FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016304887> ?p ?o ?g. }

• W2016304887 endingPage "364" @default.
• W2016304887 startingPage "359" @default.
• W2016304887 abstract "Human T cell lymphotropic virus type 1 (HTLV-1) proviral load (PVL) in peripheral blood mononuclear cells (PBMCs) is high in patients with adult T cell leukemia/lymphoma or HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and in some asymptomatic carriers, but fluctuates. Our objectives were to document ranges of HTLV PVL across a broader spectrum of diseases and tissues, to quantify the normal range of intrapatient PVL variability, and to identify which PVL values and changes deserve further investigation. PVL was measured in 191 patients with HTLV-1-associated diseases and in 211 asymptomatic carriers, using real-time quantitative PCR. The intraassay variability increases as viral load decreases: 8% at high load, 17% at medium load, and 33% at low load. The interassay variability is not different from the intraassay. Mean intrapatient CV is 65% (SD 21) in asymptomatic carriers and 59% (SD 22) in HAM/TSP. PVL values varied widely between individuals, but were relatively constant within individuals. High PVL in cerebrospinal fluid (CSF) and lymph nodes (LN) was associated with disease but 57% of asymptomatic carriers had a PVL greater than 1% in PBMCs. Our results suggest that (1) PVL changes falling outside a coefficient of variation of 100% require more detailed assessment, (2) asymptomatic carriers with PVL higher than 10% should undergo more frequent clinical and laboratory monitoring, and (3) HTLV-1 PVL in blood and tissue is helpful in the diagnosis and monitoring of HTLV-1 infection." @default.
• W2016304887 created "2016-06-24" @default.
• W2016304887 creator A5012289865 @default.
• W2016304887 creator A5024704932 @default.
• W2016304887 creator A5088050470 @default.
• W2016304887 date "2013-02-01" @default.
• W2016304887 modified "2023-10-08" @default.
• W2016304887 title "Human T Cell Lymphotropic Virus Type 1 Viral Load Variability and Long-Term Trends in Asymptomatic Carriers and in Patients with Human T Cell Lymphotropic Virus Type 1-Related Diseases" @default.
• W2016304887 cites W1586205537 @default.
• W2016304887 cites W1653607058 @default.
• W2016304887 cites W175886730 @default.
• W2016304887 cites W1976068827 @default.
• W2016304887 cites W1976402310 @default.
• W2016304887 cites W1991941671 @default.
• W2016304887 cites W1997134325 @default.
• W2016304887 cites W1998789189 @default.
• W2016304887 cites W2000541955 @default.
• W2016304887 cites W2016587982 @default.
• W2016304887 cites W2020146098 @default.
• W2016304887 cites W2023030366 @default.
• W2016304887 cites W2036389166 @default.
• W2016304887 cites W2043248836 @default.
• W2016304887 cites W2048022927 @default.
• W2016304887 cites W2068543294 @default.
• W2016304887 cites W2069667541 @default.
• W2016304887 cites W2070549893 @default.
• W2016304887 cites W2075409569 @default.
• W2016304887 cites W2086143621 @default.
• W2016304887 cites W2089048401 @default.
• W2016304887 cites W2091813499 @default.
• W2016304887 cites W2103798850 @default.
• W2016304887 cites W2110834729 @default.
• W2016304887 cites W2125373871 @default.
• W2016304887 cites W2126838772 @default.
• W2016304887 cites W2147544359 @default.
• W2016304887 cites W2152256013 @default.
• W2016304887 cites W2157155233 @default.
• W2016304887 cites W2171170713 @default.
• W2016304887 cites W2243463155 @default.
• W2016304887 cites W2318770038 @default.
• W2016304887 doi "https://doi.org/10.1089/aid.2012.0132" @default.
• W2016304887 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22894552" @default.
• W2016304887 hasPublicationYear "2013" @default.
• W2016304887 type Work @default.
• W2016304887 sameAs 2016304887 @default.
• W2016304887 citedByCount "74" @default.
• W2016304887 countsByYear W20163048872013 @default.
• W2016304887 countsByYear W20163048872014 @default.
• W2016304887 countsByYear W20163048872015 @default.
• W2016304887 countsByYear W20163048872016 @default.
• W2016304887 countsByYear W20163048872017 @default.
• W2016304887 countsByYear W20163048872018 @default.
• W2016304887 countsByYear W20163048872019 @default.
• W2016304887 countsByYear W20163048872020 @default.
• W2016304887 countsByYear W20163048872021 @default.
• W2016304887 countsByYear W20163048872022 @default.
• W2016304887 countsByYear W20163048872023 @default.
• W2016304887 crossrefType "journal-article" @default.
• W2016304887 hasAuthorship W2016304887A5012289865 @default.
• W2016304887 hasAuthorship W2016304887A5024704932 @default.
• W2016304887 hasAuthorship W2016304887A5088050470 @default.
• W2016304887 hasConcept C118552586 @default.
• W2016304887 hasConcept C137061746 @default.
• W2016304887 hasConcept C137916694 @default.
• W2016304887 hasConcept C142462285 @default.
• W2016304887 hasConcept C142724271 @default.
• W2016304887 hasConcept C159047783 @default.
• W2016304887 hasConcept C202751555 @default.
• W2016304887 hasConcept C203014093 @default.
• W2016304887 hasConcept C2522874641 @default.
• W2016304887 hasConcept C2776185481 @default.
• W2016304887 hasConcept C2776238826 @default.
• W2016304887 hasConcept C2776368728 @default.
• W2016304887 hasConcept C2776392238 @default.
• W2016304887 hasConcept C2776913467 @default.
• W2016304887 hasConcept C2777604421 @default.
• W2016304887 hasConcept C2777910003 @default.
• W2016304887 hasConcept C2780727368 @default.
• W2016304887 hasConcept C2780775167 @default.
• W2016304887 hasConcept C55493867 @default.
• W2016304887 hasConcept C71924100 @default.
• W2016304887 hasConcept C86803240 @default.
• W2016304887 hasConceptScore W2016304887C118552586 @default.
• W2016304887 hasConceptScore W2016304887C137061746 @default.
• W2016304887 hasConceptScore W2016304887C137916694 @default.
• W2016304887 hasConceptScore W2016304887C142462285 @default.
• W2016304887 hasConceptScore W2016304887C142724271 @default.
• W2016304887 hasConceptScore W2016304887C159047783 @default.
• W2016304887 hasConceptScore W2016304887C202751555 @default.
• W2016304887 hasConceptScore W2016304887C203014093 @default.
• W2016304887 hasConceptScore W2016304887C2522874641 @default.
• W2016304887 hasConceptScore W2016304887C2776185481 @default.
• W2016304887 hasConceptScore W2016304887C2776238826 @default.
• W2016304887 hasConceptScore W2016304887C2776368728 @default.
• W2016304887 hasConceptScore W2016304887C2776392238 @default.
• W2016304887 hasConceptScore W2016304887C2776913467 @default.
• W2016304887 hasConceptScore W2016304887C2777604421 @default.
• W2016304887 hasConceptScore W2016304887C2777910003 @default.

• next