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- W2016335937 abstract "Of the various metabolic effects produced in yeast cells by the cationic detergent, benzalkonium, the most pronounced is the inhibition of the pathway of respiration of two-carbon compounds. Less sensitive is the fermentation of glucose and the respiration of three-carbon substances. Because glucose is normally respired via two pathways, the formation of two-carbon substances and the direct oxidation of pyruvate, benzalkonium disturbs the normal pattern of its metabolism. The R.Q. is markedly elevated. The “extra CO2” production is paralleled by an appearance of ethyl alcohol. This action of benzalkonium on glucose can be largely duplicated by over-loading the system through addition of two-carbon compounds such as ethyl alcohol, acetaldehyde or acetate, or by excessive concentrations of glucose itself. The detergent also causes an increase in the total amount of O2 consumed for a given amount of substrate and a change in the R.Q. for the respiration of alcohol or acetaldehyde. These actions are related to the inhibition of carbohydrate assimilation." @default.
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- W2016335937 title "The mechanism of stimulation of aerobic fermentation in yeast by a quaternary ammonium detergent" @default.
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- W2016335937 doi "https://doi.org/10.1016/0006-2952(61)90103-4" @default.
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