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- W2016329013 abstract "Les macrophages possèdent à leur surface différents récepteurs membranaires dont les interactions avec leurs ligands spécifiques sont autant de signaux intervenant dans la modulation des activités macrophagiques. Celles-ci sont fort nombreuses, et à la phagocytose, découverte il y a 100 ans par Elie Metchnikoff, sont venus s'ajouter un grand nombre de fonctions attribuées aux macrophages : participation au cours des mécanismes intlammatoires, élimination de cellules tumorales, production de facteurs humoraux, rôle au cours de la régulation de la réponse immune, etc. De même, au cours des phénomènes d'hypersensibilité immédiate, différents auteurs ont montré la participation de macrophages à la suite de leur interaction avec l'antigène (allergène), les complexes immuns à IgE, des adjuvants, l'histamine ou bien encore des médiateurs induits par l'histamine. Macrophages bear on their membrane different receptors whose interactions with their specific ligands lead to signals involved in the modulation of their activities. These multiple activities, and a large number of macrophagic functions have been demonstrated since the discovery of phagocytosis, 100 years ago : i.e. involvement during inflammatory mechanisms, elimination of tumor cells, production of humoral factors, participation during the regulation of the immune response… As well, during immediate hypersensitivity phenomenon, different authors have shown the role of macrophages, following their interaction with allergens, IgE-immune complexes, adjuvants histamine or histamine-induced factors." @default.
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- W2016329013 title "Macrophages et hypersensibilité immédiate" @default.
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