modified "2023-09-23" @default.
• W2016260089 title "Making mistakes in Science: Eduard Pflüger, his scientific and professional concept of Physiology, and his unsuccessful theory of diabetes (1903–1910)" @default.
• W2016260089 cites W107401326 @default.
• W2016260089 cites W1566756831 @default.
• W2016260089 cites W16999935 @default.
• W2016260089 cites W1966998500 @default.
• W2016260089 cites W1968103160 @default.
• W2016260089 cites W1969790396 @default.
• W2016260089 cites W1970799573 @default.
• W2016260089 cites W1976368127 @default.
• W2016260089 cites W1977847108 @default.
• W2016260089 cites W1979853054 @default.
• W2016260089 cites W1980130348 @default.
• W2016260089 cites W1995211523 @default.
• W2016260089 cites W2001654743 @default.
• W2016260089 cites W2002739008 @default.
• W2016260089 cites W2003562870 @default.
• W2016260089 cites W2009866212 @default.
• W2016260089 cites W2010915226 @default.
• W2016260089 cites W2014879143 @default.
• W2016260089 cites W2022953289 @default.
• W2016260089 cites W2027131952 @default.
• W2016260089 cites W2035804488 @default.
• W2016260089 cites W2042239433 @default.
• W2016260089 cites W2046512 @default.
• W2016260089 cites W2049231839 @default.
• W2016260089 cites W2053418315 @default.
• W2016260089 cites W2055240393 @default.
• W2016260089 cites W2057015274 @default.
• W2016260089 cites W2058961980 @default.
• W2016260089 cites W2059253946 @default.
• W2016260089 cites W2059595960 @default.
• W2016260089 cites W2061254438 @default.
• W2016260089 cites W2065463476 @default.
• W2016260089 cites W2071457160 @default.
• W2016260089 cites W2073681029 @default.
• W2016260089 cites W2081057999 @default.
• W2016260089 cites W2085803337 @default.
• W2016260089 cites W2092168443 @default.
• W2016260089 cites W2094692607 @default.
• W2016260089 cites W2314787888 @default.
• W2016260089 cites W2316225002 @default.
• W2016260089 cites W2316796070 @default.
• W2016260089 cites W2318764024 @default.
• W2016260089 cites W2319283119 @default.
• W2016260089 cites W2319516692 @default.
• W2016260089 cites W2320708433 @default.
• W2016260089 cites W2321309550 @default.
• W2016260089 cites W2323392543 @default.
• W2016260089 cites W2326444705 @default.
• W2016260089 cites W2944001611 @default.
• W2016260089 cites W2944030347 @default.
• W2016260089 cites W2991082639 @default.
• W2016260089 cites W3135766252 @default.
• W2016260089 cites W40067940 @default.
• W2016260089 cites W4237902788 @default.
• W2016260089 cites W4251110996 @default.
• W2016260089 cites W1985211771 @default.
• W2016260089 doi "https://doi.org/10.1016/0039-3681(93)90036-j" @default.
• W2016260089 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11623289" @default.
• W2016260089 hasPublicationYear "1993" @default.
• W2016260089 type Work @default.
• W2016260089 sameAs 2016260089 @default.
• W2016260089 citedByCount "14" @default.
• W2016260089 countsByYear W20162600892012 @default.
• W2016260089 countsByYear W20162600892014 @default.
• W2016260089 countsByYear W20162600892022 @default.
• W2016260089 crossrefType "journal-article" @default.
• W2016260089 hasAuthorship W2016260089A5068479553 @default.
• W2016260089 hasConcept C112592302 @default.
• W2016260089 hasConcept C169760540 @default.
• W2016260089 hasConcept C170493617 @default.
• W2016260089 hasConcept C17077164 @default.
• W2016260089 hasConcept C178790620 @default.
• W2016260089 hasConcept C185592680 @default.
• W2016260089 hasConcept C28859421 @default.
• W2016260089 hasConcept C48349386 @default.
• W2016260089 hasConcept C540031477 @default.
• W2016260089 hasConcept C55493867 @default.
• W2016260089 hasConcept C61174792 @default.
• W2016260089 hasConcept C66517615 @default.
• W2016260089 hasConcept C86803240 @default.
• W2016260089 hasConcept C95444343 @default.
• W2016260089 hasConceptScore W2016260089C112592302 @default.
• W2016260089 hasConceptScore W2016260089C169760540 @default.
• W2016260089 hasConceptScore W2016260089C170493617 @default.
• W2016260089 hasConceptScore W2016260089C17077164 @default.
• W2016260089 hasConceptScore W2016260089C178790620 @default.
• W2016260089 hasConceptScore W2016260089C185592680 @default.
• W2016260089 hasConceptScore W2016260089C28859421 @default.
• W2016260089 hasConceptScore W2016260089C48349386 @default.
• W2016260089 hasConceptScore W2016260089C540031477 @default.
• W2016260089 hasConceptScore W2016260089C55493867 @default.
• W2016260089 hasConceptScore W2016260089C61174792 @default.

• next