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- W2016289318 abstract "Most chromosomal rearrangements including the mixed lineage leukemia (MLL) gene are manifested as leukemia and predict a poor prognosis. Although more than 50 MLL-rearrangement partners are characterized, MLL-related leukemogenesis remains to be understood. Here we report a case of a 3-year old boy bearing a novel MLL-rearrangement with the suppressor of actin mutations 1-like (SACM1L) gene in the absence of leukemia. Bone marrow cells harboring the MLL-SACM1L rearrangement appeared during chemotherapy for acute lymphoblastic leukemia with hyperdiploidy and were continuously detected over 7 years without clonal expansion." @default.
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- W2016289318 date "2010-10-01" @default.
- W2016289318 modified "2023-09-25" @default.
- W2016289318 title "Persistent detection of a novel MLL–SACM1L rearrangement in the absence of leukemia" @default.
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- W2016289318 doi "https://doi.org/10.1016/j.leukres.2010.05.001" @default.
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