FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016349668> ?p ?o ?g. }

• W2016349668 endingPage "521" @default.
• W2016349668 startingPage "511" @default.
• W2016349668 abstract "Not all ribosomes that initiate translation of an mRNA sequence will successfully complete it and produce a full-length protein product. By comparing the amounts of lacZ monomer and lacZ dimer protein expressed from a plasmid in a strictly controlled assay, we calculate a dimer to monomer ratio of 0.76. We interpret this to mean that ribosomes have a 76% chance of completing the synthesis of a beta-galactosidase polypeptide. The remaining 24% of the initiated chains end in processivity accidents. For the wild-type, premature RNA polymerase termination is found to account for roughly one-third of the processivity accidents. For the hyperaccurate SmP mutant, we observe a processivity of 0.28, but the presence of streptomycin improves this to 0.50. Thus, the hyperaccuracy with respect to missense substitutions for this mutant is accompanied by a reduced processivity. Addition of streptomycin increase the first error class and reduces the second one. This finding is relevant to the optimization of ribosome function and the growth performance of ribosome mutants." @default.
• W2016349668 created "2016-06-24" @default.
• W2016349668 creator A5035498945 @default.
• W2016349668 creator A5038143945 @default.
• W2016349668 date "1990-10-01" @default.
• W2016349668 modified "2023-09-30" @default.
• W2016349668 title "Processivity errors of gene expression in Escherichia coli" @default.
• W2016349668 cites W106097148 @default.
• W2016349668 cites W109408096 @default.
• W2016349668 cites W1491259047 @default.
• W2016349668 cites W1508621189 @default.
• W2016349668 cites W1513594078 @default.
• W2016349668 cites W1596524104 @default.
• W2016349668 cites W1619272169 @default.
• W2016349668 cites W1914679563 @default.
• W2016349668 cites W1977393741 @default.
• W2016349668 cites W1981447303 @default.
• W2016349668 cites W1985179016 @default.
• W2016349668 cites W1987749012 @default.
• W2016349668 cites W200012524 @default.
• W2016349668 cites W2001990082 @default.
• W2016349668 cites W2008365039 @default.
• W2016349668 cites W2023459169 @default.
• W2016349668 cites W2029132648 @default.
• W2016349668 cites W2040484644 @default.
• W2016349668 cites W2065762927 @default.
• W2016349668 cites W2070452601 @default.
• W2016349668 cites W2077685286 @default.
• W2016349668 cites W2097754218 @default.
• W2016349668 cites W2111052458 @default.
• W2016349668 cites W2124421482 @default.
• W2016349668 cites W2144047802 @default.
• W2016349668 cites W2145358657 @default.
• W2016349668 cites W2146756673 @default.
• W2016349668 cites W2173684331 @default.
• W2016349668 cites W2337605037 @default.
• W2016349668 cites W4247333655 @default.
• W2016349668 cites W52268483 @default.
• W2016349668 doi "https://doi.org/10.1016/s0022-2836(05)80164-0" @default.
• W2016349668 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2121997" @default.
• W2016349668 hasPublicationYear "1990" @default.
• W2016349668 type Work @default.
• W2016349668 sameAs 2016349668 @default.
• W2016349668 citedByCount "131" @default.
• W2016349668 countsByYear W20163496682012 @default.
• W2016349668 countsByYear W20163496682013 @default.
• W2016349668 countsByYear W20163496682014 @default.
• W2016349668 countsByYear W20163496682015 @default.
• W2016349668 countsByYear W20163496682016 @default.
• W2016349668 countsByYear W20163496682017 @default.
• W2016349668 countsByYear W20163496682018 @default.
• W2016349668 countsByYear W20163496682019 @default.
• W2016349668 countsByYear W20163496682020 @default.
• W2016349668 countsByYear W20163496682021 @default.
• W2016349668 countsByYear W20163496682022 @default.
• W2016349668 countsByYear W20163496682023 @default.
• W2016349668 crossrefType "journal-article" @default.
• W2016349668 hasAuthorship W2016349668A5035498945 @default.
• W2016349668 hasAuthorship W2016349668A5038143945 @default.
• W2016349668 hasConcept C104317684 @default.
• W2016349668 hasConcept C105580179 @default.
• W2016349668 hasConcept C131140672 @default.
• W2016349668 hasConcept C143065580 @default.
• W2016349668 hasConcept C149364088 @default.
• W2016349668 hasConcept C153911025 @default.
• W2016349668 hasConcept C170344550 @default.
• W2016349668 hasConcept C185592680 @default.
• W2016349668 hasConcept C3675279 @default.
• W2016349668 hasConcept C54355233 @default.
• W2016349668 hasConcept C547475151 @default.
• W2016349668 hasConcept C67705224 @default.
• W2016349668 hasConcept C82381507 @default.
• W2016349668 hasConcept C86803240 @default.
• W2016349668 hasConcept C88478588 @default.
• W2016349668 hasConceptScore W2016349668C104317684 @default.
• W2016349668 hasConceptScore W2016349668C105580179 @default.
• W2016349668 hasConceptScore W2016349668C131140672 @default.
• W2016349668 hasConceptScore W2016349668C143065580 @default.
• W2016349668 hasConceptScore W2016349668C149364088 @default.
• W2016349668 hasConceptScore W2016349668C153911025 @default.
• W2016349668 hasConceptScore W2016349668C170344550 @default.
• W2016349668 hasConceptScore W2016349668C185592680 @default.
• W2016349668 hasConceptScore W2016349668C3675279 @default.
• W2016349668 hasConceptScore W2016349668C54355233 @default.
• W2016349668 hasConceptScore W2016349668C547475151 @default.
• W2016349668 hasConceptScore W2016349668C67705224 @default.
• W2016349668 hasConceptScore W2016349668C82381507 @default.
• W2016349668 hasConceptScore W2016349668C86803240 @default.
• W2016349668 hasConceptScore W2016349668C88478588 @default.
• W2016349668 hasIssue "4" @default.
• W2016349668 hasLocation W20163496681 @default.
• W2016349668 hasLocation W20163496682 @default.
• W2016349668 hasOpenAccess W2016349668 @default.
• W2016349668 hasPrimaryLocation W20163496681 @default.
• W2016349668 hasRelatedWork W1872846815 @default.
• W2016349668 hasRelatedWork W1963961621 @default.
• W2016349668 hasRelatedWork W1974750432 @default.
• W2016349668 hasRelatedWork W2030400410 @default.

• next