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- W2016351011 abstract "Abstract The purpose of this work was to determine if ovine lymphocyte antigen (OLA) type was associated with level of resistance and whether it could be used as a predictive test for identifying responsiveness of animals to vaccination against the parasite T. colubriformis . Antisera to ovine class I lymphocyte antigens were used to measure the frequency of three OLA types in merino sheep bred as either high or low responders to vaccination and challenge with T. colubriformis . A particular combination of lymphocyte antigens (SY la + lb) appeared to be associated with low faecal egg counts (resistant), and high faecal egg counts (susceptible) appeared to be associated with other OLA types, such as SY2. When high and low responder data were pooled, 56 ewes with SY la + lb, had a mean count of 149 eggs per gram (e.p.g) of faeces and 69 ewes with SY2 had 560 e.p.g. For 28 rams with SY la + lb, the mean count was 317 e.p.g. and 51 rams with SY2 had 1143 e.p.g. Overall these results were statistically highly significant. Separate analysis of each line showed that high responders, with SY la + lb had a mean count slightly below those with all other combinations within the same line, but this was not statistically significant. The SY la + lb type was not present in low responder males but in 11 low responder females this type was associated with significantly increased egg count. It was concluded that the case has yet to be proven that SY la + lb is a predictive marker for parasite resistance and not merely a foundation effect resulting from the selection and mating of particular sires." @default.
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- W2016351011 date "1986-08-01" @default.
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- W2016351011 title "The relationship between ovine lymphocyte antigens and faecal egg count of sheep selected for responsiveness to vaccination against Trichostrongylus colubriformis" @default.
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- W2016351011 doi "https://doi.org/10.1016/0020-7519(86)90116-5" @default.
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