Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016351102> ?p ?o ?g. }
- W2016351102 endingPage "101" @default.
- W2016351102 startingPage "93" @default.
- W2016351102 abstract "To evaluate individual cancer susceptibility, 170 previously untreated patients with pathologically-confirmed squamous cell carcinoma of the oral cavity, pharynx, and larynx, and 175 age- and sex-matched health controls were investigated for the occurrence of cancer in first-degree relatives along with other established risk factors for head and neck cancer. More than 54% of these subjects were assayed for mutagen sensitivity by quantifying in-vitro bleomycin-induced chromosomal breaks within peripheral blood lymphocytes. After adjusting for age, gender, education, family income, tobacco and alcohol consumption, the odds ratio associated with three or more first-degree relatives with cancer at any site was 3.79 (95% CI 0.9-15.9) with a linearly-increased trend in risk (P = 0.040). Significantly elevated risk was found to be associated with a history of cancer within siblings (OR = 2.61, 1.2-5.6, P = 0.014). Patients with a family cancer history and mutagen sensitivity were at greatest risk (OR = 7.88, 2.5-25.3, P = 0.005), indicating an additive interactive effect. The findings suggested that genetic familial influence is important in the causation of head and neck cancer." @default.
- W2016351102 created "2016-06-24" @default.
- W2016351102 creator A5004535291 @default.
- W2016351102 creator A5012002845 @default.
- W2016351102 creator A5015892149 @default.
- W2016351102 creator A5030302656 @default.
- W2016351102 creator A5077139468 @default.
- W2016351102 date "1999-11-01" @default.
- W2016351102 modified "2023-09-23" @default.
- W2016351102 title "Family history of cancer, mutagen sensitivity, and increased risk of head and neck cancer" @default.
- W2016351102 cites W1602091008 @default.
- W2016351102 cites W1969594381 @default.
- W2016351102 cites W1976383200 @default.
- W2016351102 cites W1977100264 @default.
- W2016351102 cites W1978368810 @default.
- W2016351102 cites W1996763899 @default.
- W2016351102 cites W1997239599 @default.
- W2016351102 cites W1998797601 @default.
- W2016351102 cites W2005421632 @default.
- W2016351102 cites W2015272991 @default.
- W2016351102 cites W2021072789 @default.
- W2016351102 cites W2038320777 @default.
- W2016351102 cites W2039256303 @default.
- W2016351102 cites W2039344439 @default.
- W2016351102 cites W2041719241 @default.
- W2016351102 cites W2062119404 @default.
- W2016351102 cites W2083892167 @default.
- W2016351102 cites W2087225074 @default.
- W2016351102 cites W2088496504 @default.
- W2016351102 cites W2094605499 @default.
- W2016351102 cites W2098744616 @default.
- W2016351102 cites W2112541923 @default.
- W2016351102 cites W2113104785 @default.
- W2016351102 cites W2113316373 @default.
- W2016351102 cites W2113482260 @default.
- W2016351102 cites W2127424871 @default.
- W2016351102 cites W2140320332 @default.
- W2016351102 cites W2148747607 @default.
- W2016351102 cites W2153689911 @default.
- W2016351102 cites W2162304185 @default.
- W2016351102 cites W2170909879 @default.
- W2016351102 cites W2170958906 @default.
- W2016351102 cites W2171637876 @default.
- W2016351102 cites W2312908991 @default.
- W2016351102 cites W4252927749 @default.
- W2016351102 cites W4254304914 @default.
- W2016351102 doi "https://doi.org/10.1016/s0304-3835(99)00249-9" @default.
- W2016351102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10656614" @default.
- W2016351102 hasPublicationYear "1999" @default.
- W2016351102 type Work @default.
- W2016351102 sameAs 2016351102 @default.
- W2016351102 citedByCount "37" @default.
- W2016351102 countsByYear W20163511022013 @default.
- W2016351102 countsByYear W20163511022014 @default.
- W2016351102 countsByYear W20163511022015 @default.
- W2016351102 countsByYear W20163511022016 @default.
- W2016351102 countsByYear W20163511022019 @default.
- W2016351102 countsByYear W20163511022020 @default.
- W2016351102 countsByYear W20163511022022 @default.
- W2016351102 crossrefType "journal-article" @default.
- W2016351102 hasAuthorship W2016351102A5004535291 @default.
- W2016351102 hasAuthorship W2016351102A5012002845 @default.
- W2016351102 hasAuthorship W2016351102A5015892149 @default.
- W2016351102 hasAuthorship W2016351102A5030302656 @default.
- W2016351102 hasAuthorship W2016351102A5077139468 @default.
- W2016351102 hasConcept C114246631 @default.
- W2016351102 hasConcept C121608353 @default.
- W2016351102 hasConcept C126322002 @default.
- W2016351102 hasConcept C141071460 @default.
- W2016351102 hasConcept C143998085 @default.
- W2016351102 hasConcept C156957248 @default.
- W2016351102 hasConcept C2776232574 @default.
- W2016351102 hasConcept C2776530083 @default.
- W2016351102 hasConcept C2776639595 @default.
- W2016351102 hasConcept C2776694085 @default.
- W2016351102 hasConcept C2780474809 @default.
- W2016351102 hasConcept C2781179581 @default.
- W2016351102 hasConcept C54355233 @default.
- W2016351102 hasConcept C71924100 @default.
- W2016351102 hasConcept C86803240 @default.
- W2016351102 hasConceptScore W2016351102C114246631 @default.
- W2016351102 hasConceptScore W2016351102C121608353 @default.
- W2016351102 hasConceptScore W2016351102C126322002 @default.
- W2016351102 hasConceptScore W2016351102C141071460 @default.
- W2016351102 hasConceptScore W2016351102C143998085 @default.
- W2016351102 hasConceptScore W2016351102C156957248 @default.
- W2016351102 hasConceptScore W2016351102C2776232574 @default.
- W2016351102 hasConceptScore W2016351102C2776530083 @default.
- W2016351102 hasConceptScore W2016351102C2776639595 @default.
- W2016351102 hasConceptScore W2016351102C2776694085 @default.
- W2016351102 hasConceptScore W2016351102C2780474809 @default.
- W2016351102 hasConceptScore W2016351102C2781179581 @default.
- W2016351102 hasConceptScore W2016351102C54355233 @default.
- W2016351102 hasConceptScore W2016351102C71924100 @default.
- W2016351102 hasConceptScore W2016351102C86803240 @default.
- W2016351102 hasIssue "1" @default.
- W2016351102 hasLocation W20163511021 @default.
- W2016351102 hasLocation W20163511022 @default.