Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016341609> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2016341609 endingPage "756" @default.
- W2016341609 startingPage "753" @default.
- W2016341609 abstract "A new procedure for the simultaneous staining of membranous antigens, such as tyrosine kinase-type cell surface receptor HER2 (c-erbB2), and the corresponding chromosome (chromosome 17 for c-erbB2) in the same cell for use in examining pathology archives is presented. A multistep procedure involving microwave-assisted fluorescence in situ hybridization and immunofluorescence yielded cell images having c-erbB2 on the membrane and genomic signals from the chromosome 17 centromere and the c-erbB2 locus. Furthermore, a combination of microwave-assisted chromogenic in situ hybridization and immunohistochemistry found colorized signals from both chromosome 17 centromere in the nuclei and c-erbB2 on the membranes of individual cells. Quantitative image analysis further confirmed the presence of a significantly stronger c-erbB2 immunoreactivity on cells containing three or more signals from chromosome 17 than from those with less than three signals. It was possible to extend the constellation of cell surface markers and corresponding chromosomes or locus-specific makers to several other genes including CDH1. In this case, the disappearances of CDH1 expression, a CDH1 locus signal, and a centromere enumeration probe (CEP) 16 signal were simultaneously demonstrated in the less-adhesive tumor cells. Thus, it is believed that this procedure might pave the way for exploiting pathology archives for the genotype-phenotype analysis of individual cells." @default.
- W2016341609 created "2016-06-24" @default.
- W2016341609 creator A5000601994 @default.
- W2016341609 creator A5008405600 @default.
- W2016341609 creator A5019586725 @default.
- W2016341609 creator A5022478941 @default.
- W2016341609 creator A5038274081 @default.
- W2016341609 creator A5040737511 @default.
- W2016341609 creator A5041039983 @default.
- W2016341609 creator A5063851467 @default.
- W2016341609 creator A5074349263 @default.
- W2016341609 creator A5077931070 @default.
- W2016341609 creator A5081890105 @default.
- W2016341609 date "2005-11-15" @default.
- W2016341609 modified "2023-10-12" @default.
- W2016341609 title "Simultaneous imaging of membrane antigen and the corresponding chromosomal locus in pathology archives" @default.
- W2016341609 cites W1963483773 @default.
- W2016341609 cites W1969404254 @default.
- W2016341609 cites W1994242106 @default.
- W2016341609 cites W2030095488 @default.
- W2016341609 cites W2075222599 @default.
- W2016341609 cites W2083554392 @default.
- W2016341609 cites W2128495081 @default.
- W2016341609 cites W2155430390 @default.
- W2016341609 doi "https://doi.org/10.1111/j.1440-1827.2005.01901.x" @default.
- W2016341609 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16287489" @default.
- W2016341609 hasPublicationYear "2005" @default.
- W2016341609 type Work @default.
- W2016341609 sameAs 2016341609 @default.
- W2016341609 citedByCount "8" @default.
- W2016341609 countsByYear W20163416092012 @default.
- W2016341609 crossrefType "journal-article" @default.
- W2016341609 hasAuthorship W2016341609A5000601994 @default.
- W2016341609 hasAuthorship W2016341609A5008405600 @default.
- W2016341609 hasAuthorship W2016341609A5019586725 @default.
- W2016341609 hasAuthorship W2016341609A5022478941 @default.
- W2016341609 hasAuthorship W2016341609A5038274081 @default.
- W2016341609 hasAuthorship W2016341609A5040737511 @default.
- W2016341609 hasAuthorship W2016341609A5041039983 @default.
- W2016341609 hasAuthorship W2016341609A5063851467 @default.
- W2016341609 hasAuthorship W2016341609A5074349263 @default.
- W2016341609 hasAuthorship W2016341609A5077931070 @default.
- W2016341609 hasAuthorship W2016341609A5081890105 @default.
- W2016341609 hasConcept C104317684 @default.
- W2016341609 hasConcept C1491633281 @default.
- W2016341609 hasConcept C149402561 @default.
- W2016341609 hasConcept C150194340 @default.
- W2016341609 hasConcept C153911025 @default.
- W2016341609 hasConcept C2776391639 @default.
- W2016341609 hasConcept C2777542201 @default.
- W2016341609 hasConcept C30481170 @default.
- W2016341609 hasConcept C54355233 @default.
- W2016341609 hasConcept C63491729 @default.
- W2016341609 hasConcept C81439078 @default.
- W2016341609 hasConcept C84597430 @default.
- W2016341609 hasConcept C86803240 @default.
- W2016341609 hasConceptScore W2016341609C104317684 @default.
- W2016341609 hasConceptScore W2016341609C1491633281 @default.
- W2016341609 hasConceptScore W2016341609C149402561 @default.
- W2016341609 hasConceptScore W2016341609C150194340 @default.
- W2016341609 hasConceptScore W2016341609C153911025 @default.
- W2016341609 hasConceptScore W2016341609C2776391639 @default.
- W2016341609 hasConceptScore W2016341609C2777542201 @default.
- W2016341609 hasConceptScore W2016341609C30481170 @default.
- W2016341609 hasConceptScore W2016341609C54355233 @default.
- W2016341609 hasConceptScore W2016341609C63491729 @default.
- W2016341609 hasConceptScore W2016341609C81439078 @default.
- W2016341609 hasConceptScore W2016341609C84597430 @default.
- W2016341609 hasConceptScore W2016341609C86803240 @default.
- W2016341609 hasIssue "12" @default.
- W2016341609 hasLocation W20163416091 @default.
- W2016341609 hasLocation W20163416092 @default.
- W2016341609 hasOpenAccess W2016341609 @default.
- W2016341609 hasPrimaryLocation W20163416091 @default.
- W2016341609 hasRelatedWork W1968072793 @default.
- W2016341609 hasRelatedWork W1968877894 @default.
- W2016341609 hasRelatedWork W1983415836 @default.
- W2016341609 hasRelatedWork W2009362775 @default.
- W2016341609 hasRelatedWork W2015175351 @default.
- W2016341609 hasRelatedWork W2037370208 @default.
- W2016341609 hasRelatedWork W2038023588 @default.
- W2016341609 hasRelatedWork W2075719179 @default.
- W2016341609 hasRelatedWork W4387492829 @default.
- W2016341609 hasRelatedWork W623927881 @default.
- W2016341609 hasVolume "55" @default.
- W2016341609 isParatext "false" @default.
- W2016341609 isRetracted "false" @default.
- W2016341609 magId "2016341609" @default.
- W2016341609 workType "article" @default.