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- W2016266968 abstract "Seven new 17-norpimarane and (9βH)-17-norpimarane diterpenoids, icacinlactones A–G (1–7), were isolated from the tuber of Icacina trichantha. The structures were elucidated by spectroscopic and HRMS techniques, and the absolute configuration of 2 was determined by means of X-ray crystallographic analysis. Compounds 1–7, as well as four known related structures, were evaluated for cytotoxic activity against MDA-MB-435 (human melanoma cancer), MDA-MB-231 (human breast cancer), and OVCAR3 (human ovarian cancer) cell lines. Several of these natural products displayed significant cytotoxic activity, with humirianthenolide C being the most active." @default.
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- W2016266968 date "2015-03-17" @default.
- W2016266968 modified "2023-10-01" @default.
- W2016266968 title "17-Norpimaranes and (9βH)-17-Norpimaranes from the Tuber of <i>Icacina trichantha</i>" @default.
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- W2016266968 doi "https://doi.org/10.1021/np5010328" @default.
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