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• W2016346583 abstract "Continuous and batch production of citric acid from sucrose has been investigated using Aspergillus niger NCIM 588. Mycelia of A. niger grown on cellulose microfibril forms a uniform and thin mycelial proliferation under controlled conditions of cultivation rich in oxygen. In the fed batch mode using a recycle reactor, the DO of the system was maintained at 20 mg l−1 using oxygen enriched air. This improved volumetric productivity to 1.85 g l−1 h−1 of citric acid, representing an increase of at least 15-fold over results obtained simultaneously using shake-flasks and 1.6-fold over a conventional aerated batch reactor. It was possible to substitute sucrose with sugarcane juice as a carbon source in a fed batch recycle system. An overall specific production rate of citric acid of 0.147 and 0.208 g g−1 h−1 was achieved using cane juice and sucrose, respectively. In continuous fermentation, a medium containing 50 g l−1 of sucrose was allowed to drip through the fabric support at a residence time of 20 h. As a result of interface interaction, a citric acid volumetric productivity of 2.08 g l−1 h−1 was achieved for 26 days without any significant loss of productivity." @default.
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• W2016346583 date "2001-05-01" @default.
• W2016346583 modified "2023-10-17" @default.
• W2016346583 title "Citric acid production by Aspergillus niger immobilized on cellulose microfibrils: influence of morphology and fermenter conditions on productivity" @default.
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• W2016346583 doi "https://doi.org/10.1016/s0032-9592(01)00155-8" @default.
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