FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016321388> ?p ?o ?g. }

• W2016321388 endingPage "1232" @default.
• W2016321388 startingPage "1225" @default.
• W2016321388 abstract "Summary Background and aim : Data from renal transplant and rheumatoid arthritis patients suggest that there is an increased risk of malignancy after treatment with azathioprine. Whether this is true for patients with inflammatory bowel disease remains uncertain. Method : A retrospective review of clinical notes was performed. Results : Azathioprine was given to 626 of 2204 patients (855 with Crohn's disease and 1349 with ulcerative colitis). The mean total duration of azathioprine use was 27 months. The mean follow‐up from diagnosis was 13.7 years and the mean follow‐up from the start of azathioprine treatment was 6.9 years. Thirty‐one cancers were observed in 30 patients treated with azathioprine (4.5%) and 77 cancers were observed in 70 patients not treated with azathioprine (4.5%; P =N.S.). Logistic regression analysis (including in the model the age, sex, diagnosis and extent of disease) showed that treatment with azathioprine did not significantly affect the risk of the development of cancer. Eight patients had lymphoma; three had been given azathioprine ( P =N.S.). For patients with ulcerative colitis, the number of colorectal cancers (including high‐grade dysplasia) in patients given azathioprine was eight of 355 (2.2%), compared with 28 of 994 (2.8%) for patients not given azathioprine ( P =N.S.). The cumulative risk of colorectal cancer or dysplasia/dysplasia‐associated lesion or mass (adjusted to exclude post‐colectomy patients) after 10, 20, 30 and 40 years ofulcerative colitis was 0.4%, 1.3%, 9%and 15.5%, respectively. Conclusion : No increased risk of cancer diagnosis following azathioprine treatment was observed." @default.
• W2016321388 created "2016-06-24" @default.
• W2016321388 creator A5023170379 @default.
• W2016321388 creator A5046380772 @default.
• W2016321388 creator A5052814011 @default.
• W2016321388 creator A5064989585 @default.
• W2016321388 date "2002-07-01" @default.
• W2016321388 modified "2023-10-17" @default.
• W2016321388 title "Long-term risk of malignancy after treatment of inflammatory bowel disease with azathioprine" @default.
• W2016321388 cites W1985465215 @default.
• W2016321388 cites W1991329138 @default.
• W2016321388 cites W1995372822 @default.
• W2016321388 cites W2000925186 @default.
• W2016321388 cites W2005097349 @default.
• W2016321388 cites W2017130791 @default.
• W2016321388 cites W2024293518 @default.
• W2016321388 cites W2025343624 @default.
• W2016321388 cites W2043258441 @default.
• W2016321388 cites W2045123507 @default.
• W2016321388 cites W2079046187 @default.
• W2016321388 cites W2089391684 @default.
• W2016321388 cites W2093533256 @default.
• W2016321388 cites W2115205193 @default.
• W2016321388 cites W2130078150 @default.
• W2016321388 cites W2137715127 @default.
• W2016321388 cites W2142612410 @default.
• W2016321388 cites W2152724099 @default.
• W2016321388 cites W2158006783 @default.
• W2016321388 cites W2314055620 @default.
• W2016321388 cites W2614197161 @default.
• W2016321388 cites W4210811641 @default.
• W2016321388 cites W4252431323 @default.
• W2016321388 cites W4376595875 @default.
• W2016321388 doi "https://doi.org/10.1046/j.1365-2036.2002.01297.x" @default.
• W2016321388 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12144571" @default.
• W2016321388 hasPublicationYear "2002" @default.
• W2016321388 type Work @default.
• W2016321388 sameAs 2016321388 @default.
• W2016321388 citedByCount "190" @default.
• W2016321388 countsByYear W20163213882012 @default.
• W2016321388 countsByYear W20163213882013 @default.
• W2016321388 countsByYear W20163213882014 @default.
• W2016321388 countsByYear W20163213882015 @default.
• W2016321388 countsByYear W20163213882016 @default.
• W2016321388 countsByYear W20163213882017 @default.
• W2016321388 countsByYear W20163213882018 @default.
• W2016321388 countsByYear W20163213882019 @default.
• W2016321388 countsByYear W20163213882020 @default.
• W2016321388 countsByYear W20163213882021 @default.
• W2016321388 countsByYear W20163213882022 @default.
• W2016321388 countsByYear W20163213882023 @default.
• W2016321388 crossrefType "journal-article" @default.
• W2016321388 hasAuthorship W2016321388A5023170379 @default.
• W2016321388 hasAuthorship W2016321388A5046380772 @default.
• W2016321388 hasAuthorship W2016321388A5052814011 @default.
• W2016321388 hasAuthorship W2016321388A5064989585 @default.
• W2016321388 hasBestOaLocation W20163213881 @default.
• W2016321388 hasConcept C121608353 @default.
• W2016321388 hasConcept C126322002 @default.
• W2016321388 hasConcept C141071460 @default.
• W2016321388 hasConcept C2775894508 @default.
• W2016321388 hasConcept C2776667177 @default.
• W2016321388 hasConcept C2776760755 @default.
• W2016321388 hasConcept C2778260677 @default.
• W2016321388 hasConcept C2779134260 @default.
• W2016321388 hasConcept C2779399171 @default.
• W2016321388 hasConcept C2780479503 @default.
• W2016321388 hasConcept C71924100 @default.
• W2016321388 hasConcept C90924648 @default.
• W2016321388 hasConceptScore W2016321388C121608353 @default.
• W2016321388 hasConceptScore W2016321388C126322002 @default.
• W2016321388 hasConceptScore W2016321388C141071460 @default.
• W2016321388 hasConceptScore W2016321388C2775894508 @default.
• W2016321388 hasConceptScore W2016321388C2776667177 @default.
• W2016321388 hasConceptScore W2016321388C2776760755 @default.
• W2016321388 hasConceptScore W2016321388C2778260677 @default.
• W2016321388 hasConceptScore W2016321388C2779134260 @default.
• W2016321388 hasConceptScore W2016321388C2779399171 @default.
• W2016321388 hasConceptScore W2016321388C2780479503 @default.
• W2016321388 hasConceptScore W2016321388C71924100 @default.
• W2016321388 hasConceptScore W2016321388C90924648 @default.
• W2016321388 hasIssue "7" @default.
• W2016321388 hasLocation W20163213881 @default.
• W2016321388 hasLocation W20163213882 @default.
• W2016321388 hasOpenAccess W2016321388 @default.
• W2016321388 hasPrimaryLocation W20163213881 @default.
• W2016321388 hasRelatedWork W178943794 @default.
• W2016321388 hasRelatedWork W1978906444 @default.
• W2016321388 hasRelatedWork W203984136 @default.
• W2016321388 hasRelatedWork W2053811539 @default.
• W2016321388 hasRelatedWork W2124185266 @default.
• W2016321388 hasRelatedWork W2332632286 @default.
• W2016321388 hasRelatedWork W2923016442 @default.
• W2016321388 hasRelatedWork W3002404702 @default.
• W2016321388 hasRelatedWork W4248730963 @default.
• W2016321388 hasRelatedWork W4307724689 @default.
• W2016321388 hasVolume "16" @default.
• W2016321388 isParatext "false" @default.

• next