Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016290961> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2016290961 abstract "Human cytochrome P450 3A4 (CYP34A) plays an important role in the metabolism of many endo- and xenomaterials. It also exhibits a substantial interindividual variation in enzymatic activity. It has been shown that the mutant alleles of CYP3A4 encoding inactive/decreased enzymes are largely caused by single nucleotide polymorphisms (SNPs) in the gene sequence. In the present study, with the goal of detecting the known SNPs of CYP3A4, an oligonucleotide microarray was created. A genotyping standard for this microarray was also established using constructed plasmids as standard templates. The 12 SNPs of CYP3A4 in 387 Chinese DNA samples were screened using this oligonucleotide microarray. Three heterozygous subjects of CYP3A4*/*4, 5 heterozygous subjects of CYP3A4*1/*5, 4 heterozygous subjects of CPY3A4*1/6, and 6 heterozygous subjects of CYP3A4*1/*18 were found. The genotyping results of the 18 heterozygous subjects and 12 wild-type subjects were validated by direct sequencing." @default.
- W2016290961 created "2016-06-24" @default.
- W2016290961 creator A5028096678 @default.
- W2016290961 creator A5033280910 @default.
- W2016290961 creator A5036267807 @default.
- W2016290961 creator A5088067045 @default.
- W2016290961 creator A5088209331 @default.
- W2016290961 date "2004-12-01" @default.
- W2016290961 modified "2023-09-26" @default.
- W2016290961 title "Screening of 12 SNPs of CYP3A4 in a Chinese Population Using Oligonucleotide Microarray" @default.
- W2016290961 cites W1910153439 @default.
- W2016290961 cites W1978053566 @default.
- W2016290961 cites W1978618471 @default.
- W2016290961 cites W1983283139 @default.
- W2016290961 cites W1997048544 @default.
- W2016290961 cites W2002445831 @default.
- W2016290961 cites W2037313969 @default.
- W2016290961 cites W2045545694 @default.
- W2016290961 cites W2048793396 @default.
- W2016290961 cites W2090876589 @default.
- W2016290961 cites W2105902511 @default.
- W2016290961 cites W2106109834 @default.
- W2016290961 cites W2140736906 @default.
- W2016290961 cites W2153437712 @default.
- W2016290961 cites W2171409050 @default.
- W2016290961 cites W2414200306 @default.
- W2016290961 cites W4244900749 @default.
- W2016290961 doi "https://doi.org/10.1089/gte.2004.8.411" @default.
- W2016290961 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15684873" @default.
- W2016290961 hasPublicationYear "2004" @default.
- W2016290961 type Work @default.
- W2016290961 sameAs 2016290961 @default.
- W2016290961 citedByCount "14" @default.
- W2016290961 countsByYear W20162909612012 @default.
- W2016290961 countsByYear W20162909612013 @default.
- W2016290961 countsByYear W20162909612014 @default.
- W2016290961 countsByYear W20162909612017 @default.
- W2016290961 crossrefType "journal-article" @default.
- W2016290961 hasAuthorship W2016290961A5028096678 @default.
- W2016290961 hasAuthorship W2016290961A5033280910 @default.
- W2016290961 hasAuthorship W2016290961A5036267807 @default.
- W2016290961 hasAuthorship W2016290961A5088067045 @default.
- W2016290961 hasAuthorship W2016290961A5088209331 @default.
- W2016290961 hasConcept C104317684 @default.
- W2016290961 hasConcept C109650736 @default.
- W2016290961 hasConcept C129312508 @default.
- W2016290961 hasConcept C135763542 @default.
- W2016290961 hasConcept C150194340 @default.
- W2016290961 hasConcept C153209595 @default.
- W2016290961 hasConcept C153911025 @default.
- W2016290961 hasConcept C163691529 @default.
- W2016290961 hasConcept C181199279 @default.
- W2016290961 hasConcept C186836561 @default.
- W2016290961 hasConcept C2908647359 @default.
- W2016290961 hasConcept C31467283 @default.
- W2016290961 hasConcept C526171541 @default.
- W2016290961 hasConcept C54355233 @default.
- W2016290961 hasConcept C55493867 @default.
- W2016290961 hasConcept C71924100 @default.
- W2016290961 hasConcept C86803240 @default.
- W2016290961 hasConcept C95371953 @default.
- W2016290961 hasConcept C99454951 @default.
- W2016290961 hasConceptScore W2016290961C104317684 @default.
- W2016290961 hasConceptScore W2016290961C109650736 @default.
- W2016290961 hasConceptScore W2016290961C129312508 @default.
- W2016290961 hasConceptScore W2016290961C135763542 @default.
- W2016290961 hasConceptScore W2016290961C150194340 @default.
- W2016290961 hasConceptScore W2016290961C153209595 @default.
- W2016290961 hasConceptScore W2016290961C153911025 @default.
- W2016290961 hasConceptScore W2016290961C163691529 @default.
- W2016290961 hasConceptScore W2016290961C181199279 @default.
- W2016290961 hasConceptScore W2016290961C186836561 @default.
- W2016290961 hasConceptScore W2016290961C2908647359 @default.
- W2016290961 hasConceptScore W2016290961C31467283 @default.
- W2016290961 hasConceptScore W2016290961C526171541 @default.
- W2016290961 hasConceptScore W2016290961C54355233 @default.
- W2016290961 hasConceptScore W2016290961C55493867 @default.
- W2016290961 hasConceptScore W2016290961C71924100 @default.
- W2016290961 hasConceptScore W2016290961C86803240 @default.
- W2016290961 hasConceptScore W2016290961C95371953 @default.
- W2016290961 hasConceptScore W2016290961C99454951 @default.
- W2016290961 hasLocation W20162909611 @default.
- W2016290961 hasLocation W20162909612 @default.
- W2016290961 hasOpenAccess W2016290961 @default.
- W2016290961 hasPrimaryLocation W20162909611 @default.
- W2016290961 hasRelatedWork W1663907732 @default.
- W2016290961 hasRelatedWork W1985789223 @default.
- W2016290961 hasRelatedWork W2005471393 @default.
- W2016290961 hasRelatedWork W2016290961 @default.
- W2016290961 hasRelatedWork W2023927857 @default.
- W2016290961 hasRelatedWork W2049974637 @default.
- W2016290961 hasRelatedWork W2121779399 @default.
- W2016290961 hasRelatedWork W2164332050 @default.
- W2016290961 hasRelatedWork W2356514887 @default.
- W2016290961 hasRelatedWork W569138996 @default.
- W2016290961 isParatext "false" @default.
- W2016290961 isRetracted "false" @default.
- W2016290961 magId "2016290961" @default.
- W2016290961 workType "article" @default.