FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016307344> ?p ?o ?g. }

• W2016307344 endingPage "355" @default.
• W2016307344 startingPage "354" @default.
• W2016307344 abstract "BACKGROUND AND PURPOSE: Increases in apparent diffusion coefficient (ADC) from diffusion-weighted (DW) imaging are thought to be due to axonal disruption, and changes have been well documented in multiple sclerosis lesions. DW imaging of the optic nerves, however, presents many challenges. The goal of this study was to measure ADC in patients with optic neuritis by using zonal oblique multisection echoplanar imaging. METHODS: The optic nerves of eighteen patients who had experienced an attack of optic neuritis 1 year previously and 11 control subjects were imaged with the diffusion sequence (usable data were available from 16 patients and 10 control subjects). The orbital optic nerves were segmented by a blinded observer by using a computer-assisted threshold-based contouring technique, and the mean ADC was determined. RESULTS: The mean ADC from diseased optic nerves was 1324 10 6 mm 2 /s, compared with 990 10 6 mm 2 /s from healthy contralateral optic nerves (P .005 versus diseased optic nerves) and 928 10 6 mm 2 /s from control optic nerves (P .006 versus diseased optic nerves and P .40 versus healthy contralateral optic nerves). The diseased optic nerve ADC correlated with both visual (e.g., rS 0.73; P .001 for logMAR visual acuity) and electrophysiological parameters (e.g., rS 0.57, P .021 for visual evoked potential central field amplitude [VEP]). CONCLUSION: It has been possible to apply DW imaging in a patient population, and, in the chronic phase following optic neuritis, the correlation of mean ADC with the clinical and electrophysiological parameters suggests that the ADC is giving a surrogate measure of axonal disruption in the chronic, postinflammatory optic nerve lesion. Diffusion of water molecules in vivo is affected by the structure of the tissue. White matter tracts are made up of bundles of tightly packed axons. Diffusion of water occurs preferentially along the orientation of the axons because cell membranes act as barriers to diffusion. Diffusion-weighted (DW) imaging refers to" @default.
• W2016307344 created "2016-06-24" @default.
• W2016307344 creator A5018507580 @default.
• W2016307344 creator A5022913075 @default.
• W2016307344 creator A5030792843 @default.
• W2016307344 creator A5075361688 @default.
• W2016307344 creator A5079179983 @default.
• W2016307344 creator A5083168810 @default.
• W2016307344 creator A5086868602 @default.
• W2016307344 date "2005-08-01" @default.
• W2016307344 modified "2023-10-18" @default.
• W2016307344 title "Optic nerve diffusion measurement from diffusion-weighted imaging in optic neuritis" @default.
• W2016307344 cites W141585252 @default.
• W2016307344 cites W1964802316 @default.
• W2016307344 cites W1975338529 @default.
• W2016307344 cites W1995086395 @default.
• W2016307344 cites W1995513670 @default.
• W2016307344 cites W1995591510 @default.
• W2016307344 cites W1996441019 @default.
• W2016307344 cites W2001979075 @default.
• W2016307344 cites W2007176228 @default.
• W2016307344 cites W2008279330 @default.
• W2016307344 cites W2020332292 @default.
• W2016307344 cites W2046810624 @default.
• W2016307344 cites W2048844243 @default.
• W2016307344 cites W2050468619 @default.
• W2016307344 cites W2074373813 @default.
• W2016307344 cites W2084761689 @default.
• W2016307344 cites W2086649533 @default.
• W2016307344 cites W2117963842 @default.
• W2016307344 cites W2122988309 @default.
• W2016307344 cites W2130355701 @default.
• W2016307344 cites W2143862196 @default.
• W2016307344 cites W2162764399 @default.
• W2016307344 cites W2403831170 @default.
• W2016307344 cites W83571168 @default.
• W2016307344 doi "https://doi.org/10.1016/j.ajo.2005.06.012" @default.
• W2016307344 hasPublicationYear "2005" @default.
• W2016307344 type Work @default.
• W2016307344 sameAs 2016307344 @default.
• W2016307344 citedByCount "6" @default.
• W2016307344 countsByYear W20163073442013 @default.
• W2016307344 countsByYear W20163073442015 @default.
• W2016307344 countsByYear W20163073442016 @default.
• W2016307344 countsByYear W20163073442017 @default.
• W2016307344 countsByYear W20163073442018 @default.
• W2016307344 crossrefType "journal-article" @default.
• W2016307344 hasAuthorship W2016307344A5018507580 @default.
• W2016307344 hasAuthorship W2016307344A5022913075 @default.
• W2016307344 hasAuthorship W2016307344A5030792843 @default.
• W2016307344 hasAuthorship W2016307344A5075361688 @default.
• W2016307344 hasAuthorship W2016307344A5079179983 @default.
• W2016307344 hasAuthorship W2016307344A5083168810 @default.
• W2016307344 hasAuthorship W2016307344A5086868602 @default.
• W2016307344 hasBestOaLocation W20163073442 @default.
• W2016307344 hasConcept C118487528 @default.
• W2016307344 hasConcept C118552586 @default.
• W2016307344 hasConcept C121332964 @default.
• W2016307344 hasConcept C126838900 @default.
• W2016307344 hasConcept C141071460 @default.
• W2016307344 hasConcept C143409427 @default.
• W2016307344 hasConcept C149550507 @default.
• W2016307344 hasConcept C2776028648 @default.
• W2016307344 hasConcept C2776572573 @default.
• W2016307344 hasConcept C2780640218 @default.
• W2016307344 hasConcept C2780837183 @default.
• W2016307344 hasConcept C2910842333 @default.
• W2016307344 hasConcept C69357855 @default.
• W2016307344 hasConcept C71924100 @default.
• W2016307344 hasConcept C97355855 @default.
• W2016307344 hasConceptScore W2016307344C118487528 @default.
• W2016307344 hasConceptScore W2016307344C118552586 @default.
• W2016307344 hasConceptScore W2016307344C121332964 @default.
• W2016307344 hasConceptScore W2016307344C126838900 @default.
• W2016307344 hasConceptScore W2016307344C141071460 @default.
• W2016307344 hasConceptScore W2016307344C143409427 @default.
• W2016307344 hasConceptScore W2016307344C149550507 @default.
• W2016307344 hasConceptScore W2016307344C2776028648 @default.
• W2016307344 hasConceptScore W2016307344C2776572573 @default.
• W2016307344 hasConceptScore W2016307344C2780640218 @default.
• W2016307344 hasConceptScore W2016307344C2780837183 @default.
• W2016307344 hasConceptScore W2016307344C2910842333 @default.
• W2016307344 hasConceptScore W2016307344C69357855 @default.
• W2016307344 hasConceptScore W2016307344C71924100 @default.
• W2016307344 hasConceptScore W2016307344C97355855 @default.
• W2016307344 hasIssue "2" @default.
• W2016307344 hasLocation W20163073441 @default.
• W2016307344 hasLocation W20163073442 @default.
• W2016307344 hasOpenAccess W2016307344 @default.
• W2016307344 hasPrimaryLocation W20163073441 @default.
• W2016307344 hasRelatedWork W1593567439 @default.
• W2016307344 hasRelatedWork W2016307344 @default.
• W2016307344 hasRelatedWork W2046922430 @default.
• W2016307344 hasRelatedWork W2322134919 @default.
• W2016307344 hasRelatedWork W2414948315 @default.
• W2016307344 hasRelatedWork W2415981061 @default.
• W2016307344 hasRelatedWork W2424875500 @default.
• W2016307344 hasRelatedWork W39517347 @default.

• next