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• W2016350557 startingPage "43" @default.
• W2016350557 abstract "The development of comprehensive strategies for biomarker discovery of gynecological cancers is needed. The unique physiology of the female genital track revolves around ovulatory cycles ending by the proteolysis of the endometrium triggered by progesterone decline during the last part of the luteal phase. Building on the known link between incessant ovulation and ovarian cancer, we hypothesize that life-long menstruations could damage neighboring organs such as fallopian tubes, ovaries and peritoneum via endometrial secretions, and thus endometrium neighboring structures may have developed highly efficient protective strategies that could, in turn, be hijacked by cancer cells for survival and invasion. After literature review, we could classify the molecules involved in ovulation and menstruation pathways in three main categories: proteases, proteases inhibitors and cell-surface protectors. Strikingly, all validated biomarkers for ovarian cancers belong to at least one of these categories. We thus propose the development of comprehensive methods for identification of early diagnostic markers for gynecological cancers using systematical mapping and characterization of surface or soluble molecules belonging to physiological pathways linked to menstruation and differently expressed during luteal cycles." @default.
• W2016350557 created "2016-06-24" @default.
• W2016350557 creator A5020001580 @default.
• W2016350557 creator A5039245628 @default.
• W2016350557 date "2010-01-29" @default.
• W2016350557 modified "2023-09-27" @default.
• W2016350557 title "From the endometrium physiology to a comprehensive strategy for the discovery of ovarian cancer biomarkers" @default.
• W2016350557 cites W138135214 @default.
• W2016350557 cites W1491678226 @default.
• W2016350557 cites W1591513747 @default.
• W2016350557 cites W1592007606 @default.
• W2016350557 cites W1594529839 @default.
• W2016350557 cites W1594695427 @default.
• W2016350557 cites W1596171810 @default.
• W2016350557 cites W1915721030 @default.
• W2016350557 cites W1961928411 @default.
• W2016350557 cites W1965657663 @default.
• W2016350557 cites W1968091639 @default.
• W2016350557 cites W1968372807 @default.
• W2016350557 cites W1968444539 @default.
• W2016350557 cites W1970637166 @default.
• W2016350557 cites W1972973612 @default.
• W2016350557 cites W1974089832 @default.
• W2016350557 cites W1975593847 @default.
• W2016350557 cites W1975706974 @default.
• W2016350557 cites W1977298105 @default.
• W2016350557 cites W1977685162 @default.
• W2016350557 cites W1977789541 @default.
• W2016350557 cites W1979568379 @default.
• W2016350557 cites W1982643629 @default.
• W2016350557 cites W1985613060 @default.
• W2016350557 cites W1985705607 @default.
• W2016350557 cites W1991356027 @default.
• W2016350557 cites W1991521290 @default.
• W2016350557 cites W1992084421 @default.
• W2016350557 cites W1995910380 @default.
• W2016350557 cites W1996066317 @default.
• W2016350557 cites W1997223786 @default.
• W2016350557 cites W1997830584 @default.
• W2016350557 cites W1998029054 @default.
• W2016350557 cites W1998064365 @default.
• W2016350557 cites W2002661498 @default.
• W2016350557 cites W2003541535 @default.
• W2016350557 cites W2003755726 @default.
• W2016350557 cites W2006052075 @default.
• W2016350557 cites W2007161969 @default.
• W2016350557 cites W2007269627 @default.
• W2016350557 cites W2007671824 @default.
• W2016350557 cites W2008502642 @default.
• W2016350557 cites W2010011314 @default.
• W2016350557 cites W2011597615 @default.
• W2016350557 cites W2014496353 @default.
• W2016350557 cites W2015805460 @default.
• W2016350557 cites W2017239599 @default.
• W2016350557 cites W2017339970 @default.
• W2016350557 cites W2023414851 @default.
• W2016350557 cites W2024249553 @default.
• W2016350557 cites W2028659031 @default.
• W2016350557 cites W2030214755 @default.
• W2016350557 cites W2031243108 @default.
• W2016350557 cites W2031975339 @default.
• W2016350557 cites W2032038471 @default.
• W2016350557 cites W2032378930 @default.
• W2016350557 cites W2033501360 @default.
• W2016350557 cites W2033887922 @default.
• W2016350557 cites W2034301742 @default.
• W2016350557 cites W2035038195 @default.
• W2016350557 cites W2035548685 @default.
• W2016350557 cites W2045382498 @default.
• W2016350557 cites W2046148841 @default.
• W2016350557 cites W2047203711 @default.
• W2016350557 cites W2048291886 @default.
• W2016350557 cites W2050396069 @default.
• W2016350557 cites W2052328580 @default.
• W2016350557 cites W2052480751 @default.
• W2016350557 cites W2052716289 @default.
• W2016350557 cites W2054022111 @default.
• W2016350557 cites W2054571853 @default.
• W2016350557 cites W2054572564 @default.
• W2016350557 cites W2059671018 @default.
• W2016350557 cites W2061070956 @default.
• W2016350557 cites W2063641184 @default.
• W2016350557 cites W2065117328 @default.
• W2016350557 cites W2070366694 @default.
• W2016350557 cites W2071540706 @default.
• W2016350557 cites W2071619134 @default.
• W2016350557 cites W2073869703 @default.
• W2016350557 cites W2073883983 @default.
• W2016350557 cites W2085585495 @default.
• W2016350557 cites W2088631802 @default.
• W2016350557 cites W2089723143 @default.
• W2016350557 cites W2090197643 @default.
• W2016350557 cites W2094780144 @default.
• W2016350557 cites W2098419540 @default.
• W2016350557 cites W2100588878 @default.
• W2016350557 cites W2102719470 @default.
• W2016350557 cites W2102732690 @default.
• W2016350557 cites W2106049918 @default.

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