Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016323275> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2016323275 endingPage "310" @default.
- W2016323275 startingPage "305" @default.
- W2016323275 abstract "Aims The present study was initiated by a very recent histochemical observation of lipid accumulation in the renal cortex of a woman who died in a diabetic coma. Two older reports of lipid accumulation in the kidneys of patients who died, most likely in a state of non-regulated diabetes, supported this observation. We have examined whether lipid accumulation in the renal cortex is characteristic of diabetic coma and, if so, which type of lipid accumulates. Methods Three groups were studied. Ten subjects who died in a diabetic coma, eight diabetics who died of known causes unrelated to diabetes, and seven normal control subjects without any diagnosed diabetes who died of known causes. All were subjected to histological examination for lipid accumulation in the renal cortex. Detailed analysis of cortex lipids was performed for two of the subjects who died in a diabetic coma and all diabetic controls as well as non-diabetic control subjects. Results All subjects who died in a diabetic coma showed vacuolar lesions staining strongly for lipid in the proximal tubules. Neither normal controls nor non-coma diabetics showed these lesions. Compared with normal controls, renal cortex lipid was about tripled in the two analysed diabetic coma subjects due to 60–100-fold increases of triglycerides. The non-coma diabetics did not differ from the other controls with respect to triglycerides or other types of lipid, except that cholesteryl esters were elevated, though still a quantitatively minor component. Conclusion Our findings strongly indicate that vacuolar lesions in the proximal tubules are characteristic of diabetic coma and that they are caused by accumulated triglycer-ides. Therefore, histological examination of renal cortex using a lipid stain may be a useful forensic tool in establishing diabetic coma as the cause of death." @default.
- W2016323275 created "2016-06-24" @default.
- W2016323275 creator A5012798925 @default.
- W2016323275 creator A5037754638 @default.
- W2016323275 creator A5055267907 @default.
- W2016323275 creator A5073459736 @default.
- W2016323275 date "2003-08-01" @default.
- W2016323275 modified "2023-09-27" @default.
- W2016323275 title "Accumulation of triglycerides in the proximal tubule of the kidney in diabetic coma" @default.
- W2016323275 cites W1513897103 @default.
- W2016323275 cites W1985756954 @default.
- W2016323275 cites W1986605833 @default.
- W2016323275 cites W2036019651 @default.
- W2016323275 cites W2036788087 @default.
- W2016323275 cites W2039999119 @default.
- W2016323275 cites W2040735261 @default.
- W2016323275 cites W2050172715 @default.
- W2016323275 cites W2074865501 @default.
- W2016323275 cites W2087480834 @default.
- W2016323275 cites W2093562894 @default.
- W2016323275 cites W2152311269 @default.
- W2016323275 cites W2332825057 @default.
- W2016323275 cites W36612387 @default.
- W2016323275 doi "https://doi.org/10.1080/0031302031000150551" @default.
- W2016323275 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12959765" @default.
- W2016323275 hasPublicationYear "2003" @default.
- W2016323275 type Work @default.
- W2016323275 sameAs 2016323275 @default.
- W2016323275 citedByCount "26" @default.
- W2016323275 countsByYear W20163232752012 @default.
- W2016323275 countsByYear W20163232752013 @default.
- W2016323275 countsByYear W20163232752014 @default.
- W2016323275 countsByYear W20163232752015 @default.
- W2016323275 countsByYear W20163232752016 @default.
- W2016323275 countsByYear W20163232752017 @default.
- W2016323275 countsByYear W20163232752021 @default.
- W2016323275 countsByYear W20163232752022 @default.
- W2016323275 countsByYear W20163232752023 @default.
- W2016323275 crossrefType "journal-article" @default.
- W2016323275 hasAuthorship W2016323275A5012798925 @default.
- W2016323275 hasAuthorship W2016323275A5037754638 @default.
- W2016323275 hasAuthorship W2016323275A5055267907 @default.
- W2016323275 hasAuthorship W2016323275A5073459736 @default.
- W2016323275 hasConcept C100136789 @default.
- W2016323275 hasConcept C120665830 @default.
- W2016323275 hasConcept C121332964 @default.
- W2016323275 hasConcept C126322002 @default.
- W2016323275 hasConcept C134018914 @default.
- W2016323275 hasConcept C142724271 @default.
- W2016323275 hasConcept C169760540 @default.
- W2016323275 hasConcept C2777348757 @default.
- W2016323275 hasConcept C2778577996 @default.
- W2016323275 hasConcept C2779996878 @default.
- W2016323275 hasConcept C2780091579 @default.
- W2016323275 hasConcept C555293320 @default.
- W2016323275 hasConcept C71924100 @default.
- W2016323275 hasConcept C86803240 @default.
- W2016323275 hasConceptScore W2016323275C100136789 @default.
- W2016323275 hasConceptScore W2016323275C120665830 @default.
- W2016323275 hasConceptScore W2016323275C121332964 @default.
- W2016323275 hasConceptScore W2016323275C126322002 @default.
- W2016323275 hasConceptScore W2016323275C134018914 @default.
- W2016323275 hasConceptScore W2016323275C142724271 @default.
- W2016323275 hasConceptScore W2016323275C169760540 @default.
- W2016323275 hasConceptScore W2016323275C2777348757 @default.
- W2016323275 hasConceptScore W2016323275C2778577996 @default.
- W2016323275 hasConceptScore W2016323275C2779996878 @default.
- W2016323275 hasConceptScore W2016323275C2780091579 @default.
- W2016323275 hasConceptScore W2016323275C555293320 @default.
- W2016323275 hasConceptScore W2016323275C71924100 @default.
- W2016323275 hasConceptScore W2016323275C86803240 @default.
- W2016323275 hasIssue "4" @default.
- W2016323275 hasLocation W20163232751 @default.
- W2016323275 hasLocation W20163232752 @default.
- W2016323275 hasOpenAccess W2016323275 @default.
- W2016323275 hasPrimaryLocation W20163232751 @default.
- W2016323275 hasRelatedWork W2016323275 @default.
- W2016323275 hasRelatedWork W2042033030 @default.
- W2016323275 hasRelatedWork W2070511355 @default.
- W2016323275 hasRelatedWork W2082456910 @default.
- W2016323275 hasRelatedWork W2098742882 @default.
- W2016323275 hasRelatedWork W2127085070 @default.
- W2016323275 hasRelatedWork W2319873196 @default.
- W2016323275 hasRelatedWork W2400445066 @default.
- W2016323275 hasRelatedWork W4238396739 @default.
- W2016323275 hasRelatedWork W2042893290 @default.
- W2016323275 hasVolume "35" @default.
- W2016323275 isParatext "false" @default.
- W2016323275 isRetracted "false" @default.
- W2016323275 magId "2016323275" @default.
- W2016323275 workType "article" @default.