Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016345521> ?p ?o ?g. }
- W2016345521 endingPage "487" @default.
- W2016345521 startingPage "475" @default.
- W2016345521 abstract "Replication of alphaviruses strongly depends on the promoters located in the plus- and minus-strands of virus-specific RNAs. The most sophisticated promoter is encoded by the 5' end of the viral genome. This RNA sequence is involved in the initiation of translation of viral nsPs, and synthesis of both minus- and plus-strands of the viral genome. Part of the promoter, the 51-nt conserved sequence element (CSE), is located in the nsP1-coding sequence, and this limits the spectrum of possible mutations that can be performed. We designed a recombinant Venezuelan equine encephalitis virus genome, in which the promoter and nsP1-coding sequences are separated. This modification has allowed us to perform a wide variety of genetic manipulations, without affecting the amino acid sequence of the nsPs, and to further investigate 51-nt CSE functioning. The results of this study suggest a direct interaction of the amino terminal domain of nsP2 with the 5' end of the viral genome." @default.
- W2016345521 created "2016-06-24" @default.
- W2016345521 creator A5001014405 @default.
- W2016345521 creator A5009102999 @default.
- W2016345521 creator A5011712629 @default.
- W2016345521 creator A5045768148 @default.
- W2016345521 date "2007-06-01" @default.
- W2016345521 modified "2023-09-25" @default.
- W2016345521 title "Adaptation of Venezuelan equine encephalitis virus lacking 51-nt conserved sequence element to replication in mammalian and mosquito cells" @default.
- W2016345521 cites W1509422165 @default.
- W2016345521 cites W1545301587 @default.
- W2016345521 cites W1556286201 @default.
- W2016345521 cites W1568604491 @default.
- W2016345521 cites W1591665016 @default.
- W2016345521 cites W1657414671 @default.
- W2016345521 cites W1667933161 @default.
- W2016345521 cites W1678182324 @default.
- W2016345521 cites W1735561674 @default.
- W2016345521 cites W1806643152 @default.
- W2016345521 cites W1855484651 @default.
- W2016345521 cites W1866111900 @default.
- W2016345521 cites W1921832335 @default.
- W2016345521 cites W1966175079 @default.
- W2016345521 cites W1968072008 @default.
- W2016345521 cites W1976443173 @default.
- W2016345521 cites W1982260888 @default.
- W2016345521 cites W1988176421 @default.
- W2016345521 cites W1992524960 @default.
- W2016345521 cites W1995403172 @default.
- W2016345521 cites W2017135128 @default.
- W2016345521 cites W2025290907 @default.
- W2016345521 cites W2049227607 @default.
- W2016345521 cites W2049449836 @default.
- W2016345521 cites W2050723214 @default.
- W2016345521 cites W2090117197 @default.
- W2016345521 cites W2093176488 @default.
- W2016345521 cites W2097935692 @default.
- W2016345521 cites W2101241031 @default.
- W2016345521 cites W2101411165 @default.
- W2016345521 cites W2116621112 @default.
- W2016345521 cites W2119889845 @default.
- W2016345521 cites W2122278014 @default.
- W2016345521 cites W2123792518 @default.
- W2016345521 cites W2123866020 @default.
- W2016345521 cites W2125434600 @default.
- W2016345521 cites W2129622364 @default.
- W2016345521 cites W2133712091 @default.
- W2016345521 cites W2134708393 @default.
- W2016345521 cites W2136373859 @default.
- W2016345521 cites W2147213759 @default.
- W2016345521 cites W2148748595 @default.
- W2016345521 cites W2162541544 @default.
- W2016345521 cites W2167367231 @default.
- W2016345521 cites W42303853 @default.
- W2016345521 cites W4232596502 @default.
- W2016345521 cites W4320800934 @default.
- W2016345521 doi "https://doi.org/10.1016/j.virol.2007.01.009" @default.
- W2016345521 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2810489" @default.
- W2016345521 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17292936" @default.
- W2016345521 hasPublicationYear "2007" @default.
- W2016345521 type Work @default.
- W2016345521 sameAs 2016345521 @default.
- W2016345521 citedByCount "30" @default.
- W2016345521 countsByYear W20163455212012 @default.
- W2016345521 countsByYear W20163455212013 @default.
- W2016345521 countsByYear W20163455212014 @default.
- W2016345521 countsByYear W20163455212015 @default.
- W2016345521 countsByYear W20163455212016 @default.
- W2016345521 countsByYear W20163455212018 @default.
- W2016345521 countsByYear W20163455212019 @default.
- W2016345521 countsByYear W20163455212020 @default.
- W2016345521 countsByYear W20163455212021 @default.
- W2016345521 crossrefType "journal-article" @default.
- W2016345521 hasAuthorship W2016345521A5001014405 @default.
- W2016345521 hasAuthorship W2016345521A5009102999 @default.
- W2016345521 hasAuthorship W2016345521A5011712629 @default.
- W2016345521 hasAuthorship W2016345521A5045768148 @default.
- W2016345521 hasBestOaLocation W20163455212 @default.
- W2016345521 hasConcept C101762097 @default.
- W2016345521 hasConcept C104317684 @default.
- W2016345521 hasConcept C140704245 @default.
- W2016345521 hasConcept C141231307 @default.
- W2016345521 hasConcept C150194340 @default.
- W2016345521 hasConcept C159047783 @default.
- W2016345521 hasConcept C2522874641 @default.
- W2016345521 hasConcept C2777062976 @default.
- W2016345521 hasConcept C2777474056 @default.
- W2016345521 hasConcept C54355233 @default.
- W2016345521 hasConcept C67705224 @default.
- W2016345521 hasConcept C86803240 @default.
- W2016345521 hasConcept C91779695 @default.
- W2016345521 hasConceptScore W2016345521C101762097 @default.
- W2016345521 hasConceptScore W2016345521C104317684 @default.
- W2016345521 hasConceptScore W2016345521C140704245 @default.
- W2016345521 hasConceptScore W2016345521C141231307 @default.
- W2016345521 hasConceptScore W2016345521C150194340 @default.
- W2016345521 hasConceptScore W2016345521C159047783 @default.
- W2016345521 hasConceptScore W2016345521C2522874641 @default.