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• W2016262189 abstract "Objectives To investigate the impact of prenatal detection of congenital heart disease on preventing severe preoperative lactacidosis. Design Patients operated upon for congenital heart disease during the first 31 days of life (n = 209) were studied retrospectively, 21 were diagnosed prenatally and 188 patients had not been diagnosed prenatally. Preoperative lactate, pH and base excess were evaluated. Results Differences were noted in preoperative pH (7.28 ± 0.03 vs. 7.24 ± 0.01, P = 0.29), base excess (−5.83 ± 0.64 vs. −6.93 ± 0.46 mmol/L, P = 0.10) and lactate (3.05 ± 0.35 vs. 6.08 ± 0.45 mmol/L, P < 0.001), indicating a significant difference in blood lactate values in favor of the prenatally diagnosed group. Conclusions Prenatal diagnosis of congenital heart disease and the resulting immediate postnatal care prevent lactate increase in the preoperative period of these patients. This may decrease the risk of cerebral damage and result in the patient being in better condition at surgery. Copyright © 2002 ISUOG" @default.
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• W2016262189 date "2002-06-01" @default.
• W2016262189 modified "2023-09-25" @default.
• W2016262189 title "Lactacidosis in the neonate is minimized by prenatal detection of congenital heart disease" @default.
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• W2016262189 doi "https://doi.org/10.1046/j.1469-0705.2002.00714.x" @default.
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