Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016289380> ?p ?o ?g. }
- W2016289380 abstract "Naturally occurring antioxidants such as vitamin E, beta-carotene, and vitamin C can inhibit the oxidative modification of low density lipoproteins. This action could positively influence the atherosclerotic process and, as a consequence, the progression of coronary heart disease. A wealth of experimental studies provide a sound biological rationale for the mechanisms of action of antioxidants, whereas epidemiologic studies strongly sustain the antioxidant hypothesis. To date, however, clinical trials with beta-carotene supplements have been disappointing, and their use as a preventive intervention for cancer and coronary heart disease should be discouraged. Only scanty data from clinical trials are available for vitamin C. As to vitamin E, discrepant results have been obtained by the Alpha-Tocopherol, Beta Carotene Cancer Prevention Study with a low-dose vitamin E supplementation (50 mg/d) and the Cambridge Heart Antioxidant Study (400-800 mg/d). The results of the GISSI-Prevenzione (300 mg/d) and HOPE (400 mg/d) trials suggest the absence of relevant clinical effects of vitamin E on the risk of cardiovascular events. Currently ongoing are several large-scale clinical trials that will help in clarifying the role of vitamin E in association with other antioxidants in the prevention of atherosclerotic coronary disease." @default.
- W2016289380 created "2016-06-24" @default.
- W2016289380 creator A5008406413 @default.
- W2016289380 creator A5029606867 @default.
- W2016289380 creator A5044932940 @default.
- W2016289380 creator A5060989949 @default.
- W2016289380 creator A5090813987 @default.
- W2016289380 date "2001-01-01" @default.
- W2016289380 modified "2023-10-01" @default.
- W2016289380 title "Antioxidant vitamins and prevention of cardiovascular disease: Epidemiological and clinical trial data" @default.
- W2016289380 cites W113714250 @default.
- W2016289380 cites W1520538169 @default.
- W2016289380 cites W1525444530 @default.
- W2016289380 cites W1589027764 @default.
- W2016289380 cites W1647096666 @default.
- W2016289380 cites W1730700156 @default.
- W2016289380 cites W1857052429 @default.
- W2016289380 cites W1879201657 @default.
- W2016289380 cites W1892215978 @default.
- W2016289380 cites W1894101563 @default.
- W2016289380 cites W1926536076 @default.
- W2016289380 cites W1968073340 @default.
- W2016289380 cites W1968168087 @default.
- W2016289380 cites W1968679020 @default.
- W2016289380 cites W1969146491 @default.
- W2016289380 cites W1970498604 @default.
- W2016289380 cites W1977126756 @default.
- W2016289380 cites W1977651210 @default.
- W2016289380 cites W1977778060 @default.
- W2016289380 cites W1978470067 @default.
- W2016289380 cites W1982562564 @default.
- W2016289380 cites W1984526039 @default.
- W2016289380 cites W1987683192 @default.
- W2016289380 cites W1990046026 @default.
- W2016289380 cites W1996752868 @default.
- W2016289380 cites W1997125030 @default.
- W2016289380 cites W1997693254 @default.
- W2016289380 cites W1997745709 @default.
- W2016289380 cites W1999433683 @default.
- W2016289380 cites W2000548860 @default.
- W2016289380 cites W2003259342 @default.
- W2016289380 cites W2005910570 @default.
- W2016289380 cites W2007447953 @default.
- W2016289380 cites W2012525268 @default.
- W2016289380 cites W2017562075 @default.
- W2016289380 cites W2018402165 @default.
- W2016289380 cites W2024376818 @default.
- W2016289380 cites W2026910087 @default.
- W2016289380 cites W2030720809 @default.
- W2016289380 cites W2030747750 @default.
- W2016289380 cites W2034548788 @default.
- W2016289380 cites W2036159162 @default.
- W2016289380 cites W2036738441 @default.
- W2016289380 cites W2040923416 @default.
- W2016289380 cites W2056155902 @default.
- W2016289380 cites W2056214535 @default.
- W2016289380 cites W2056569028 @default.
- W2016289380 cites W2060204451 @default.
- W2016289380 cites W2061142443 @default.
- W2016289380 cites W2065000758 @default.
- W2016289380 cites W2070803291 @default.
- W2016289380 cites W2070922892 @default.
- W2016289380 cites W2074581135 @default.
- W2016289380 cites W2077423184 @default.
- W2016289380 cites W2078316516 @default.
- W2016289380 cites W2085943063 @default.
- W2016289380 cites W2086440407 @default.
- W2016289380 cites W2087724955 @default.
- W2016289380 cites W2089772634 @default.
- W2016289380 cites W2091429609 @default.
- W2016289380 cites W2096527916 @default.
- W2016289380 cites W2101878571 @default.
- W2016289380 cites W2104127258 @default.
- W2016289380 cites W2104829041 @default.
- W2016289380 cites W2107539572 @default.
- W2016289380 cites W2108670857 @default.
- W2016289380 cites W2113398581 @default.
- W2016289380 cites W2119824831 @default.
- W2016289380 cites W2120618781 @default.
- W2016289380 cites W2122001410 @default.
- W2016289380 cites W2125611568 @default.
- W2016289380 cites W2127332122 @default.
- W2016289380 cites W2127743767 @default.
- W2016289380 cites W2129288396 @default.
- W2016289380 cites W2139755134 @default.
- W2016289380 cites W2141472232 @default.
- W2016289380 cites W2143342811 @default.
- W2016289380 cites W2143841515 @default.
- W2016289380 cites W2144230929 @default.
- W2016289380 cites W2149238262 @default.
- W2016289380 cites W2156620218 @default.
- W2016289380 cites W2158247929 @default.
- W2016289380 cites W2161427454 @default.
- W2016289380 cites W2172351553 @default.
- W2016289380 cites W2192223169 @default.
- W2016289380 cites W2313686482 @default.
- W2016289380 cites W2313837936 @default.
- W2016289380 cites W2315403385 @default.
- W2016289380 cites W2317242858 @default.
- W2016289380 cites W2326202471 @default.